High Interocular Corneal Symmetry in Average Simulated Keratometry, Central Corneal Thickness, and Posterior Elevation

Purpose. The purpose of this study was to assess interocular corneal symmetry in average simulated keratometry, corneal thickness, and posterior corneal elevation. Methods. This retrospective analysis included data from scanning slit topography (Orbscan II; Bausch and Lomb, Rochester, NY) on 242 eyes from 121 consecutive patients undergoing standard evaluation for consideration of elective laser vision correction. The symmetry between the right and left eye in average simulated keratometry, minimum central corneal thickness, and posterior corneal elevation was assessed by comparative data analysis. Results. Simulated keratometry ranged from 39.9 to 48.6 D. The interocular difference in average simulated keratometry was 0.47 D (standard deviation [SD] 0.43). The interocular Pearson correlation coefficient for average simulated keratometry was 0.90 (p < 0.001). The range of minimum corneal thickness was 432 to 628 &mgr;m. The interocular Pearson correlation coefficient for minimum central corneal thickness was 0.95 (p < 0.001). Right and left eye minimum corneal thickness differed by an average 8 &mgr;m (SD 7). The range of posterior elevation was -4 to 54 &mgr;m. The average difference in posterior corneal elevation between the right and left eye was 6 &mgr;m (SD 5). The interocular Pearson correlation coefficient for posterior corneal elevation was 0.72 (p < 0.001). The average posterior elevation was 19 &mgr;m (SD 11). Conclusions. Although a wide range of values exists in simulated keratometry, minimum corneal thickness, and posterior corneal elevation, interocular symmetry in all these parameters was very high in this group of consecutive patients. Asymmetry of these interocular parameters may warrant repeat clinical testing for accuracy and may predict corneal abnormalities. Normative data on posterior cornea elevation is presented. This study points out potentially clinically important high interocular corneal symmetry data in simulated keratometry, corneal thickness, and posterior corneal elevation.

[1]  Y. Rabinowitz Videokeratographic indices to aid in screening for keratoconus. , 1995, Journal of refractive surgery.

[2]  G. Auffarth,et al.  Keratoconus evaluation using the Orbscan Topography System. , 2000, Journal of cataract and refractive surgery.

[3]  Gerd U. Auffarth,et al.  Measuring anterior chamber depth with the Orbscan Topography System , 1997, Journal of cataract and refractive surgery.

[4]  C. Joo,et al.  Corneal ectasia detected after laser in situ keratomileusis for correction of less than -12 diopters of myopia. , 2000, Journal of cataract and refractive surgery.

[5]  H W Thompson,et al.  Corneal thickness measurements with the Orbscan Topography System and ultrasonic pachymetry , 1997, Journal of cataract and refractive surgery.

[6]  H. Oxlund,et al.  Biomechanical properties of keratoconus and normal corneas. , 1980, Experimental eye research.

[7]  M. Doughty,et al.  Human corneal thickness and its impact on intraocular pressure measures: a review and meta-analysis approach. , 2000, Survey of ophthalmology.

[8]  D. Altman,et al.  Measuring agreement in method comparison studies , 1999, Statistical methods in medical research.

[9]  C. Roberts The cornea is not a piece of plastic. , 2000, Journal of refractive surgery.

[10]  T. Seiler,et al.  Iatrogenic keratectasia after laser in situ keratomileusis. , 1998, Journal of refractive surgery.