Hiperparatiroidismo primario. Experiencia inicial con cirugía de mínima invasión

Summary The most common cause of primary hyperparathyroidism is an adenoma. The sole cure for this disease is correct localization and extirpation of this benign neoplasm. The traditional surgical approach for primary hyperparathyroidism involved a large cervical incision and extensive dissection to identify the four parathyroid glands, localizing and resecting the adenoma. This procedure was time-consuming and had a significant potential for morbidity. With the introduction of modern diagnostic procedures, it is now possible to obtain pre-operative localization of the adenoma and to use minimally invasive techniques to resect it with the aid of a radioguided gamma probe. The procedure can be done in outpatient units with minimal discomfort to patients.

[1]  C. Russell Unilateral neck exploration for primary hyperparathyroidism. , 2004, The Surgical clinics of North America.

[2]  Rafael García Ortiz,et al.  Resección de adenoma paratiroideo ectópico retroesternal con técnica de invasión mínima radio-guiada. Informe de un caso , 2001 .

[3]  J. Monchik,et al.  Minimally invasive parathyroid surgery. , 2000, The Surgical clinics of North America.

[4]  L. Sokoll,et al.  One Hundred Consecutive Minimally Invasive Parathyroid Explorations , 2000, Annals of surgery.

[5]  A. Piotto,et al.  99mTc-MIBI Radioguided Surgery for Limited Invasive Parathyroidectomy , 2000, Tumori.

[6]  W. Martin,et al.  Effect of minimally invasive radioguided parathyroidectomy on efficacy, length of stay, and costs in the management of primary hyperparathyroidism. , 2000, Annals of surgery.

[7]  P. C. Smit,et al.  Direct, minimally invasive adenomectomy for primary hyperparathyroidism: An alternative to conventional neck exploration? , 2000, Annals of surgery.

[8]  A. G. Vicente,et al.  Cirugía paratiroidea mínimamente invasiva con gammagrafía con 99mTc-sestamibi y cirugía radioguiada con sonda: resultados preliminares , 2000 .

[9]  A. G. García Vicente,et al.  [Minimally invasive parathyroid surgery with 99mTc-sestamibi scintigraphy and probe-radioguided surgery: preliminary results]. , 2000, Revista Española de Medicina Nuclear.

[10]  Y. Nagatani,et al.  Hyperfunctional parathyroid glands with 99mTc-MIBI scan: semiquantitative analysis correlated with histologic findings. , 1999, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[11]  J. Thompson,et al.  Sentinel lymph node detection and imaging. , 1999, European journal of nuclear medicine.

[12]  S. Teplick,et al.  General case of the day. Ectopic retrosternal parathyroid adenoma. , 1999, Radiographics : a review publication of the Radiological Society of North America, Inc.

[13]  P. Ell,et al.  Sentinel lymph node detection and imaging , 1999, European Journal of Nuclear Medicine.

[14]  L. Holmberg,et al.  Population based case-control study of sick leave in postmenopausal women before diagnosis of hyperparathyroidism , 1998, BMJ.

[15]  M. Nathan,et al.  The ectopic parathyroid adenoma: a cost justification for routine preoperative localization with technetium Tc 99m sestamibi scan. , 1998, Archives of otolaryngology--head & neck surgery.

[16]  C. Farrell,et al.  Minimally invasive parathyroidectomy for primary hyperparathyroidism: decreasing operative time and potential complications while improving cosmetic results. , 1998, The American surgeon.

[17]  A. V. Dalen,et al.  Successful minimally invasive surgery in primary hyperparathyroidism after combined preoperative ultrasound and computed tomography imaging , 1998 .

[18]  J. Norman,et al.  Cost-effectiveness of preoperative sestamibi scan for primary hyperparathyroidism is dependent solely upon the surgeon's choice of operative procedure. , 1998, Journal of the American College of Surgeons.

[19]  M. Ishibashi,et al.  Comparison of technetium-99m-MIBI, technetium-99m-tetrofosmin, ultrasound and MRI for localization of abnormal parathyroid glands. , 1998, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[20]  C. C. Elvir,et al.  Adenoma paratiroideo en la infancia , 1998 .

[21]  L. Voltolini,et al.  Ectopic parathyroid adenoma. Two cases treated with video-assisted thoracoscopic surgery. , 1998, Scandinavian cardiovascular journal : SCJ.

[22]  E. Hindié,et al.  Primary hyperparathyroidism: higher success rate of first surgery after preoperative Tc-99m sestamibi-I-123 subtraction scanning. , 1997, Radiology.

[23]  J. Rodríguez,et al.  Efficacy of preoperative diagnostic imaging localization of technetium 99m-sestamibi scintigraphy in hyperparathyroidism. , 1997, Surgery.

[24]  W. O'Fallon,et al.  The Rise and Fall of Primary Hyperparathyroidism: A Population-Based Study in Rochester, Minnesota, 1965-1992 , 1997, Annals of Internal Medicine.

[25]  S. Silverberg,et al.  Evaluation and management of primary hyperparathyroidism. , 1996, The Journal of clinical endocrinology and metabolism.

[26]  C. Oh Surgical treatment of primary hyperparathyroidism. , 1995 .

[27]  A. F. Stewart,et al.  Primary hyperparathyroidism: preoperative localization using technetium-sestamibi scanning. , 1995, The Journal of clinical endocrinology and metabolism.

[28]  S. Chandarlapaty,et al.  A New Approach to Parathyroidectomy , 1994, Annals of surgery.

[29]  A. Graeff,et al.  Ectopic parathyroid adenoma in the posterior triangle of the neck. , 1993, Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion.

[30]  R. Taillefer,et al.  Detection and localization of parathyroid adenomas in patients with hyperparathyroidism using a single radionuclide imaging procedure with technetium-99m-sestamibi (double-phase study) , 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[31]  R E Collins,et al.  Parathyroid imaging with technetium-99m-sestamibi: preoperative localization and tissue uptake studies. , 1992, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

[32]  C. Grant,et al.  Surgical treatment of primary hyperparathyroidism: An institutional perspective , 1991, World journal of surgery.

[33]  M. Brennan,et al.  NIH conference. Diagnosis and management of asymptomatic primary hyperparathyroidism: consensus development conference statement. , 1991, Annals of internal medicine.

[34]  C. A. Hardin,et al.  Surgical treatment of primary hyperparathyroidism. , 1977, American journal of surgery.