Institute of Physics Publishing Journal of Micromechanics and Microengineering Wet Anisotropic Etching for Fluidic 1d Nanochannels

In this paper a method is proposed to fabricate channels for fluidic applications with a depth in the nanometer range. Channels with smooth and straight sidewalls are constructed with the help of micromachining technology by etching shallow trenches into 110 silicon using native oxide as a mask material and OPD resist developer as the etchant. Sub-50 nm deep fluidic channels are formed after bonding the nanopatterned wafers with silicon or borofloat-glass wafers. The nanofabrication process is significantly simplified by using native oxide as the main mask material. The etch depth of the nanochannels is limited by the thickness of the native oxide layer, and by the selectivity of the oxide/silicon etch rate (estimated to be at least 250 for 110 silicon at room temperature).

[1]  A. van den Berg,et al.  Nanofluidic bubble pump using surface tension directed gas injection. , 2002, Analytical chemistry.

[2]  J. Korlach,et al.  DNA fragment sizing by single molecule detection in submicrometer-sized closed fluidic channels. , 2002, Analytical chemistry.

[3]  H. Craighead,et al.  Heat-depolymerizable polycarbonates as electron beam patternable sacrificial layers for nanofluidics , 2001 .

[4]  H. Craighead,et al.  Nanofabricated refractive index sensor based on photon tunneling in nanofluidic channel , 2001 .

[5]  Mona E. Zaghloul,et al.  Fabrication techniques to realize CMOS-compatible microfluidic microchannels , 2001 .

[6]  Peter Enoksson,et al.  Micromachined flow-through filter-chamber for chemical reactions on beads , 2000 .

[7]  M. Elwenspoek,et al.  Fabrication of micromachined pipettes in a flow channel for single molecule handling of DNA , 2000, Proceedings IEEE Thirteenth Annual International Conference on Micro Electro Mechanical Systems (Cat. No.00CH36308).

[8]  Man Wong,et al.  Phase change in microchannel heat sink under forced convection boiling , 2000, Proceedings IEEE Thirteenth Annual International Conference on Micro Electro Mechanical Systems (Cat. No.00CH36308).

[9]  Harold G. Craighead,et al.  Entropic trapping and sieving of long DNA molecules in a nanofluidic channel , 1999 .

[10]  K. R. Williams,et al.  Novel interconnection technologies for integrated microfluidic systems , 1998 .

[11]  Donald W. Sweeney,et al.  Generation of subquarter-micron resist structures using optical interference lithography and image reversal , 1997 .

[12]  Jane E. Curtin,et al.  Nanochannel fabrication for chemical sensors , 1997 .

[13]  Kenji Kurihara,et al.  Fabrication of sub‐10‐nm silicon lines with minimum fluctuation , 1995 .

[14]  X. Zhang Electrochemistry of silicon and its oxide , 2001 .