A novel method for the measurement of oxygen saturation in arterial blood

A novel and noninvasive method of estimation of oxygen saturation in arterial blood (SpO2), employing the popular photoelectric plethysmographic (PPG) principle, is presented here. Based on a refined model for the attenuation of light in a PPG sensor, a simple method of computation of SpO2 that is not influenced by interfering parameters of a patient such as skin colour and quantum of intervening tissue between the source and the detector in a PPG sensor as well as sensor dependent parameters such as source intensity and detector sensitivity is identified. Preliminary results obtained on a prototype pulse oximeter, built and tested, demonstrate the practicality of the proposed method.

[1]  Uday Shankar,et al.  Pulse oximetry theory and calibration for low saturations , 2004, IEEE Transactions on Biomedical Engineering.

[2]  John G. Webster,et al.  Design of Pulse Oximeters , 1997 .

[3]  L. Tarassenko,et al.  Pulse oximetry: Theoretical and experimental models , 2006, Medical and Biological Engineering and Computing.

[4]  B. George,et al.  A Novel Method of Measurement of Oxygen Saturation in Arterial Blood , 2008, 2008 IEEE Instrumentation and Measurement Technology Conference.

[5]  T. L. Rusch,et al.  Signal processing methods for pulse oximetry , 1996, Comput. Biol. Medicine.

[6]  J. Sinex.  Pulse oximetry: principles and limitations. , 1999, The American journal of emergency medicine.

[7]  A. B. Hertzman.  THE BLOOD SUPPLY OF VARIOUS SKIN AREAS AS ESTIMATED BY THE PHOTOELECTRIC PLETHYSMOGRAPH , 1938 .

[8]  Hanli Liu,et al.  Extinction coefficients of hemoglobin for near-infrared spectroscopy of tissue , 2005, IEEE Engineering in Medicine and Biology Magazine.

[9]  Y. Mendelson.  Pulse oximetry: theory and applications for noninvasive monitoring. , 1992, Clinical chemistry.

[10]  Gail D. Baura.  System Theory and Practical Applications of Biomedical Signals , 2002 .

[11]  J. Salyer,et al.  Neonatal and pediatric pulse oximetry. , 2003, Respiratory care.