Altitude Training for Elite Endurance Performance: A 2012 Update

Abstract Altitude training is commonly used by endurance athletes and coaches in pursuit of enhancement of performance on return to sea level. The purpose of the current review article was to update and evaluate recent literature relevant to the practical application of altitude training for endurance athletes. Consequently, the literature can be considered in either of two categories: performance-led investigations or mechanistic advancements/insights. Each section discusses the relevant literature and proposes future directions where appropriate.

[1]  N. Berger,et al.  Influence of recombinant human erythropoietin treatment on pulmonary O2 uptake kinetics during exercise in humans , 2005, The Journal of physiology.

[2]  R. Withers,et al.  Longitudinal changes in haemoglobin mass and VO2max in adolescents , 2009, European Journal of Applied Physiology.

[3]  B. Ekblom,et al.  Blood volume and hemoglobin concentration as determinants of maximal aerobic power. , 1984, Medicine and science in sports and exercise.

[4]  J. Dempsey,et al.  Effects of incomplete pulmonary gas exchange on VO2 max. , 1989, Journal of applied physiology.

[5]  G. Ninot,et al.  Effects of recombinant human erythropoietin injections on physical self in endurance athletes , 2006, Journal of sports sciences.

[6]  W. Hopkins,et al.  Counterpoint: positive effects of intermittent hypoxia (live high:train low) on exercise performance are not mediated primarily by augmented red cell volume. , 2005, Journal of applied physiology.

[7]  J. Wehrlin,et al.  Does hemoglobin mass increase from age 16 to 21 and 28 in elite endurance athletes? , 2011, Medicine and science in sports and exercise.

[8]  B. Berglund,et al.  Effect of reinfusion of autologous blood on exercise performance in cross-country skiers. , 1987, International journal of sports medicine.

[9]  A. Pries,et al.  The Hematocrit Paradox – How Does Blood Doping Really Work? , 2010, International journal of sports medicine.

[10]  R. Wilber.  Introduction to altitude/hypoxic training symposium. , 2007, Medicine and science in sports and exercise.

[11]  Eileen Y. Robertson,et al.  Within-subject variation in hemoglobin mass in elite athletes. , 2012, Medicine and science in sports and exercise.

[12]  R. Jacobs,et al.  "Live high-train low" using normobaric hypoxia: a double-blinded, placebo-controlled study. , 2012, Journal of applied physiology.

[13]  Eileen Y. Robertson,et al.  Reproducibility of performance changes to simulated live high/train low altitude. , 2010, Medicine and science in sports and exercise.

[14]  C. Däpp,et al.  Experimental Physiology - Research Paper A hypoxia complement differentiates the muscle response to endurance exercise , 2012 .

[15]  B. Levine,et al.  Impairment of 3000-m run time at altitude is influenced by arterial oxyhemoglobin saturation. , 2011, Medicine and science in sports and exercise.

[16]  D. Pyne,et al.  Endurance training at altitude. , 2009, High altitude medicine & biology.

[17]  W. Schmidt,et al.  The optimised CO-rebreathing method: a new tool to determine total haemoglobin mass routinely , 2005, European Journal of Applied Physiology.

[18]  Will G Hopkins,et al.  Reliability of time to exhaustion analyzed with critical-power and log-log modeling. , 2005, Medicine and science in sports and exercise.

[19]  A. Sassi,et al.  Time course of the hemoglobin mass response to natural altitude training in elite endurance cyclists , 2012, Scandinavian journal of medicine & science in sports.

[20]  B. Friedmann-Bette,et al.  Total haemoglobin mass and red blood cell profile in endurance-trained and non-endurance-trained adolescent athletes , 2011, European Journal of Applied Physiology.

[21]  S. Powers,et al.  Linear relationship between VO2max and VO2max decrement during exposure to acute hypoxia. , 1988, Journal of applied physiology.

[22]  Nicolas Caesar Petersen,et al.  Effects of erythropoietin administration on cerebral metabolism and exercise capacity in men. , 2010, Journal of applied physiology.

[23]  David T. Martin,et al.  The contribution of haemoglobin mass to increases in cycling performance induced by simulated LHTL , 2011, European Journal of Applied Physiology.

[24]  R. Wilber,et al.  Application of altitude/hypoxic training by elite athletes. , 2007, Medicine and science in sports and exercise.

[25]  T. Simon,et al.  The effects of red blood cell infusion on 10-km race time. , 1987, JAMA.

[26]  N. Secher,et al.  Cerebral perturbations provoked by prolonged exercise , 2004, Progress in Neurobiology.

[27]  D. Pyne,et al.  Influence of altitude training modality on performance and total haemoglobin mass in elite swimmers , 2012, European Journal of Applied Physiology.

[28]  Eileen Y. Robertson,et al.  Effectiveness of intermittent training in hypoxia combined with live high/train low , 2010, European Journal of Applied Physiology.

[29]  B. Ekblom,et al.  Response to submaximal and maximal exercise at different levels of carboxyhemoglobin. , 1972, Acta physiologica Scandinavica.

[30]  M. Arcasoy.  The non‐haematopoietic biological effects of erythropoietin , 2008, British journal of haematology.

[31]  W. Schmidt,et al.  Impact of Alterations in Total Hemoglobin Mass on V˙O2max , 2010, Exercise and sport sciences reviews.

[32]  G. Semenza,et al.  Regulation of oxygen homeostasis by hypoxia-inducible factor 1. , 2009, Physiology.

[33]  C. Alfrey,et al.  The Negative Regulation of Red Cell Mass by Neocytolysis: Physiologic and Pathophysiologic Manifestations , 2005, Cellular Physiology and Biochemistry.

[34]  J P Richalet,et al.  Combining Hypoxic Methods for Peak Performance , 2010, Sports medicine.

[35]  M. Burtscher,et al.  Effects of Intermittent Hypoxia on Running Economy , 2010, International journal of sports medicine.

[36]  Eileen Y. Robertson,et al.  Effects of Simulated and Real Altitude Exposure in Elite Swimmers , 2010, Journal of strength and conditioning research.

[37]  David T. Martin,et al.  Seasonal variation of haemoglobin mass in internationally competitive female road cyclists , 2010, European Journal of Applied Physiology.

[38]  P. Saunders,et al.  Time course of haemoglobin mass during 21 days live high:train low simulated altitude , 2009, European Journal of Applied Physiology.

[39]  R. Thatcher,et al.  Influence of blood donation on O2 uptake on‐kinetics, peak O2 uptake and time to exhaustion during severe‐intensity cycle exercise in humans , 2006, Experimental physiology.

[40]  R. Wise,et al.  Erythropoietin Improves Mood and Modulates the Cognitive and Neural Processing of Emotion 3 Days Post Administration , 2008, Neuropsychopharmacology.

[41]  B. Ekblom.  Blood Doping and Erythropoietin: The Effects of Variation in Hemoglobin Concentration and Other Related Factors on Physical Performance , 1996, The American journal of sports medicine.

[42]  W G Hopkins,et al.  Variability of competitive performance of distance runners. , 2001, Medicine and science in sports and exercise.

[43]  B. Levine,et al.  Epo production at altitude in elite endurance athletes is not associated with the sea level hypoxic ventilatory response. , 2010, Journal of science and medicine in sport.

[44]  Will G Hopkins,et al.  Sea-Level Exercise Performance Following Adaptation to Hypoxia , 2009, Sports medicine.