论文信息 - Enzyme semiconductor sensor based on butyrylcholinesterase

Enzyme semiconductor sensor based on butyrylcholinesterase

Abstract An enzyme field-effect transistor with a gelatin membrane containing butyrylcholinesterase (BCE) is investigated. The membrane formation procedure and experimental conditions are optimized. The sensor exhibits sensitivity to butyrylcholine in the range 10−4−10−2 mol/l with a response time 2 min. The influence of reversible and irreversible inhibitors on the sensor characteristics is studied.

[1] Isao Karube,et al. Acetylcholine Sensor Based on Ion Sensitive Field Effect Transistor and Acetylcholine Receptor , 1987 .

[2] Tadayuki Matsuo,et al. Penicillin sensors based on an ion-sensitive field effect transistor coated with stearic acid Langmuir-Blodgett membrane. , 1988 .

[3] Kunihiro Ichimura,et al. Integrated enzyme fets for simultaneous detections of urea and glucose , 1985 .

[4] Louis H. Goodson,et al. An immobilized cholinesterase product for use in the rapid detection of enzyme inhibitors in air or water. , 1973, Analytical biochemistry.

[5] P. Bergveld,et al. ISFET based enzyme sensors. , 1987, Biosensors.