Ufbp1 promotes plasma cell development and ER expansion by modulating distinct branches of UPR

[1]  D. Allman,et al.  Protocol for improved resolution of plasma cell subpopulations by flow cytometry , 2017, European journal of immunology.

[2]  C. Berek,et al.  A new staining protocol for detection of murine antibody‐secreting plasma cell subsets by flow cytometry , 2017, European journal of immunology.

[3]  Howard Y. Chang,et al.  The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity , 2017, Cell.

[4]  R. Gibbs,et al.  Loss of DDRGK1 modulates SOX9 ubiquitination in spondyloepimetaphyseal dysplasia , 2017, The Journal of clinical investigation.

[5]  Jiahui Tao,et al.  The luminal domain of the ER stress sensor protein PERK binds misfolded proteins and thereby triggers PERK oligomerization , 2017, The Journal of Biological Chemistry.

[6]  Lizhi Song,et al.  A critical role of DDRGK1 in endoplasmic reticulum homoeostasis via regulation of IRE1α stability , 2017, Nature Communications.

[7]  Thomas Meitinger,et al.  Biallelic Variants in UBA5 Reveal that Disruption of the UFM1 Cascade Can Result in Early-Onset Encephalopathy. , 2016, American journal of human genetics.

[8]  M. Hurles,et al.  Biallelic Variants in UBA5 Link Dysfunctional UFM1 Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy. , 2016, American journal of human genetics.

[9]  Konstantinos Biliouris,et al.  Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8 , 2015, Nature Immunology.

[10]  W. Shi,et al.  Blimp-1 controls plasma cell function through regulation of immunoglobulin secretion and the unfolded protein response , 2015, Nature Immunology.

[11]  B. Pace,et al.  UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid Development , 2015, PLoS genetics.

[12]  Lorna M. Lopez,et al.  Genome-wide association studies identify genetic loci for low von Willebrand factor levels , 2015, European Journal of Human Genetics.

[13]  Laura A. Crinnion,et al.  Identification of a mutation in the ubiquitin-fold modifier 1-specific peptidase 2 gene, UFSP2, in an extended South African family with Beukes hip dysplasia. , 2015, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[14]  J. Weissman,et al.  Regulation of mRNA translation during mitosis , 2015, eLife.

[15]  B. Pace,et al.  RCAD/Ufl1, a Ufm1 E3 ligase, is essential for hematopoietic stem cell function and murine hematopoiesis , 2015, Cell Death and Differentiation.

[16]  Wei Shi,et al.  Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells , 2015, Nature Immunology.

[17]  Philip D. Hodgkin,et al.  The generation of antibody-secreting plasma cells , 2015, Nature Reviews Immunology.

[18]  Wei Shi,et al.  The transcription factors IRF8 and PU.1 negatively regulate plasma cell differentiation , 2014, The Journal of experimental medicine.

[19]  Chuong B. Do,et al.  Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson’s disease , 2014, Nature Genetics.

[20]  D. Toncheva,et al.  Whole genome methylation analyses of schizophrenia patients before and after treatment , 2014, Biotechnology, biotechnological equipment.

[21]  E. Laurenti,et al.  The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress , 2014, Nature.

[22]  Adam B. Olshen,et al.  The translational landscape of the mammalian cell cycle. , 2013, Molecular cell.

[23]  U. Klein,et al.  Article Transcriptional Regulation of Germinal Center B and Plasma Cell Fates by Dynamical Control of Irf4 , 2022 .

[24]  Mingsheng Zhang,et al.  Transcriptional Regulation of the Ufm1 Conjugation System in Response to Disturbance of the Endoplasmic Reticulum Homeostasis and Inhibition of Vesicle Trafficking , 2012, PloS one.

[25]  S. Nutt,et al.  High Rate of Antibody Secretion Is not Integral to Plasma Cell Differentiation as Revealed by XBP-1 Deficiency , 2012, The Journal of Immunology.

[26]  L. P. Vaites,et al.  PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation , 2012, Molecular and Cellular Biology.

[27]  Nicholas T. Ingolia,et al.  The translational landscape of mTOR signalling steers cancer initiation and metastasis , 2012, Nature.

[28]  Peter Walter,et al.  Unfolded Proteins Are Ire1-Activating Ligands That Directly Induce the Unfolded Protein Response , 2011, Science.

[29]  N. Enomoto,et al.  Genome-wide association study identified ITPA/DDRGK1 variants reflecting thrombocytopenia in pegylated interferon and ribavirin therapy for chronic hepatitis C. , 2011, Human molecular genetics.

[30]  Shifeng Xue,et al.  Ribosome-Mediated Specificity in Hox mRNA Translation and Vertebrate Tissue Patterning , 2011, Cell.

[31]  Kezhong Zhang,et al.  The unfolded protein response transducer IRE1α prevents ER stress‐induced hepatic steatosis , 2011, The EMBO journal.

[32]  M. Granvik,et al.  Ubiquitin Fold Modifier 1 (UFM1) and Its Target UFBP1 Protect Pancreatic Beta Cells from ER Stress-Induced Apoptosis , 2011, PloS one.

[33]  D. Ron,et al.  Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress , 2011, Nature Cell Biology.

[34]  Keiji Tanaka,et al.  The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice , 2011, Nature communications.

[35]  S. Benhamron,et al.  Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling , 2011, European journal of immunology.

[36]  K. Calame,et al.  Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch , 2010, The EMBO journal.

[37]  M. Sone,et al.  Suppression of the novel ER protein Maxer by mutant ataxin‐1 in Bergman glia contributes to non‐cell‐autonomous toxicity , 2010, The EMBO journal.

[38]  L. Hendershot,et al.  Plasma cell differentiation initiates a limited ER stress response by specifically suppressing the PERK-dependent branch of the unfolded protein response , 2010, Cell Stress and Chaperones.

[39]  M. Kasahara,et al.  A Novel Type of E3 Ligase for the Ufm1 Conjugation System* , 2009, The Journal of Biological Chemistry.

[40]  B. Volpe,et al.  XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development , 2009, The Journal of experimental medicine.

[41]  J. C. Love,et al.  XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells , 2009, The EMBO journal.

[42]  Barbara C. McGrath,et al.  PERK is essential for neonatal skeletal development to regulate osteoblast proliferation and differentiation , 2008, Journal of cellular physiology.

[43]  J. W. Brewer,et al.  The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells. , 2008, Molecular immunology.

[44]  Jhagvaral Hasbold,et al.  Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1. , 2007, Immunity.

[45]  Barbara C. McGrath,et al.  PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. , 2006, Cell metabolism.

[46]  Zhaohui Xu,et al.  The crystal structure of human IRE1 luminal domain reveals a conserved dimerization interface required for activation of the unfolded protein response , 2006, Proceedings of the National Academy of Sciences.

[47]  Roger Sciammas,et al.  Graded expression of interferon regulatory factor-4 coordinates isotype switching with plasma cell differentiation. , 2006, Immunity.

[48]  Qiong Shen,et al.  Transcription factor IRF4 controls plasma cell differentiation and class-switch recombination , 2006, Nature Immunology.

[49]  J. Buerstedde,et al.  Loss of Pax5 promotes plasma cell differentiation. , 2006, Immunity.

[50]  M. Busslinger,et al.  Gene repression by Pax5 in B cells is essential for blood cell homeostasis and is reversed in plasma cells. , 2006, Immunity.

[51]  Gerald C. Chu,et al.  XBP‐1 is required for biogenesis of cellular secretory machinery of exocrine glands , 2005, The EMBO journal.

[52]  Jianping Liu,et al.  Isolation and Characterization of Ubiquitin-activating Enzyme E1-domain Containing 1, UBE1DC1 , 2005, Molecular Biology Reports.

[53]  K. Mori,et al.  XBP1 , 2004, The Journal of Cell Biology.

[54]  L. Staudt,et al.  Direct Repression of prdm1 by Bcl-6 Inhibits Plasmacytic Differentiation1 , 2004, The Journal of Immunology.

[55]  S. Peng,et al.  Active Inhibition of Plasma Cell Development in Resting B Cells by Microphthalmia-associated Transcription Factor , 2004, The Journal of experimental medicine.

[56]  L. Staudt,et al.  XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. , 2004, Immunity.

[57]  Satoru Takahashi,et al.  The transcriptional programme of antibody class switching involves the repressor Bach2 , 2004, Nature.

[58]  Keiji Tanaka,et al.  A novel protein‐conjugating system for Ufm1, a ubiquitin‐fold modifier , 2004, The EMBO journal.

[59]  K. Calame,et al.  Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. , 2003, Immunity.

[60]  K. Toellner,et al.  Extrafollicular antibody responses , 2003, Immunological reviews.

[61]  Albert J R Heck,et al.  Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion. , 2003, Immunity.

[62]  Liming Yang,et al.  Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. , 2002, Immunity.

[63]  Peichuan Zhang,et al.  The PERK Eukaryotic Initiation Factor 2α Kinase Is Required for the Development of the Skeletal System, Postnatal Growth, and the Function and Viability of the Pancreas , 2002, Molecular and Cellular Biology.

[64]  K. Mori,et al.  XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription Factor , 2001, Cell.

[65]  Neal N. Iwakoshi,et al.  Plasma cell differentiation requires the transcription factor XBP-1 , 2001, Nature.

[66]  K. Calame,et al.  BLIMP-1 mediates extinction of major histocompatibility class II transactivator expression in plasma cells , 2000, Nature Immunology.

[67]  D. Calado,et al.  Germinal Centers , 2017, Methods in Molecular Biology.

[68]  M. Nussenzweig,et al.  Dopamine in germinal centers , 2017, Nature Immunology.