Automated Fuzzy-Connectedness-Based Segmentation in Extraction of Multiple Sclerosis Lesions

In the current study, a fuzzy-connectedness-based approach to fine segmentation of demyelination lesions in Multiple Sclerosis is introduced as an enhancement to the existing ‘fast’ segmentation method. First a fuzzy connectedness relation is introduced, next a short overview of the ‘fast’ segmentation method is presented. Finally, a novel, automated segmentation approach is described. The combined method is applied to segmentation of clinical Magnetic Resonance FLAIR Images.

[1]  Supun Samarasekera,et al.  Multiple sclerosis lesion quantification using fuzzy-connectedness principles , 1997, IEEE Transactions on Medical Imaging.

[2]  Benoit M. Dawant,et al.  Morphometric analysis of white matter lesions in MR images: method and validation , 1994, IEEE Trans. Medical Imaging.

[3]  E. Pietka,et al.  Kernelized Fuzzy c-means Method in Fast Segmentation of Demyelination Plaques in Multiple Sclerosis , 2007, 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[4]  Ioannis A. Kakadiaris,et al.  Image segmentation based on fuzzy connectedness using dynamic weights , 2006, IEEE Transactions on Image Processing.

[5]  B.R. Sajja,et al.  A unified approach for lesion segmentation on MRI of multiple sclerosis , 2004, The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[6]  Bruno Alfano,et al.  Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis , 2000 .

[7]  R. Kikinis,et al.  Quantitative follow‐up of patients with multiple sclerosis using MRI: Technical aspects , 1999, Journal of magnetic resonance imaging : JMRI.

[8]  L. R. Dice Measures of the Amount of Ecologic Association Between Species , 1945 .

[9]  Supun Samarasekera,et al.  Fuzzy Connectedness and Object Definition: Theory, Algorithms, and Applications in Image Segmentation , 1996, CVGIP Graph. Model. Image Process..

[10]  James C. Bezdek,et al.  Pattern Recognition with Fuzzy Objective Function Algorithms , 1981, Advanced Applications in Pattern Recognition.