Characterization of Inflammatory Bowel Disease With Urinary Metabolic Profiling

[1]  H. Ogata,et al.  Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease. , 2008, International journal of medical microbiology : IJMM.

[2]  Harry Sokol,et al.  Analysis of bacterial bowel communities of IBD patients: What has it revealed? , 2008, Inflammatory bowel diseases.

[3]  M. Elisaf,et al.  Gender‐related and age‐related urinalysis of healthy subjects by NMR‐based metabonomics , 2008, NMR in biomedicine.

[4]  Haifeng Lu,et al.  Symbiotic gut microbes modulate human metabolic phenotypes , 2008, Proceedings of the National Academy of Sciences.

[5]  R Balfour Sartor,et al.  Microbial influences in inflammatory bowel diseases. , 2008, Gastroenterology.

[6]  Martin Wiedmann,et al.  Culture independent analysis of ileal mucosa reveals a selective increase in invasive Escherichia coli of novel phylogeny relative to depletion of Clostridiales in Crohn's disease involving the ileum , 2007, The ISME Journal.

[7]  Russ Greiner,et al.  Investigations of the effects of gender, diurnal variation, and age in human urinary metabolomic profiles. , 2007, Analytical chemistry.

[8]  J. Doré,et al.  Patchy distribution of mucosal lesions in ileal Crohn's disease is not linked to differences in the dominant mucosa‐associated bacteria: A study using fluorescence in situ hybridization and temporal temperature gradient gel electrophoresis , 2007, Inflammatory bowel diseases.

[9]  R. Cox,et al.  A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human. , 2007, Physiological genomics.

[10]  Jeremiah Stamler,et al.  Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy. , 2007, Analytical chemistry.

[11]  I. Wilson,et al.  Rapid and noninvasive metabonomic characterization of inflammatory bowel disease. , 2007, Journal of proteome research.

[12]  Ying Zhang,et al.  HMDB: the Human Metabolome Database , 2007, Nucleic Acids Res..

[13]  J. Doré,et al.  Molecular comparison of dominant microbiota associated with injured versus healthy mucosa in ulcerative colitis , 2006, Gut.

[14]  A. Darzi,et al.  Diagnostic Precision of Anti-Saccharomyces cerevisiae Antibodies and Perinuclear Antineutrophil Cytoplasmic Antibodies in Inflammatory Bowel Disease , 2006, The American Journal of Gastroenterology.

[15]  Elaine Holmes,et al.  Susceptibility of human metabolic phenotypes to dietary modulation. , 2006, Journal of proteome research.

[16]  M. Walsh,et al.  Effect of acute dietary standardization on the urinary, plasma, and salivary metabolomic profiles of healthy humans. , 2006, The American journal of clinical nutrition.

[17]  J. V. van Duynhoven,et al.  Metabonomics approach to determine metabolic differences between green tea and black tea consumption. , 2006, Journal of agricultural and food chemistry.

[18]  R. Bibiloni,et al.  The bacteriology of biopsies differs between newly diagnosed, untreated, Crohn's disease and ulcerative colitis patients. , 2006, Journal of medical microbiology.

[19]  Elaine Holmes,et al.  Metabolic Profiling of CSF: Evidence That Early Intervention May Impact on Disease Progression and Outcome in Schizophrenia , 2006, PLoS medicine.

[20]  R. Sartor.  Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis , 2006, Nature Clinical Practice Gastroenterology &Hepatology.

[21]  J. Satsangi,et al.  Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. , 2005, Canadian journal of gastroenterology = Journal canadien de gastroenterologie.

[22]  Jimmy D Bell,et al.  Muscle metabolites, detected in urine by proton spectroscopy, correlate with disease damage in juvenile idiopathic inflammatory myopathies. , 2005, Arthritis and rheumatism.

[23]  Emmanuel Mikros,et al.  1H NMR-based metabonomics for the diagnosis of inborn errors of metabolism in urine , 2005 .

[24]  I. Wilson,et al.  Gut microorganisms, mammalian metabolism and personalized health care , 2005, Nature Reviews Microbiology.

[25]  J. Hampe,et al.  Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease , 2004, Gut.

[26]  E. Kuipers,et al.  The Metabolic Activity of Fecal Microbiota from Healthy Individuals and Patients with Inflammatory Bowel Disease , 2004, Digestive Diseases and Sciences.

[27]  Anthony F. P. Nash,et al.  A 1H NMR-based metabonomic study of urine and plasma samples obtained from healthy human subjects. , 2003, Journal of pharmaceutical and biomedical analysis.

[28]  Jeremy K Nicholson,et al.  NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats. , 2003, Chemical research in toxicology.

[29]  I. Wilson,et al.  Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism , 2003, Nature Reviews Drug Discovery.

[30]  J. Doré,et al.  Alterations of the dominant faecal bacterial groups in patients with Crohn's disease of the colon , 2003, Gut.

[31]  Jimmy D Bell,et al.  Urinary levels of creatine and other metabolites in the assessment of polymyositis and dermatomyositis. , 2003, Rheumatology.

[32]  J. Nicholson,et al.  Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics , 2002, Nature Medicine.

[33]  M. Reily,et al.  Effect of dexamethasone on the metabonomics profile associated with phosphodiesterase inhibitor-induced vascular lesions in rats. , 2002, Toxicology and applied pharmacology.

[34]  August Böck,et al.  The molecular biology of formate metabolism in enterobacteria. , 2002, Journal of molecular microbiology and biotechnology.

[35]  R. Williams,et al.  Effect of intestinal microflora on the urinary metabolic profile of rats: a 1 H-nuclear magnetic resonance spectroscopy study , 2002, Xenobiotica; the fate of foreign compounds in biological systems.

[36]  Elaine Holmes,et al.  Metabonomic applications in toxicity screening and disease diagnosis. , 2002, Current topics in medicinal chemistry.

[37]  E Holmes,et al.  Metabonomic investigations into hydrazine toxicity in the rat. , 2001, Chemical research in toxicology.

[38]  Age K. Smilde,et al.  Direct orthogonal signal correction , 2001 .

[39]  Ray L Somorjai,et al.  The use of 1H magnetic resonance spectroscopy in inflammatory bowel diseases: distinguishing ulcerative colitis from Crohn's disease , 2001, American Journal of Gastroenterology.

[40]  John C. Lindon,et al.  NMR Spectroscopy of Biofluids , 1999 .

[41]  R. Pounder,et al.  A simple clinical colitis activity index , 1998, Gut.

[42]  G. Macfarlane,et al.  Enumeration of human colonic bacteria producing phenolic and indolic compounds: effects of pH, carbohydrate availability and retention time on dissimilatory aromatic amino acid metabolism. , 1996, The Journal of applied bacteriology.

[43]  M Sandler,et al.  Gut flora and the origin of some urinary aromatic phenolic compounds. , 1994, Biochemical pharmacology.

[44]  P. Sadler,et al.  Urinary excretion of acetaminophen and its metabolites as studied by proton NMR spectroscopy. , 1984, Clinical chemistry.

[45]  R. F. Harvey,et al.  A SIMPLE INDEX OF CROHN'S-DISEASE ACTIVITY , 1980, The Lancet.

[46]  D. Parke,et al.  The metabolism of shikimate in the rat. , 1978, The Biochemical journal.

[47]  N. Benevenga,et al.  Significance of formate as an intermediate in the oxidation of the methionine, S-methyl-L-cysteine and sarcosine methyl carbons to CO2 in the rat. , 1977, The Journal of nutrition.

[48]  A. Tamm,et al.  The production of urinary phenols by gut bacteria and their possible role in the causation of large bowel cancer. , 1976, The American journal of clinical nutrition.

[49]  W. Denis,et al.  THE EXCRETION OF FREE AND CONJUGATED PHENOLS AND PHENOL DERIVATIVES , 1915 .