Chromosomal instability drives metastasis through a cytosolic DNA response
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Samuel F. Bakhoum | Subramanian Venkatesan | Nancy Y. Lee | Giulio Genovese | Gouri Nanjangud | Charles Swanton | Jan Lammerding | Christine H Chung | Olivier Elemento | Ashley M. Laughney | Nicolai J. Birkbak | Dana Pe’er | Nicholas McGranahan | Lewis C. Cantley | John H. Healey | Peter Ly | D. Pe’er | O. Elemento | C. Swanton | L. Cantley | C. Chung | N. Birkbak | G. Genovese | J. Lammerding | S. Bakhoum | J. Healey | S. Venkatesan | S. Powell | G. Nanjangud | T. Watkins | K. Chadalavada | D. Cleveland | Q. LaPlant | Simon N. Powell | Don W. Cleveland | Quincey LaPlant | Vinagolu K. Rajasekhar | Bryan Ngo | Julie-Ann Cavallo | Charles J. Murphy | Pragya Shah | Roshan K Sriram | Thomas B. K. Watkins | Neil K. Taunk | Mercedes Duran | Chantal Pauli | Christine Shaw | Kalyani Chadalavada | Mark Lundquist | Marcin Imielenski | Charles J Murphy | C. Pauli | Pragya Shah | N. Taunk | B. Ngo | Christine J. Shaw | Roshan K. Sriram | Marcin Imielenski | N. Mcgranahan | P. Ly | N. Y. Lee | R. Sriram | J. Cavallo | Mercedes Durán | Mark Lundquist | Subramanian Venkatesan | Mercedes A Duran | Kalyani Chadalavada | Mercedes A. Duran | Vinagolu K Rajasekhar
[1] Z. Szallasi,et al. An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients , 2010, Breast Cancer Research and Treatment.
[2] T. Thai,et al. Cytosolic DNA-Activated Human Dendritic Cells Are Potent Activators of the Adaptive Immune Response , 2011, The Journal of Immunology.
[3] Robert T. Jones,et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. , 2015, Cancer discovery.
[4] L. Esserman,et al. A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer. , 2011, JAMA.
[5] O. Griffith,et al. Mitelman Database (Chromosome Aberrations and Gene Fusions in Cancer) , 2014 .
[6] J. Lammerding,et al. Nuclear Deformability Constitutes a Rate-Limiting Step During Cell Migration in 3-D Environments , 2014, Cellular and molecular bioengineering.
[7] William T. Silkworth,et al. The mitotic origin of chromosomal instability , 2014, Current Biology.
[8] S. Lowe,et al. Mad2 overexpression promotes aneuploidy and tumorigenesis in mice. , 2007, Cancer cell.
[9] Paolo Di Tommaso,et al. Nextflow enables reproducible computational workflows , 2017, Nature Biotechnology.
[10] S. Ems-McClung,et al. Kinesin-13s in mitosis: Key players in the spatial and temporal organization of spindle microtubules. , 2010, Seminars in cell & developmental biology.
[11] Zhijian J. Chen,et al. Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway , 2013, Science.
[12] Replication stress links structural and numerical cancer chromosomal instability (vol 494, pg 492, 2013) , 2013 .
[13] Nicolai J. Birkbak,et al. Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade , 2016, Science.
[14] Jan O. Korbel,et al. Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth , 2016, Cell reports.
[15] Elizabeth E Gray,et al. DNA tumor virus oncogenes antagonize the cGAS-STING DNA-sensing pathway , 2015, Science.
[16] Jeremy Wazny,et al. Xenome—a tool for classifying reads from xenograft samples , 2012, Bioinform..
[17] F. Mitelman,et al. Mitelman database of chromosome aberrations and gene fusions in cancer , 2014 .
[18] Cristina Montagna,et al. Aneuploidy acts both oncogenically and as a tumor suppressor. , 2007, Cancer cell.
[19] E. Salmon,et al. Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts , 1999, Nature Cell Biology.
[20] Prabhjot Kaur,et al. Chromosomal Instability Substantiates Poor Prognosis in Patients with Diffuse Large B-cell Lymphoma , 2011, Clinical Cancer Research.
[21] W. Huber,et al. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 , 2014, Genome Biology.
[22] N. Hacohen,et al. Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy. , 2014, Cell reports.
[23] Nicolai J. Birkbak,et al. Tracking the Evolution of Non‐Small‐Cell Lung Cancer , 2017, The New England journal of medicine.
[24] Helen Skaletsky,et al. Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining , 2016, Nature Cell Biology.
[25] Charles Swanton,et al. Metastasis as an evolutionary process , 2016, Science.
[26] Samuel F. Bakhoum,et al. Genome stability is ensured by temporal control of kinetochore-microtubule dynamics , 2008, Nature Cell Biology.
[27] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[28] Roland Eils,et al. circlize implements and enhances circular visualization in R , 2014, Bioinform..
[29] Angelika Amon,et al. Single-chromosome Gains Commonly Function as Tumor Suppressors. , 2017, Cancer cell.
[30] Cole Trapnell,et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.
[31] Y. Moreau,et al. Positional gene enrichment analysis of gene sets for high-resolution identification of overrepresented chromosomal regions , 2008, Nucleic acids research.
[32] S. Bakhoum,et al. Chromosomal instability portends superior response of rectal adenocarcinoma to chemoradiation therapy , 2014, Cancer.
[33] G. von Dassow,et al. MCAK associates with the tips of polymerizing microtubules , 2005, The Journal of cell biology.
[34] Jan Lammerding,et al. Nuclear envelope rupture and repair during cancer cell migration , 2016, Science.
[35] Robert J. Lonigro,et al. Integrative Clinical Genomics of Metastatic Cancer , 2017, Nature.
[36] Martin A. M. Reijns,et al. cGAS surveillance of micronuclei links genome instability to innate immunity , 2017, Nature.
[37] Zhijian J. Chen,et al. cGAS is essential for cellular senescence , 2017, Proceedings of the National Academy of Sciences.
[38] Shao-Cong Sun. Controlling the Fate of NIK: A Central Stage in Noncanonical NF-κB Signaling , 2010, Science Signaling.
[39] Jiri Bartek,et al. Replication stress links structural and numerical cancer chromosomal instability , 2013, Nature.
[40] G. Sonenshein,et al. Oestrogen signalling inhibits invasive phenotype by repressing RelB and its target BCL2 , 2007, Nature Cell Biology.
[41] K. Kaestner,et al. Cytoplasmic chromatin triggers inflammation in senescence and cancer , 2017, Nature.
[42] G. Barber,et al. Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF-κB Activation through TBK1 , 2014, Journal of Virology.
[43] Paul Theodor Pyl,et al. HTSeq—a Python framework to work with high-throughput sequencing data , 2014, bioRxiv.
[44] Alexey Khodjakov,et al. Merotelic Kinetochore Orientation Is a Major Mechanism of Aneuploidy in Mitotic Mammalian Tissue Cells , 2001, The Journal of cell biology.
[45] Jason M. Sheltzer,et al. A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis. , 2013, Cancer research.
[46] Jan Budczies,et al. Online Survival Analysis Software to Assess the Prognostic Value of Biomarkers Using Transcriptomic Data in Non-Small-Cell Lung Cancer , 2013, PloS one.
[47] J. Massagué,et al. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer , 2016, Nature.
[48] A. Villunger,et al. Signalling strength determines proapoptotic functions of STING , 2017, Nature Communications.
[49] Grace X. Y. Zheng,et al. Massively parallel digital transcriptional profiling of single cells , 2016, Nature Communications.
[50] Sean C. Bendall,et al. Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis , 2015, Cell.
[51] Kevin R. Moon,et al. MAGIC: A diffusion-based imputation method reveals gene-gene interactions in single-cell RNA-sequencing data , 2017, bioRxiv.
[52] Thomas R. Gingeras,et al. STAR: ultrafast universal RNA-seq aligner , 2013, Bioinform..
[53] C. Perou,et al. Molecular classification of head and neck squamous cell carcinomas using patterns of gene expression. , 2004, Cancer cell.
[54] T. Deerinck,et al. Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei , 2013, Cell.
[55] Dennis E Discher,et al. Mitotic progression following DNA damage enables pattern recognition within micronuclei , 2017, Nature.
[56] G. Barber,et al. Inflammation-driven carcinogenesis is mediated through STING , 2014, Nature Communications.
[57] R. Mach,et al. Antagonism of inhibitor of apoptosis proteins increases bone metastasis via unexpected osteoclast activation. , 2013, Cancer discovery.
[58] T. Heidmann,et al. Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity , 2008, Cell.
[59] Duane A. Compton,et al. Examining the link between chromosomal instability and aneuploidy in human cells , 2008, The Journal of cell biology.
[60] Ashley M. Laughney,et al. Numerical chromosomal instability mediates susceptibility to radiation treatment , 2015, Nature Communications.
[61] Jun Zhou,et al. The NF-κB subunit RelB regulates the migration and invasion abilities and the radio-sensitivity of prostate cancer cells. , 2016, International journal of oncology.