Evidence-based recommendations for optimal dietary protein intake in older people: a position paper from the PROT-AGE Study Group.

[1]  C. Wanner,et al.  Prevention and treatment of protein energy wasting in chronic kidney disease patients: a consensus statement by the International Society of Renal Nutrition and Metabolism. , 2013, Kidney international.

[2]  R. Wolfe,et al.  Effect of β-hydroxy-β-methylbutyrate (HMB) on lean body mass during 10 days of bed rest in older adults. , 2013, Clinical nutrition.

[3]  R. Fielding,et al.  Efficacy of whey protein supplementation on resistance exercise-induced changes in lean mass, muscle strength, and physical function in mobility-limited older adults. , 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

[4]  L. V. van Loon,et al.  Leucine co-ingestion improves post-prandial muscle protein accretion in elderly men. , 2013, Clinical nutrition.

[5]  R. Wolfe,et al.  Is the optimal level of protein intake for older adults greater than the recommended dietary allowance? , 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

[6]  M. Cesari,et al.  The stress of aging , 2013, Experimental Gerontology.

[7]  B. Hamon-Vilcot,et al.  Impact of protein pulse feeding on lean mass in malnourished and at-risk hospitalized elderly patients: a randomized controlled trial. , 2013, Clinical nutrition.

[8]  E. Volpi,et al.  Protein blend ingestion following resistance exercise promotes human muscle protein synthesis. , 2013, The Journal of nutrition.

[9]  R. Wolfe,et al.  Is there a maximal anabolic response to protein intake with a meal? , 2013, Clinical nutrition.

[10]  Chang-O Kim,et al.  Preventive effect of protein-energy supplementation on the functional decline of frail older adults with low socioeconomic status: a community-based randomized controlled study. , 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

[11]  G. Onder,et al.  Sarcopenia and mortality risk in frail older persons aged 80 years and older: results from ilSIRENTE study. , 2013, Age and ageing.

[12]  Pereira Suzette,et al.  β‐ヒドロキシ‐β‐酪酸メチル(HMB)が高齢者における10日間床上安静時の除脂肪体重に及ぼす影響 , 2013 .

[13]  Jacob M. Wilson,et al.  Efficacy of β-hydroxy-β-methylbutyrate supplementation in elderly and clinical populations. , 2013, Nutrition.

[14]  Kenneth Rockwood,et al.  Searching for an operational definition of frailty: a Delphi method based consensus statement: the frailty operative definition-consensus conference project. , 2013, The journals of gerontology. Series A, Biological sciences and medical sciences.

[15]  W. Saris,et al.  Protein supplementation augments the adaptive response of skeletal muscle to resistance-type exercise training: a meta-analysis. , 2012, The American journal of clinical nutrition.

[16]  M. Tarnopolsky,et al.  Resistance exercise enhances myofibrillar protein synthesis with graded intakes of whey protein in older men. , 2012, The British journal of nutrition.

[17]  Nathaniel Clark,et al.  Diabetes in Older Adults , 2012, Diabetes Care.

[18]  H. Sanada,et al.  Estimation of Protein Requirements According to Nitrogen Balance for Older Hospitalized Adults with Pressure Ulcers According to Wound Severity in Japan , 2012, Journal of the American Geriatrics Society.

[19]  L. D. de Groot,et al.  Protein supplementation improves physical performance in frail elderly people: a randomized, double-blind, placebo-controlled trial. , 2012, Journal of the American Medical Directors Association.

[20]  R. Hakim,et al.  Outcomes associated with intradialytic oral nutritional supplements in patients undergoing maintenance hemodialysis: a quality improvement report. , 2012, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[21]  L. D. de Groot,et al.  Protein supplementation increases muscle mass gain during prolonged resistance-type exercise training in frail elderly people: a randomized, double-blind, placebo-controlled trial. , 2012, Journal of the American Medical Directors Association.

[22]  H. Sauerwein,et al.  Protein recommendations in the ICU: g protein/kg body weight - which body weight for underweight and obese patients? , 2012, Clinical nutrition.

[23]  S. Berney,et al.  Early rehabilitation in critical care (eRiCC): functional electrical stimulation with cycling protocol for a randomised controlled trial , 2012, BMJ Open.

[24]  R. Marcus,et al.  Targeting Anabolic Impairment in Response to Resistance Exercise in Older Adults with Mobility Impairments: Potential Mechanisms and Rehabilitation Approaches , 2012, Journal of aging research.

[25]  B. Bistrian,et al.  Appropriate protein provision in critical illness: a systematic and narrative review. , 2012, The American journal of clinical nutrition.

[26]  R. R. Pillai,et al.  Amino acid requirements in children and the elderly population , 2012, British Journal of Nutrition.

[27]  R. Wolfe.  The role of dietary protein in optimizing muscle mass, function and health outcomes in older individuals , 2012, British Journal of Nutrition.

[28]  J. Woo,et al.  Comparison of Frailty Indicators Based on Clinical Phenotype and the Multiple Deficit Approach in Predicting Mortality and Physical Limitation , 2012, Journal of the American Geriatrics Society.

[29]  G. Schaafsma.  Advantages and limitations of the protein digestibility-corrected amino acid score (PDCAAS) as a method for evaluating protein quality in human diets , 2012, British Journal of Nutrition.

[30]  S. Walrand,et al.  Nutrition, Protein Turnover and Muscle Mass , 2012, Sarcopenia.

[31]  D. Paddon-Jones,et al.  Nutritional Approaches to Treating Sarcopenia , 2012 .

[32]  Ate Dijkstra,et al.  Health and nursing problems of elderly patients related to bio-psycho-social need deficiencies and functional assessment. , 2012, Archives of gerontology and geriatrics.

[33]  L. Denehy,et al.  Exercise rehabilitation following hospital discharge in survivors of critical illness: an integrative review , 2012, Critical Care.

[34]  M. Tarnopolsky,et al.  Myofibrillar protein synthesis following ingestion of soy protein isolate at rest and after resistance exercise in elderly men , 2012, Nutrition & Metabolism.

[35]  E. Volpi,et al.  A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults. , 2012, The American journal of clinical nutrition.

[36]  M. Hunt,et al.  Exercise prescription for hospitalized people with chronic obstructive pulmonary disease and comorbidities: a synthesis of systematic reviews , 2012, International journal of chronic obstructive pulmonary disease.

[37]  M. Elia,et al.  Systematic review and meta-analysis of the effects of high protein oral nutritional supplements , 2012, Ageing Research Reviews.

[38]  J. Seidell,et al.  Oral nutritional support in malnourished elderly decreases functional limitations with no extra costs. , 2012, Clinical nutrition.

[39]  Edgar Pierluissi,et al.  Attitudes and Expectations Regarding Exercise in the Hospital of Hospitalized Older Adults: A Qualitative Study , 2012, Journal of the American Geriatrics Society.

[40]  I. Vasileiadis,et al.  Electrical Muscle Stimulation: An Effective Form of Exercise and Early Mobilization to Preserve Muscle Strength in Critically Ill Patients , 2012, Critical care research and practice.

[41]  M. Tarnopolsky,et al.  Greater stimulation of myofibrillar protein synthesis with ingestion of whey protein isolate v. micellar casein at rest and after resistance exercise in elderly men. , 2012, The British journal of nutrition.

[42]  L. V. van Loon.  Leucine as a pharmaconutrient in health and disease , 2012, Current opinion in clinical nutrition and metabolic care.

[43]  Hisamine Kobayashi,et al.  Effects of Exercise and Amino Acid Supplementation on Body Composition and Physical Function in Community‐Dwelling Elderly Japanese Sarcopenic Women: A Randomized Controlled Trial , 2012, Journal of the American Geriatrics Society.

[44]  L. Loon.  Leucine as a pharmaconutrient in health and disease , 2012 .

[45]  菅原 慶勇.  Effects of nutritional supplementation combined with low-intensity exercise in malnourished patients with COPD , 2012 .

[46]  Albertus Beishuizen,et al.  Optimal protein and energy nutrition decreases mortality in mechanically ventilated, critically ill patients: a prospective observational cohort study. , 2012, JPEN. Journal of parenteral and enteral nutrition.

[47]  M. Inzitari,et al.  Nutrition in the age-related disablement process , 2011, The journal of nutrition, health & aging.

[48]  A. Dewey.  Nutritional supplementation for hip fracture aftercare in older people. , 2011, International journal of older people nursing.

[49]  A. Malpica,et al.  Guidelines for specialized nutritional and metabolic support in the critically-ill patient. Update. Consensus SEMICYUC-SENPE: Cardiac patient , 2011 .

[50]  J. Paratz,et al.  Early rehabilitation in sepsis: a prospective randomised controlled trial investigating functional and physiological outcomes The i-PERFORM Trial (Protocol Article) , 2011, BMC anesthesiology.

[51]  T. Nestares,et al.  Influence of cow or goat milk consumption on antioxidant defence and lipid peroxidation during chronic iron repletion , 2011, British Journal of Nutrition.

[52]  P. Chauveau,et al.  Nutrition and chronic kidney disease. , 2011, Kidney international.

[53]  S. Walrand,et al.  Physiopathological mechanism of sarcopenia. , 2011, Clinics in geriatric medicine.

[54]  A. LaCroix,et al.  Higher biomarker-calibrated protein intake is not associated with impaired renal function in postmenopausal women. , 2011, The Journal of nutrition.

[55]  Y. Boirie,et al.  Toward a definition of sarcopenia. , 2011, Clinics in geriatric medicine.

[56]  M. Visser,et al.  Predictors for achieving protein and energy requirements in undernourished hospital patients. , 2011, Clinical nutrition.

[57]  Yu-fei Li,et al.  Sarcopenia , 2011 .

[58]  S. Muurinen,et al.  Nutritional status, energy, protein, and micronutrient intake of older service house residents. , 2011, Journal of the American Medical Directors Association.

[59]  H. Kuipers,et al.  Whey protein stimulates postprandial muscle protein accretion more effectively than do casein and casein hydrolysate in older men. , 2011, The American journal of clinical nutrition.

[60]  A. Lucia,et al.  Short‐Term, Light‐ to Moderate‐Intensity Exercise Training Improves Leg Muscle Strength in the Oldest Old: A Randomized Controlled Trial , 2011, Journal of the American Geriatrics Society.

[61]  M. Rennie,et al.  Enhanced amino acid sensitivity of myofibrillar protein synthesis persists for up to 24 h after resistance exercise in young men. , 2011, The Journal of nutrition.

[62]  T. Reinhold,et al.  Cost-effectiveness of a 3-month intervention with oral nutritional supplements in disease-related malnutrition: a randomised controlled pilot study , 2011, European Journal of Clinical Nutrition.

[63]  A. Venezia,et al.  Use of creatine in the elderly and evidence for effects on cognitive function in young and old , 2011, Amino Acids.

[64]  D. Candow.  Sarcopenia: current theories and the potential beneficial effect of creatine application strategies , 2011, Biogerontology.

[65]  N. Deutz,et al.  Differential metabolic effects of casein and soy protein meals on skeletal muscle in healthy volunteers. , 2011, Clinical nutrition.

[66]  D. O’Mahony,et al.  The Barthel Index: comparing inter-rater reliability between nurses and doctors in an older adult rehabilitation unit. , 2011, Applied nursing research : ANR.

[67]  D. Reeds,et al.  Dietary omega-3 fatty acid supplementation increases the rate of muscle protein synthesis in older adults: a randomized controlled trial. , 2011, The American journal of clinical nutrition.

[68]  A. B. Blesa Malpica,et al.  Guidelines for specialized nutritional and metabolic support in the critically-ill patient: update. Consensus SEMICYUC-SENPE: cardiac patient. , 2011, Nutricion hospitalaria.

[69]  N. Kristensen,et al.  Whey and casein labeled with L-[1-13C]leucine and muscle protein synthesis: effect of resistance exercise and protein ingestion. , 2011, American journal of physiology. Endocrinology and metabolism.

[70]  J. Shaw,et al.  The effect of high-protein, low-carbohydrate diets in the treatment of type 2 diabetes: a 12 month randomised controlled trial , 2011, Diabetologia.

[71]  R. Koopman.  Dietary protein and exercise training in ageing , 2010, Proceedings of the Nutrition Society.

[72]  G. Giles,et al.  Associations Between Dietary Nutrient Intake and Muscle Mass and Strength in Community‐Dwelling Older Adults: The Tasmanian Older Adult Cohort Study , 2010, Journal of the American Geriatrics Society.

[73]  F. Arrieta,et al.  Perioperative oral nutritional supplements in normally or mildly undernourished geriatric patients submitted to surgery for hip fracture: a randomized clinical trial. , 2010, Clinical nutrition.

[74]  E. Melanson,et al.  Nitrogen balance in older individuals in energy balance depends on timing of protein intake. , 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.

[75]  L. Martini,et al.  Effect of protein intake on bone and muscle mass in the elderly. , 2010, Nutrition reviews.

[76]  L. Ferrucci,et al.  Nutritional recommendations for the management of sarcopenia. , 2010, Journal of the American Medical Directors Association.

[77]  G. Hankey,et al.  Low free testosterone predicts frailty in older men: the health in men study. , 2010, The Journal of clinical endocrinology and metabolism.

[78]  F. Maltais,et al.  Combined effect of dietary supplementation with pressurized whey and exercise training in chronic obstructive pulmonary disease: a randomized, controlled, double-blind pilot study. , 2010, Journal of medicinal food.

[79]  J. Kerstetter,et al.  Optimizing bone health in older adults: the importance of dietary protein. , 2010, Aging health.

[80]  M. Hoogendoorn,et al.  Efficacy and costs of nutritional rehabilitation in muscle-wasted patients with chronic obstructive pulmonary disease in a community-based setting: a prespecified subgroup analysis of the INTERCOM trial. , 2010, Journal of the American Medical Directors Association.

[81]  R. Aquilani,et al.  Comprehensive effects of supplemented essential amino acids in patients with severe COPD and sarcopenia. , 2010, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace.

[82]  R. Wolfe,et al.  EAA supplementation to increase nitrogen intake improves muscle function during bed rest in the elderly. , 2010, Clinical nutrition.

[83]  M. Bemben,et al.  The effects of supplementation with creatine and protein on muscle strength following a traditional resistance training program in middle-aged and older men , 2010, The journal of nutrition, health & aging.

[84]  P. Chilibeck,et al.  Potential of creatine supplementation for improving aging bone health , 2010, The journal of nutrition, health & aging.

[85]  Kirk L English,et al.  Protecting muscle mass and function in older adults during bed rest , 2010, Current opinion in clinical nutrition and metabolic care.

[86]  A. LaCroix,et al.  Protein Intake and Incident Frailty in the Women's Health Initiative Observational Study , 2010, Journal of the American Geriatrics Society.

[87]  D. Nemet,et al.  Effect of HMB Supplementation on Body Composition, Fitness, Hormonal Profile and Muscle Damage Indices , 2010, Journal of pediatric endocrinology & metabolism : JPEM.

[88]  J. Baeyens,et al.  European working group on sarcopenia in older people. Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people , 2010 .

[89]  Vincent W Vanek,et al.  Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). , 2016, JPEN. Journal of parenteral and enteral nutrition.

[90]  S. Lanham-New,et al.  Dietary protein and bone health: a systematic review and meta-analysis. , 2009, The American journal of clinical nutrition.

[91]  T. Kornatowski,et al.  Functional assessment and health-related quality of life (HRQOL) of elderly patients on the basis of the functional assessment of chronic illness therapy (FACIT)-F questionnaire. , 2009, Archives of gerontology and geriatrics.

[92]  D. Kerr,et al.  A 5‐Year Cohort Study of the Effects of High Protein Intake on Lean Mass and BMC in Elderly Postmenopausal Women , 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[93]  M. Rennie,et al.  Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia. , 2009, The American journal of clinical nutrition.

[94]  W. Saris,et al.  Dietary protein digestion and absorption rates and the subsequent postprandial muscle protein synthetic response do not differ between young and elderly men. , 2009, The Journal of nutrition.

[95]  Thierry Troosters,et al.  Early exercise in critically ill patients enhances short-term functional recovery* , 2009, Critical care medicine.

[96]  Y. Tomino,et al.  Long-term effect of modification of dietary protein intake on the progression of diabetic nephropathy: a randomised controlled trial , 2009, Diabetologia.

[97]  Stuart M Phillips,et al.  The Role of Milk- and Soy-Based Protein in Support of Muscle Protein Synthesis and Muscle Protein Accretion in Young and Elderly Persons , 2009, Journal of the American College of Nutrition.

[98]  Nancy K Latham,et al.  Progressive resistance strength training for improving physical function in older adults. , 2009, The Cochrane database of systematic reviews.

[99]  S. Berney,et al.  Development of a physical function outcome measure (PFIT) and a pilot exercise training protocol for use in intensive care. , 2009, Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine.

[100]  N. Rodriguez,et al.  Increasing Dietary Protein Requirements in Elderly People for Optimal Muscle and Bone Health , 2009, Journal of the American Geriatrics Society.

[101]  D. Buchner,et al.  The prescribed amount of physical activity in randomized clinical trials in older adults. , 2009, The Gerontologist.

[102]  D. Rowlands,et al.  Effects of β-Hydroxy-β-Methylbutyrate Supplementation During Resistance Training on Strength, Body Composition, and Muscle Damage in Trained and Untrained Young Men: A Meta-Analysis , 2009, Journal of strength and conditioning research.

[103]  L. V. van Loon,et al.  Long-term leucine supplementation does not increase muscle mass or strength in healthy elderly men. , 2009, The American journal of clinical nutrition.

[104]  A. Avenell,et al.  Protein and energy supplementation in elderly people at risk from malnutrition. , 2009, The Cochrane database of systematic reviews.

[105]  Stuart M Phillips,et al.  Maximizing muscle protein anabolism: the role of protein quality , 2009, Current opinion in clinical nutrition and metabolic care.

[106]  B. Rasmussen,et al.  Dietary protein recommendations and the prevention of sarcopenia , 2009, Current opinion in clinical nutrition and metabolic care.

[107]  A. Forbes,et al.  ESPEN Guidelines on Parenteral Nutrition: intensive care. , 2006, Clinical nutrition.

[108]  P. Flakoll,et al.  Year-long changes in protein metabolism in elderly men and women supplemented with a nutrition cocktail of beta-hydroxy-beta-methylbutyrate (HMB), L-arginine, and L-lysine. , 2009, JPEN. Journal of parenteral and enteral nutrition.

[109]  Medical Advisory Secretariat.  Management of chronic pressure ulcers: an evidence-based analysis. , 2009, Ontario health technology assessment series.

[110]  Timothy J. Brennan,et al.  Early physical and occupational therapy in mechanically ventilated , critically ill patients : A randomised controlled trial , 2009 .

[111]  D. Chinkes,et al.  Whey protein ingestion in elderly persons results in greater muscle protein accrual than ingestion of its constituent essential amino acid content. , 2008, Nutrition research.

[112]  R. Wolfe,et al.  Optimal protein intake in the elderly. , 2008, Clinical nutrition.

[113]  P. D. di Prampero,et al.  Positive energy balance is associated with accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest. , 2008, The American journal of clinical nutrition.

[114]  S. Cornish,et al.  Low-dose creatine combined with protein during resistance training in older men. , 2008, Medicine and science in sports and exercise.

[115]  G. Gambaro,et al.  Treating elderly people with diabetes and stages 3 and 4 chronic kidney disease. , 2008, Clinical journal of the American Society of Nephrology : CJASN.

[116]  C. Pison,et al.  Impact of nutritional status on body functioning in chronic obstructive pulmonary disease and how to intervene , 2008, Current opinion in clinical nutrition and metabolic care.

[117]  C. Opasich,et al.  Oral amino acid supplements improve exercise capacities in elderly patients with chronic heart failure. , 2008, The American journal of cardiology.

[118]  P. Ritz,et al.  Are Elderly Hospitalized Patients Getting Enough Protein? , 2008, Journal of the American Geriatrics Society.

[119]  V. Fulgoni.  Current protein intake in America: analysis of the National Health and Nutrition Examination Survey, 2003-2004. , 2008, The American journal of clinical nutrition.

[120]  B. Haraldsson,et al.  Positive effects of protein restriction in patients with chronic kidney disease. , 2008, Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.

[121]  S. Scharf,et al.  Nutritional aspects of chronic obstructive pulmonary disease. , 2008, Proceedings of the American Thoracic Society.

[122]  D. Tomé,et al.  Protein quality assessment: impact of expanding understanding of protein and amino acid needs for optimal health. , 2008, The American journal of clinical nutrition.

[123]  P. Freedson,et al.  Amount of time spent in sedentary behaviors in the United States, 2003-2004. , 2008, American journal of epidemiology.

[124]  H. Lochs,et al.  Three month intervention with protein and energy rich supplements improve muscle function and quality of life in malnourished patients with non-neoplastic gastrointestinal disease--a randomized controlled trial. , 2008, Clinical nutrition.

[125]  S. Studenski,et al.  Functional outcomes for clinical trials in frail older persons: time to be moving. , 2008, The journals of gerontology. Series A, Biological sciences and medical sciences.

[126]  Y. Rolland,et al.  Frailty: toward a clinical definition. , 2008, Journal of the American Medical Directors Association.

[127]  M. Tarnopolsky,et al.  The potential benefits of creatine and conjugated linoleic acid as adjuncts to resistance training in older adults. , 2008, Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.

[128]  E. Volpi,et al.  Amino acid metabolism and regulatory effects in aging , 2008, Current opinion in clinical nutrition and metabolic care.

[129]  F. Schmidt.  Meta-Analysis , 2008 .

[130]  D. Houston,et al.  Dietary protein intake is associated with lean mass change in older, community-dwelling adults: the Health, Aging, and Body Composition (Health ABC) Study. , 2008, The American journal of clinical nutrition.

[131]  W. Campbell,et al.  Dietary Protein and Resistance Training Effects on Muscle and Body Composition in Older Persons , 2007, Journal of the American College of Nutrition.

[132]  N. Waugh,et al.  Protein restriction for diabetic renal disease. , 2007, The Cochrane database of systematic reviews.

[133]  T. Trappe,et al.  Influence of concurrent exercise or nutrition countermeasures on thigh and calf muscle size and function during 60 days of bed rest in women , 2007, Acta physiologica.

[134]  T. Cederholm,et al.  Effects of protein-rich supplementation and nandrolone on bone tissue after a hip fracture. , 2007, Clinical nutrition.

[135]  M. Aparicio,et al.  Eleven reasons to control the protein intake of patients with chronic kidney disease , 2007, Nature Clinical Practice Nephrology.

[136]  S. Fujita,et al.  Aerobic Exercise Overcomes the Age-Related Insulin Resistance of Muscle Protein Metabolism by Improving Endothelial Function and Akt/Mammalian Target of Rapamycin Signaling , 2007, Diabetes.

[137]  B. F. Viola,et al.  Efficacy and safety of a very-low-protein diet when postponing dialysis in the elderly: a prospective randomized multicenter controlled study. , 2007, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[138]  Walter R Frontera,et al.  Is stair climb power a clinically relevant measure of leg power impairments in at-risk older adults? , 2007, Archives of physical medicine and rehabilitation.

[139]  T. Strandberg,et al.  Frailty in elderly people , 2007, The Lancet.

[140]  D. Candow,et al.  Effect of creatine supplementation during resistance training on muscle accretion in the elderly. , 2007, The journal of nutrition, health & aging.

[141]  Kdoqi.  KDOQI Clinical Practice Guidelines and Clinical Practice Recommendations for Diabetes and Chronic Kidney Disease. , 2007, American journal of kidney diseases : the official journal of the National Kidney Foundation.

[142]  Joint Fao Who Consultation.  Protein and amino acid requirements in human nutrition. , 2007, World Health Organization technical report series.

[143]  I. Rieu,et al.  Leucine supplementation improves muscle protein synthesis in elderly men independently of hyperaminoacidaemia , 2006, The Journal of physiology.

[144]  R. Wolfe,et al.  A high proportion of leucine is required for optimal stimulation of the rate of muscle protein synthesis by essential amino acids in the elderly. , 2006, American journal of physiology. Endocrinology and metabolism.

[145]  B. Killey,et al.  The effect of extra walking on the mobility, independence and exercise self-efficacy of elderly hospital in-patients: A pilot study , 2006, Contemporary nurse.

[146]  R. Gougeon,et al.  Protein turnover and requirements in the healthy and frail elderly. , 2006, The journal of nutrition, health & aging.

[147]  S. Studenski,et al.  Association of long-distance corridor walk performance with mortality, cardiovascular disease, mobility limitation, and disability. , 2006, JAMA.

[148]  G. Biolo,et al.  Response of muscle protein and glutamine kinetics to branched-chain-enriched amino acids in intensive care patients after radical cancer surgery. , 2006, Nutrition.

[149]  R. Teasell,et al.  Energy and protein intakes of acute stroke patients. , 2006, The journal of nutrition, health & aging.

[150]  M. Crotty,et al.  Lower limb fracture, cognitive impairment and risk of subsequent malnutrition: a prospective evaluation of dietary energy and protein intake on an orthopaedic ward , 2006, European Journal of Clinical Nutrition.

[151]  R. Wolfe,et al.  Differential stimulation of muscle protein synthesis in elderly humans following isocaloric ingestion of amino acids or whey protein , 2006, Experimental Gerontology.

[152]  Graham Lawton,et al.  Get up and go , 2006 .

[153]  M. Berger,et al.  Nutritional status and food intake in nine patients with chronic low-limb ulcers and pressure ulcers: importance of oral supplements. , 2006, Nutrition.

[154]  D. Attaix,et al.  Altered responses in skeletal muscle protein turnover during aging in anabolic and catabolic periods. , 2005, The international journal of biochemistry & cell biology.

[155]  Lawrence E Armstrong,et al.  Dietary protein intake and renal function , 2005, Nutrition & metabolism.

[156]  S. Dhaliwal,et al.  Protein consumption is an important predictor of lower limb bone mass in elderly women. , 2005, The American journal of clinical nutrition.

[157]  M. Mcmurdo,et al.  Nutritional Supplementation of Very Old People at Hospital Discharge Increases Muscle Strength: A Randomised Controlled Trial , 2005, Gerontology.

[158]  R. Wolfe,et al.  The catabolic effects of prolonged inactivity and acute hypercortisolemia are offset by dietary supplementation. , 2005, The Journal of clinical endocrinology and metabolism.

[159]  S. Walrand,et al.  Optimizing protein intake in aging , 2005, Current opinion in clinical nutrition and metabolic care.

[160]  Cynthia D. Brown,et al.  Minimal Clinically Important Differences in the Six-Minute Walk Test and the Incremental Shuttle Walking Test , 2005, COPD.

[161]  R. Chernoff.  Protein and Older Adults , 2004, Journal of the American College of Nutrition.

[162]  W. Evans.  Protein Nutrition, Exercise and Aging , 2004, Journal of the American College of Nutrition.

[163]  P. Gachon,et al.  Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humans , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[164]  R. Wolfe,et al.  Essential amino acid and carbohydrate supplementation ameliorates muscle protein loss in humans during 28 days bedrest. , 2004, The Journal of clinical endocrinology and metabolism.

[165]  K. Brismar,et al.  Effects of protein-rich supplementation and nandrolone in lean elderly women with femoral neck fractures. , 2004, Clinical nutrition.

[166]  P. Stehle,et al.  What are the essential elements needed for the determination of amino acid requirements in humans? , 2004, The Journal of nutrition.

[167]  H. Rasmussen,et al.  Effect of dietary protein supplements on calcium excretion in healthy older men and women. , 2004, The Journal of clinical endocrinology and metabolism.

[168]  R. Wolfe,et al.  Amino acid ingestion improves muscle protein synthesis in the young and elderly. , 2004, American journal of physiology. Endocrinology and metabolism.

[169]  Ronenn Roubenoff,et al.  The Healthcare Costs of Sarcopenia in the United States , 2004, Journal of the American Geriatrics Society.

[170]  Thomas R. Riley,et al.  A Randomized Double-blind Placebo-controlled Trial , 2004 .

[171]  S. Allison,et al.  Basics in Clinical Nutrition , 2004 .

[172]  O. Beauchet,et al.  Energy and nutrient intake of elderly hospitalized patients in a steady metabolic status versus catabolic status. , 2004, The journal of nutrition, health & aging.

[173]  Y. Boirie,et al.  Daily protein intakes and eating patterns in young and elderly French , 2003, British Journal of Nutrition.

[174]  R. Gougeon,et al.  Frailty amplifies the effects of aging on protein metabolism: role of protein intake. , 2003, The American journal of clinical nutrition.

[175]  M. Steiner,et al.  Nutritional enhancement of exercise performance in chronic obstructive pulmonary disease: a randomised controlled trial , 2003, Thorax.

[176]  M. Rantz,et al.  Integrative Review of Physical Activity Intervention Research with Aging Adults , 2003, Journal of the American Geriatrics Society.

[177]  R. Dom,et al.  Effects of creatine supplementation and exercise training on fitness in men 55-75 yr old. , 2003, Journal of applied physiology.

[178]  B. Beaufrère,et al.  The Rate of Protein Digestion affects Protein Gain Differently during Aging in Humans , 2003, The Journal of physiology.

[179]  J. Gallagher,et al.  Protein intake: effects on bone mineral density and the rate of bone loss in elderly women. , 2003, The American journal of clinical nutrition.

[180]  D. Spiegelman,et al.  The Impact of Protein Intake on Renal Function Decline in Women with Normal Renal Function or Mild Renal Insufficiency , 2003, Annals of Internal Medicine.

[181]  R. Sharp,et al.  Effect of dietary supplements on lean mass and strength gains with resistance exercise: a meta‐analysis , 2003, Journal of applied physiology.

[182]  M. Regan,et al.  Daily methionine requirements of healthy Indian men, measured by a 24-h indicator amino acid oxidation and balance technique. , 2003, The American journal of clinical nutrition.

[183]  Gianni Parise,et al.  Creatine supplementation enhances isometric strength and body composition improvements following strength exercise training in older adults. , 2003, The journals of gerontology. Series A, Biological sciences and medical sciences.

[184]  W. Rand,et al.  Meta-analysis of nitrogen balance studies for estimating protein requirements in healthy adults. , 2003, The American journal of clinical nutrition.

[185]  A. Donker,et al.  Protein restriction, glomerular filtration rate and albuminuria in patients with type 2 diabetes mellitus: a randomized trial , 2002, European Journal of Clinical Nutrition.

[186]  B. Beaufrère,et al.  Influence of the protein digestion rate on protein turnover in young and elderly subjects. , 2002, The Journal of nutrition.

[187]  Hélène Payette,et al.  Benefits of nutritional supplementation in free-living, frail, undernourished elderly people: a prospective randomized community trial. , 2002, Journal of the American Dietetic Association.

[188]  C. Casciani,et al.  Severe dietary protein restriction in overt diabetic nephropathy: benefits or risks? , 2002, Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.

[189]  E. Barrett-Connor,et al.  Protein consumption and bone mineral density in the elderly : the Rancho Bernardo Study. , 2002, American journal of epidemiology.

[190]  Arshag D Mooradian,et al.  Evidence-based nutrition principles and recommendations for the treatment and prevention of diabetes and related complications. , 2002, Diabetes care.

[191]  K. Chad,et al.  Creatine supplementation combined with resistance training in older men. , 2001, Medicine and science in sports and exercise.

[192]  Christianna S. Williams,et al.  Functional disability and health care expenditures for older persons. , 2001, Archives of internal medicine.

[193]  J. Reilly,et al.  Protein energy supplements in unwell elderly patients--a randomized controlled trial. , 2001, JPEN. Journal of parenteral and enteral nutrition.

[194]  W. Evans,et al.  Protein requirement of elderly women: nitrogen balance responses to three levels of protein intake. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

[195]  M. Kjaer,et al.  Timing of postexercise protein intake is important for muscle hypertrophy with resistance training in elderly humans , 2001, The Journal of physiology.

[196]  J. Wilczak,et al.  Creatine and β-hydroxy-β-methylbutyrate (HMB) additively increase lean body mass and muscle strength during a weight-training program ☆ , 2001 .

[197]  M. Vukovich,et al.  Body Composition in 70-Year-Old Adults Responds to Dietary β-Hydroxy-β-Methylbutyrate Similarly to That of Young Adults , 2001 .

[198]  T. Cederholm,et al.  Treatment of protein-energy malnutrition in chronic nonmalignant disorders. , 2001, The American journal of clinical nutrition.

[199]  R. Wolfe,et al.  The recommended dietary allowance for protein may not be adequate for older people to maintain skeletal muscle. , 2001, The journals of gerontology. Series A, Biological sciences and medical sciences.

[200]  P. Ritz,et al.  Differential insulin sensitivities of glucose, amino acid, and albumin metabolism in elderly men and women. , 2001, The Journal of clinical endocrinology and metabolism.

[201]  B. Beaufrère,et al.  The digestion rate of protein is an independent regulating factor of postprandial protein retention. , 2001, American journal of physiology. Endocrinology and metabolism.

[202]  K. Hauer,et al.  Exercise Training for Rehabilitation and Secondary Prevention of Falls in Geriatric Patients with a History of Injurious Falls , 2001, Journal of the American Geriatrics Society.

[203]  J. Wilczak,et al.  Creatine and beta-hydroxy-beta-methylbutyrate (HMB) additively increase lean body mass and muscle strength during a weight-training program. , 2001, Nutrition.

[204]  M. Vukovich,et al.  Body composition in 70-year-old adults responds to dietary beta-hydroxy-beta-methylbutyrate similarly to that of young adults. , 2001, The Journal of nutrition.

[205]  D. Kiel,et al.  Effect of Dietary Protein on Bone Loss in Elderly Men and Women: The Framingham Osteoporosis Study , 2000, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[206]  R. Wolfe,et al.  The response of muscle protein anabolism to combined hyperaminoacidemia and glucose-induced hyperinsulinemia is impaired in the elderly. , 2000, The Journal of clinical endocrinology and metabolism.

[207]  S. Baier,et al.  Nutritional supplementation of the leucine metabolite β-hydroxy-β-methylbutyrate (hmb) during resistance training , 2000 .

[208]  P. Reeds,et al.  Dispensable and indispensable amino acids for humans. , 2000, The Journal of nutrition.

[209]  H. Handoll,et al.  Nutritional supplementation for hip fracture aftercare in the elderly. , 2000, The Cochrane database of systematic reviews.

[210]  A. Kurpad,et al.  Protein and amino acid requirements in the elderly , 2000, European journal of clinical nutrition.

[211]  R. Ross,et al.  Distribution of protein turnover changes with age in humans as assessed by whole-body magnetic resonance image analysis to quantify tissue volumes. , 2000, The Journal of nutrition.

[212]  Suzanne G. Leveille,et al.  Lower extremity function and subsequent disability: consistency across studies, predictive models, and value of gait speed alone compared with the short physical performance battery. , 2000, The journals of gerontology. Series A, Biological sciences and medical sciences.

[213]  J. Kerstetter,et al.  Low Dietary Protein and Low Bone Density , 2000, Calcified Tissue International.

[214]  S. Baier,et al.  Nutritional supplementation of the leucine metabolite beta-hydroxy-beta-methylbutyrate (hmb) during resistance training. , 2000, Nutrition.

[215]  R. Wolfe,et al.  Oral amino acids stimulate muscle protein anabolism in the elderly despite higher first-pass splanchnic extraction. , 1999, The American journal of physiology.

[216]  P. Ritz,et al.  Protein pulse feeding improves protein retention in elderly women. , 1999, The American journal of clinical nutrition.

[217]  R. Beyth,et al.  The Relationship Between Clinical Assessments of Nutritional Status and Adverse Outcomes in Older Hospitalized Medical Patients , 1999, Journal of the American Geriatrics Society.

[218]  K. Westerterp,et al.  Effect of protein source and quantity on protein metabolism in elderly women. , 1998, The American journal of clinical nutrition.

[219]  R. Ball,et al.  Determination of amino acid requirements by indicator amino acid oxidation: applications in health and disease. , 1998, Current opinion in clinical nutrition and metabolic care.

[220]  R. Rizzoli,et al.  Protein Supplements Increase Serum Insulin-Like Growth Factor-I Levels and Attenuate Proximal Femur Bone Loss in Patients with Recent Hip Fracture , 1998, Annals of Internal Medicine.

[221]  A. Srivatsa,et al.  An initial assessment, using 24-h [13C]leucine kinetics, of the lysine requirement of healthy adult Indian subjects. , 1998, The American journal of clinical nutrition.

[222]  Daniel L. Feeback,et al.  Impact of resistance exercise during bed rest on skeletal muscle sarcopenia and myosin isoform distribution. , 1998, Journal of applied physiology.

[223]  B. Beaufrère,et al.  Slow and fast dietary proteins differently modulate postprandial protein accretion. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[224]  A. Levey,et al.  Effect of dietary protein restriction on nutritional status in the Modification of Diet in Renal Disease Study. , 1997, Kidney international.

[225]  G. Biolo,et al.  An abundant supply of amino acids enhances the metabolic effect of exercise on muscle protein. , 1997, The American journal of physiology.

[226]  P J Garry,et al.  Changes in nutritional status and patterns of morbidity among free-living elderly persons: a 10-year longitudinal study. , 1997, Nutrition.

[227]  R. Wolfe,et al.  Resistance exercise maintains skeletal muscle protein synthesis during bed rest. , 1997, Journal of applied physiology.

[228]  B. Beaufrère,et al.  Splanchnic and whole-body leucine kinetics in young and elderly men. , 1997, The American journal of clinical nutrition.

[229]  D. Volkert,et al.  Nutritional support and functional status in undernourished geriatric patients during hospitalization and 6-month follow-up , 1996, Aging.

[230]  M. Pratt,et al.  Physical activity and health , 1996, BMJ.

[231]  H. Payette,et al.  Randomized clinical trial of nutritional supplementation shows little effect on functional status among free-living frail elderly. , 1995, The Journal of nutrition.

[232]  R. Fielding,et al.  Effects of exercise training in the elderly: impact of progressive-resistance training on skeletal muscle and whole-body protein metabolism , 1995, Proceedings of the Nutrition Society.

[233]  M. C. Crim,et al.  Protein turnover and energy metabolism of elderly women fed a low-protein diet. , 1995, The American journal of clinical nutrition.

[234]  S. Stone,et al.  The Barthel Index in Clinical Practice: Use on a Rehabilitation Ward for Elderly People , 1994, Journal of the Royal College of Physicians of London.

[235]  S B Roberts,et al.  Exercise training and nutritional supplementation for physical frailty in very elderly people. , 1994, The New England journal of medicine.

[236]  G. Beck,et al.  The Effects of Dietary Protein Restriction and Blood-Pressure Control on the Progression of Chronic Renal Disease , 1994 .

[237]  L. Ferrucci,et al.  A short physical performance battery assessing lower extremity function: association with self-reported disability and prediction of mortality and nursing home admission. , 1994, Journal of gerontology.

[238]  G. Beck,et al.  The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group. , 1994, The New England journal of medicine.

[239]  H. Rodgers,et al.  Standardized functional assessment scales for elderly patients. , 1993, Age and ageing.

[240]  L. Lipsitz,et al.  High-intensity strength training in nonagenarians. Effects on skeletal muscle. , 1990, JAMA.

[241]  M. Rennie,et al.  PREVENTION OF DISUSE MUSCLE ATROPHY BY MEANS OF ELECTRICAL STIMULATION: MAINTENANCE OF PROTEIN SYNTHESIS , 1988, The Lancet.

[242]  S. Spiro,et al.  The effect of supplementary oral nutrition in poorly nourished patients with chronic obstructive pulmonary disease. , 1988, The American review of respiratory disease.

[243]  C. W. Wrigley,et al.  Proteins and amino acids , 1988 .

[244]  U S Nayak,et al.  Balance in elderly patients: the "get-up and go" test. , 1986, Archives of physical medicine and rehabilitation.

[245]  G. Marchesini,et al.  Anticatabolic Effect of Branched‐Chain Amino Acid‐Enriched Solutions in Patients with Liver Cirrhosis , 2007, Hepatology.

[246]  H. E. Jones,et al.  Letter: Splenectomy in acute lymphatic leukaemia. , 1975, Lancet.

[247]  M. Lawton.  THE FUNCTIONAL ASSESSMENT OF ELDERLY PEOPLE , 1971, Journal of the American Geriatrics Society.

[248]  S. Katz,et al.  Progress in development of the index of ADL. , 1970, The Gerontologist.

[249]  Waterlow Jc.  Lysine turnover in man measured by intravenous infusion of L-[U-14C]lysine. , 1967 .

[250]  J. Waterlow.  Lysine turnover in man measured by intravenous infusion of L-[U-14C]lysine. , 1967, Clinical science.

[251]  F. Mahoney,et al.  FUNCTIONAL EVALUATION: THE BARTHEL INDEX. , 2018, Maryland state medical journal.

[252]  S. Katz,et al.  STUDIES OF ILLNESS IN THE AGED. THE INDEX OF ADL: A STANDARDIZED MEASURE OF BIOLOGICAL AND PSYCHOSOCIAL FUNCTION. , 1963, JAMA.

[253]  S. Katz.  Studies of illness in the aged , 1963 .

[254]  B. Caballero,et al.  PROTEINS and amino acids. , 1945, American professional pharmacist.