The use of trimethylsilyl cyanide derivatization for robust and broad-spectrum high-throughput gas chromatography–mass spectrometry based metabolomics

[1]  C. Poole.  Alkylsilyl derivatives for gas chromatography. , 2013, Journal of chromatography. A.

[2]  J. Amigo,et al.  Plant metabolomics: resolution and quantification of elusive peaks in liquid chromatography-mass spectrometry profiles of complex plant extracts using multi-way decomposition methods. , 2012, Journal of chromatography. A.

[3]  S. Huttunen,et al.  Comparison of the triterpenoid content of berries and leaves of lingonberry Vaccinium vitis-idaea from Finland and Poland. , 2012, Journal of agricultural and food chemistry.

[4]  S. Matsukawa,et al.  Polystyrene-supported TBD as an efficient and reusable organocatalyst for cyanosilylation of aldehydes, ketones, and imines , 2012 .

[5]  Dominique Van Der Straeten,et al.  Evaluation of automated sample preparation, retention time locked gas chromatography-mass spectrometry and data analysis methods for the metabolomic study of Arabidopsis species. , 2011, Journal of chromatography. A.

[6]  P. Spégel,et al.  Development of a gas chromatography/mass spectrometry based metabolomics protocol by means of statistical experimental design , 2011, Metabolomics.

[7]  J. Amigo,et al.  Comprehensive analysis of chromatographic data by using PARAFAC2 and principal components analysis. , 2010, Journal of chromatography. A.

[8]  Kishore K. Pasikanti,et al.  Gas chromatography/mass spectrometry in metabolic profiling of biological fluids. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[9]  M. Klapa,et al.  Standardizing GC-MS metabolomics. , 2008, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[10]  Oliver Fiehn,et al.  Extending the breadth of metabolite profiling by gas chromatography coupled to mass spectrometry. , 2008, Trends in analytical chemistry : TRAC.

[11]  A. Fernie,et al.  Gas chromatography mass spectrometry–based metabolite profiling in plants , 2006, Nature Protocols.

[12]  M. Naczk,et al.  Phenolic acid profiles in some small berries. , 2005, Journal of agricultural and food chemistry.

[13]  M. Sjöström,et al.  Design of experiments: an efficient strategy to identify factors influencing extraction and derivatization of Arabidopsis thaliana samples in metabolomic studies with gas chromatography/mass spectrometry. , 2004, Analytical biochemistry.

[14]  T. Nohara,et al.  Cytotoxic Triterpenes and Sterol from the Fruit of Rabbiteye Blueberry (Vaccinium ashei) , 2004 .

[15]  H. Prasad.  Organosilicon reagents in natural product synthesis , 2002 .

[16]  O. Fiehn,et al.  Identification of uncommon plant metabolites based on calculation of elemental compositions using gas chromatography and quadrupole mass spectrometry. , 2000, Analytical chemistry.

[17]  Ute Roessner,et al.  Simultaneous analysis of metabolites in potato tuber by gas chromatography-mass spectrometry. , 2000 .

[18]  James L. Little,et al.  Artifacts in trimethylsilyl derivatization reactions and ways to avoid them. , 1999, Journal of chromatography. A.

[19]  G. Patil,et al.  Alkylsilyl cyanides as silylating agents , 1986 .

[20]  Horst Schweer,et al.  Gas chromatography—mass spectrometry of aldoses as O-methoxime, O-2-methyl-2-propoxime and O-n-butoxime pèrtrifluoroacetyl derivatives on OV-225 with methylpropane as ionization agent , 1982 .

[21]  Pengxin Wang,et al.  Silylation of organic compounds , 1969 .

[22]  E. Horning,et al.  Formation and gas-liquid chromatographic behavior of isometric steroid ketone methoxime derivatives. , 1968, Analytical biochemistry.

[23]  G. A. Parker,et al.  Stereochemistry of Asymmetric Silicon. IV. The Sn2-Si Stereochemistry Rule for Good Leaving Groups , 1967 .

[24]  Rasmus Bro,et al.  Solving fundamental problems in chromatographic analysis , 2008, Analytical and bioanalytical chemistry.

[25]  V. Toome,et al.  The Use of Trimethylsilyl Cyanide in Gas Chromatographic Analysis , 1992 .

[26]  H. Lingeman,et al.  Derivatization reactions in the gas-liquid chromatographic analysis of drugs in biological fluids. , 1984, Journal of pharmaceutical and biomedical analysis.

[27]  J. Halket,et al.  Handbook of derivatives for chromatography , 1978 .

[28]  C. W. Gehreke,et al.  Gas-liquid chromatography of protein amino acid trimethylsilyl derivatives. , 1969, Journal of chromatography.

[29]  L. Birkofer.  Trennung von alkyl- und a-verzweigten alkylaminen ber n-silyl-derivate , 1968 .

[30]  H. Vandendool,et al.  A GENERALIZATION OF THE RETENTION INDEX SYSTEM INCLUDING LINEAR TEMPERATURE PROGRAMMED GAS-LIQUID PARTITION CHROMATOGRAPHY. , 1963, Journal of chromatography.

[31]  R. M. Pike.  Chemistry of the Silylamines. I. The Condensation of Monofunctional Silylamines with Monofunctional Silanols1 , 1961 .

[32]  H. Hotelling.  Analysis of a complex of statistical variables into principal components. , 1933 .