PTC-bearing mRNA elicits a genetic compensation response via Upf3a and COMPASS components

[1]  A. Jose.  The analysis of living systems can generate both knowledge and illusions , 2020, eLife.

[2]  I. Vetter,et al.  Animal toxins — Nature’s evolutionary-refined toolkit for basic research and drug discovery , 2020, Biochemical Pharmacology.

[3]  Yong Zhu,et al.  Impaired oocyte maturation and ovulation in membrane progestin receptor (mPR) knockouts in zebrafish , 2020, Molecular and Cellular Endocrinology.

[4]  Hao Jiang.  The complex activities of the SET1/MLL complex core subunits in development and disease. , 2020, Biochimica et biophysica acta. Gene regulatory mechanisms.

[5]  M. Gonçalves,et al.  Adenoviral Vectors Meet Gene Editing: A Rising Partnership for the Genomic Engineering of Human Stem Cells and Their Progeny , 2020, Cells.

[6]  Wei Zhang,et al.  Short body length phenotype is compensated by the upregulation of nidogen family members in a deleterious nid1a mutation of zebrafish. , 2017, Journal of genetics and genomics = Yi chuan xue bao.

[7]  Aviv Regev,et al.  RNA targeting with CRISPR–Cas13 , 2017, Nature.

[8]  A. Shilatifard,et al.  Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification. , 2017, Molecular cell.

[9]  K. Peterson,et al.  The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay , 2016, Cell.

[10]  Annika Schuermann,et al.  Metallothionein 2 regulates endothelial cell migration through transcriptional regulation of vegfc expression , 2015, Angiogenesis.

[11]  D. Stainier,et al.  Genetic compensation induced by deleterious mutations but not gene knockdowns , 2015, Nature.

[12]  M. Estelle,et al.  Auxin binding protein 1 (ABP1) is not required for either auxin signaling or Arabidopsis development , 2015, Proceedings of the National Academy of Sciences.

[13]  Nan Li,et al.  Two independent transcription initiation codes overlap on vertebrate core promoters , 2014, Nature.

[14]  L. Zon,et al.  A Network of Epigenetic Regulators Guide Developmental Hematopoiesis In Vivo , 2013, Nature Cell Biology.

[15]  J. Tena,et al.  The developmental epigenomics toolbox: ChIP-seq and MethylCap-seq profiling of early zebrafish embryos. , 2013, Methods.

[16]  Alexander S. Garruss,et al.  The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells , 2013, Nature Structural &Molecular Biology.

[17]  Howard Y. Chang,et al.  The NeST Long ncRNA Controls Microbial Susceptibility and Epigenetic Activation of the Interferon-γ Locus , 2013, Cell.

[18]  D. Lane,et al.  Def defines a conserved nucleolar pathway that leads p53 to proteasome-independent degradation , 2013, Cell Research.

[19]  A. Shilatifard.  The COMPASS family of histone H3K4 methylases: mechanisms of regulation in development and disease pathogenesis. , 2012, Annual review of biochemistry.

[20]  Jinrong Peng,et al.  liver-enriched gene 1a and 1b Encode Novel Secretory Proteins Essential for Normal Liver Development in Zebrafish , 2011, PloS one.

[21]  Howard Y. Chang,et al.  A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression , 2011, Nature.

[22]  Aviv Regev,et al.  Chromatin signature of embryonic pluripotency is established during genome activation , 2010, Nature.

[23]  Madelaine Gogol,et al.  Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II , 2009, Molecular and Cellular Biology.

[24]  J. Gécz,et al.  A UPF3-mediated regulatory switch that maintains RNA surveillance , 2009, Nature Structural &Molecular Biology.

[25]  Steffen Schmidt,et al.  Nonsense-Mediated mRNA Decay Effectors Are Essential for Zebrafish Embryonic Development and Survival , 2009, Molecular and Cellular Biology.

[26]  Peng Fei Wang,et al.  Molecular Regulation of H3K4 Trimethylation by Wdr82, a Component of Human Set1/COMPASS , 2008, Molecular and Cellular Biology.

[27]  O. Mühlemann,et al.  Transcriptional Silencing of Nonsense Codon-containing Immunoglobulin μ Genes Requires Translation of Its mRNA* , 2007, Journal of Biological Chemistry.

[28]  Yudong D. He,et al.  Transcriptional and phenotypic comparisons of Ppara knockout and siRNA knockdown mice , 2006, Nucleic acids research.

[29]  M. Hentze,et al.  Functions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translation. , 2006, RNA.

[30]  Zhenhai Zhang,et al.  Loss of function of def selectively up-regulates Delta113p53 expression to arrest expansion growth of digestive organs in zebrafish. , 2005, Genes & development.

[31]  O. Mühlemann,et al.  Transcriptional silencing of nonsense codon-containing immunoglobulin minigenes. , 2005, Molecular cell.

[32]  Z. Oltvai,et al.  Network biology: understanding the cell's functional organization , 2004, Nature Reviews Genetics.

[33]  G. Dreyfuss,et al.  Role of the Nonsense-Mediated Decay Factor hUpf3 in the Splicing-Dependent Exon-Exon Junction Complex , 2001, Science.

[34]  J. Steitz,et al.  Human Upf Proteins Target an mRNA for Nonsense-Mediated Decay When Bound Downstream of a Termination Codon , 2000, Cell.

[35]  S. Lehnart,et al.  Why Do We Still Have a Maternally Inherited Mitochondrial DNA ? Insights from Evolutionary Medicine , 2007 .