Bibliometric study of the toxicology of nanoescale zero valent iron used in soil remediation.

The application of nanoscale zero-valent iron is one of the most widely used remediation technologies; however, the potential environmental risks of this technology are largely unknown. In order to broaden the knowledge on this subject, the present work consists of a bibliometric study of all of publications related to the toxicity of zero-valent iron nanoparticles used in soil remediation available from the Scopus (Elsevier) and Web of Science (Thompson Reuters) databases. This study presents a temporal distribution of the publications, the most cited articles, the authors who have made the greatest contribution to the theme, and the institutions, countries, and scientific journals that have published the most on this subject. The use of bibliometrics has allowed for the visualization of a panorama of the publications, providing an appropriate analysis to guide new research towards an effective contribution to science by filling the existing gaps. In particular, the lack of studies in several countries reveals a promising area for the development of further research on this topic.

[1]  Yen-Ping Peng,et al.  Nano zerovalent iron particles induce pulmonary and cardiovascular toxicity in an in vitro human co-culture model , 2016, Nanotoxicology.

[2]  Yong Sik Ok,et al.  Review on nano zerovalent iron (nZVI): From synthesis to environmental applications , 2016 .

[3]  Sedigheh Mehrabian,et al.  Antimicrobial and Genotoxicity Effects of Zero-valent Iron Nanoparticles , 2014, Jundishapur journal of microbiology.

[4]  Amitava Mukherjee,et al.  Toxicity, accumulation, and trophic transfer of chemically and biologically synthesized nano zero valent iron in a two species freshwater food chain. , 2017, Aquatic toxicology.

[5]  Eakalak Khan,et al.  Membrane Alterations in Pseudomonas putida F1 Exposed to Nanoscale Zerovalent Iron: Effects of Short-Term and Repetitive nZVI Exposure. , 2017, Environmental science & technology.

[6]  Yingying Xie,et al.  Remediation and phytotoxicity of decabromodiphenyl ether contaminated soil by zero valent iron nanoparticles immobilized in mesoporous silica microspheres. , 2016, Journal of environmental management.

[7]  Mark R Wiesner,et al.  Effect of a fullerene water suspension on bacterial phospholipids and membrane phase behavior. , 2007, Environmental science & technology.

[8]  V. H. Liao,et al.  Nanoscale zerovalent iron (nZVI) at environmentally relevant concentrations induced multigenerational reproductive toxicity in Caenorhabditis elegans. , 2016, Chemosphere.

[9]  Thomas Birk,et al.  Review of the Evidence from Epidemiology, Toxicology, and Lung Bioavailability on the Carcinogenicity of Inhaled Iron Oxide Particulates. , 2016, Chemical research in toxicology.

[10]  R. Sethi,et al.  Nanoscale zerovalent iron particles for groundwater remediation: a review , 2014 .

[11]  Roberto Rosal,et al.  A Colloidal Singularity Reveals the Crucial Role of Colloidal Stability for Nanomaterials In-Vitro Toxicity Testing: nZVI-Microalgae Colloidal System as a Case Study , 2014, PloS one.

[12]  K. Ünlü,et al.  A Laboratory Column Investigation for the Treatment of Cr(VI) with Zero-Valent Iron , 2009 .

[13]  Han-Qing Yu,et al.  Impact of zero-valent iron nanoparticles on the activity of anaerobic granular sludge: From macroscopic to microcosmic investigation. , 2017, Water research.

[14]  T. Cajthaml,et al.  Ecotoxicity and environmental safety related to nano-scale zerovalent iron remediation applications , 2016, Applied Microbiology and Biotechnology.

[15]  Cheng Lei,et al.  Toxicity of iron-based nanoparticles to green algae: Effects of particle size, crystal phase, oxidation state and environmental aging. , 2016, Environmental pollution.

[16]  Akon Higuchi,et al.  Iron and iron oxide nanoparticles are highly toxic to Culex quinquefasciatus with little non-target effects on larvivorous fishes , 2018, Environmental Science and Pollution Research.

[17]  Mansour Ghorbanpour,et al.  Mitigating effect of nano-zerovalent iron, iron sulfate and EDTA against oxidative stress induced by chromium in Helianthus annuus L. , 2018, Acta Physiologiae Plantarum.

[18]  Cristina Delerue-Matos,et al.  Ecotoxicological impact of two soil remediation treatments in Lactuca sativa seeds. , 2016, Chemosphere.

[19]  Irene M C Lo,et al.  Magnetic nanoparticles: essential factors for sustainable environmental applications. , 2013, Water research.

[20]  Eakalak Khan,et al.  Impact of nanoscale zero valent iron on bacteria is growth phase dependent. , 2016, Chemosphere.

[21]  Miroslav Mashlan,et al.  Multimodal action and selective toxicity of zerovalent iron nanoparticles against cyanobacteria. , 2012, Environmental science & technology.

[22]  Donald Lucas,et al.  Oxidative stress induced by zero-valent iron nanoparticles and Fe(II) in human bronchial epithelial cells. , 2009, Environmental science & technology.

[23]  Feng Zhao,et al.  The dual effects of carboxymethyl cellulose on the colloidal stability and toxicity of nanoscale zero-valent iron. , 2016, Chemosphere.

[24]  Zhiqiang Hu,et al.  Impact of metallic and metal oxide nanoparticles on wastewater treatment and anaerobic digestion. , 2013, Environmental science. Processes & impacts.

[25]  Amitava Mukherjee,et al.  Toxicity assessment of zero valent iron nanoparticles on Artemia salina , 2017, Environmental toxicology.

[26]  Oxana V. Kharissova,et al.  Iron-containing nanomaterials: synthesis, properties, and environmental applications , 2012 .

[27]  K. Wu,et al.  The zerovalent iron nanoparticle causes higher developmental toxicity than its oxidation products in early life stages of medaka fish. , 2013, Water research.

[28]  Helge Stanjek,et al.  The ecotoxic potential of a new zero-valent iron nanomaterial, designed for the elimination of halogenated pollutants, and its effect on reductive dechlorinating microbial communities. , 2016, Environmental pollution.

[29]  Yang Deng,et al.  Phytotoxicity and uptake of nanoscale zero-valent iron (nZVI) by two plant species. , 2013, The Science of the total environment.

[30]  Masarin Ban,et al.  Effect of submicron and nano-iron oxide particles on pulmonary immunity in mice. , 2012, Toxicology letters.

[31]  M. Černík,et al.  Oxidative stress in microorganisms exposed to iron nanoparticles , 2010 .

[32]  Mark R Wiesner,et al.  Antibacterial activity of fullerene water suspensions (nC60) is not due to ROS-mediated damage. , 2008, Nano letters.

[33]  Wei Zhang,et al.  The biochemical and toxicological responses of earthworm (Eisenia fetida) following exposure to nanoscale zerovalent iron in a soil system , 2016, Environmental Science and Pollution Research.

[34]  Ravi Naidu,et al.  Environmental application and ecological significance of nano-zero valent iron. , 2016, Journal of environmental sciences.

[35]  Zhen Wang,et al.  Global trends in sediment-related research in earth science during 1992–2011: a bibliometric analysis , 2013, Scientometrics.

[36]  M. C. Lobo,et al.  Assessing the impact of zero-valent iron (ZVI) nanotechnology on soil microbial structure and functionality: a molecular approach. , 2012, Chemosphere.

[37]  M. Gil-Díaz,et al.  Residual impact of aged nZVI on heavy metal-polluted soils. , 2015, The Science of the total environment.

[38]  E. Joner,et al.  Ecotoxicological effects on earthworms of fresh and aged nano-sized zero-valent iron (nZVI) in soil. , 2012, Chemosphere.

[39]  Krishna R. Reddy.  Evolution of geoenvironmental engineering , 2014 .

[40]  Kuen-Song Lin,et al.  Antimicrobial effects of zero-valent iron nanoparticles on gram-positive Bacillus strains and gram-negative Escherichia coli strains , 2017, Journal of Nanobiotechnology.

[41]  C. Fajardo,et al.  Integrating classical and molecular approaches to evaluate the impact of nanosized zero-valent iron (nZVI) on soil organisms. , 2014, Chemosphere.

[42]  Yongyou Hu,et al.  Bacterial effects and interfacial inactivation mechanism of nZVI/Pd on Pseudomonas putida strain. , 2017, Water research.

[43]  Cheng Lei,et al.  Environmental transformations and ecological effects of iron-based nanoparticles. , 2018, Environmental pollution.

[44]  Zeqin Li,et al.  Distribution and mobility of metals in agricultural soils near a copper smelter in South China , 2006, Environmental geochemistry and health.

[45]  Eakalak Khan,et al.  Role of oxidative stress in inactivation of Escherichia coli BW25113 by nanoscale zero-valent iron. , 2016, The Science of the total environment.

[46]  Boon Leong Lim,et al.  Environmental Risks of Nano Zerovalent Iron for Arsenate Remediation: Impacts on Cytosolic Levels of Inorganic Phosphate and MgATP2- in Arabidopsis thaliana. , 2018, Environmental science & technology.

[47]  Pei-Jen Chen,et al.  Toxicity assessments of nanoscale zerovalent iron and its oxidation products in medaka (Oryzias latipes) fish. , 2011, Marine pollution bulletin.

[48]  Antônio Thomé,et al.  Review of Nanotechnology for Soil and Groundwater Remediation: Brazilian Perspectives , 2015, Water, Air, & Soil Pollution.

[49]  Arturo A. Keller,et al.  Toxicity of Nano-Zero Valent Iron to Freshwater and Marine Organisms , 2012, PloS one.

[50]  Jan Němeček,et al.  Nanoscale zero-valent iron application for in situ reduction of hexavalent chromium and its effects on indigenous microorganism populations. , 2014, The Science of the total environment.

[51]  Khara D Grieger,et al.  Environmental benefits and risks of zero-valent iron nanoparticles (nZVI) for in situ remediation: risk mitigation or trade-off? , 2010, Journal of contaminant hydrology.

[52]  Awadhesh N Jha,et al.  Stabilization of engineered zero-valent nanoiron with Na-acrylic copolymer enhances spermiotoxicity. , 2011, Environmental science & technology.

[53]  S. Ghosh,et al.  Green fluorescent protein-expressing Escherichia coli as a model system for investigating the antimicrobial activities of silver nanoparticles. , 2006, Langmuir : the ACS journal of surfaces and colloids.

[54]  Julian Bosch,et al.  Biological effects of four iron-containing nanoremediation materials on the green alga Chlamydomonas sp. , 2018, Ecotoxicology and environmental safety.

[55]  Mark R Wiesner,et al.  A review of the environmental implications of in situ remediation by nanoscale zero valent iron (nZVI): Behavior, transport and impacts on microbial communities. , 2016, The Science of the total environment.

[56]  G. Janer,et al.  Acute ecotoxicity of coated colloidal goethite nanoparticles on Daphnia magna: Evaluating the influence of exposure approaches. , 2017, The Science of the total environment.

[57]  Pedro J J Alvarez,et al.  Effect of natural organic matter on toxicity and reactivity of nano-scale zero-valent iron. , 2011, Water research.

[58]  G Libralato,et al.  Ecofriendly nanotechnologies and nanomaterials for environmental applications: Key issue and consensus recommendations for sustainable and ecosafe nanoremediation. , 2018, Ecotoxicology and environmental safety.

[59]  Geoffrey R Mitchell,et al.  Nanoscale zerovalent iron alters soil bacterial community structure and inhibits chloroaromatic biodegradation potential in Aroclor 1242-contaminated soil. , 2013, Environmental pollution.

[60]  Wei-xian Zhang,et al.  Iron nanoparticles for environmental clean-up: recent developments and future outlook. , 2013, Environmental science. Processes & impacts.

[61]  T. Xia,et al.  Understanding biophysicochemical interactions at the nano-bio interface. , 2009, Nature materials.

[62]  G Libralato,et al.  Phytotoxicity of ionic, micro- and nano-sized iron in three plant species. , 2016, Ecotoxicology and environmental safety.

[63]  Hongwei Rong,et al.  Utilization of nanomaterials for in-situ remediation of heavy metal(loid) contaminated sediments: A review. , 2019, The Science of the total environment.

[64]  Richard D Handy,et al.  Are reproduction impairments of free spawning marine invertebrates exposed to zero-valent nano-iron associated with dissolution of nanoparticles? , 2013, Nanotoxicology.

[65]  Mallavarapu Megharaj,et al.  Inhibition or promotion of biodegradation of nitrate by Paracoccus sp. in the presence of nanoscale zero-valent iron. , 2015, The Science of the total environment.

[66]  Milica Velimirovic,et al.  Use of CAH-degrading bacteria as test-organisms for evaluating the impact of fine zerovalent iron particles on the anaerobic subsurface environment. , 2015, Chemosphere.

[67]  Ian P Thompson,et al.  Tactic response of bacteria to zero-valent iron nanoparticles. , 2016, Environmental pollution.

[68]  Chung-Min Liao,et al.  In situ remediation-released zero-valent iron nanoparticles impair soil ecosystems health: A C. elegans biomarker-based risk assessment. , 2016, Journal of hazardous materials.

[69]  E. Joner,et al.  Impact of Fe and Ag nanoparticles on seed germination and differences in bioavailability during exposure in aqueous suspension and soil , 2012, Environmental toxicology.

[70]  Stacey M. Louie,et al.  Research highlights: improved understanding of ecological impacts resulting from nanomaterial-based in situ remediation , 2016 .

[71]  Bernd Nowack,et al.  Are engineered nano iron oxide particles safe? an environmental risk assessment by probabilistic exposure, effects and risk modeling , 2016, Nanotoxicology.

[72]  Khara D Grieger,et al.  Conceptual modeling for identification of worst case conditions in environmental risk assessment of nanomaterials using nZVI and C60 as case studies. , 2011, The Science of the total environment.

[73]  Leen Bastiaens,et al.  Inhibition of sulfate reducing bacteria in aquifer sediment by iron nanoparticles. , 2014, Water research.

[74]  Guibin Jiang,et al.  Effects of waterborne nano-iron on medaka (Oryzias latipes): antioxidant enzymatic activity, lipid peroxidation and histopathology. , 2009, Ecotoxicology and environmental safety.

[75]  Wei Zhang,et al.  The reproductive responses of earthworms (Eisenia fetida) exposed to nanoscale zero-valent iron (nZVI) in the presence of decabromodiphenyl ether (BDE209). , 2017, Environmental pollution.

[76]  D. White,et al.  The effect of engineered iron nanoparticles on growth and metabolic status of marine microalgae cultures. , 2012, The Science of the total environment.

[77]  Guangming Zeng,et al.  Nanoscale zero-valent iron assisted phytoremediation of Pb in sediment: Impacts on metal accumulation and antioxidative system of Lolium perenne. , 2018, Ecotoxicology and environmental safety.

[78]  C. Fajardo,et al.  Molecular Stress Responses to Nano-Sized Zero-Valent Iron (nZVI) Particles in the Soil Bacterium Pseudomonas stutzeri , 2014, PloS one.

[79]  Tanapon Phenrat,et al.  Partial oxidation ("aging") and surface modification decrease the toxicity of nanosized zerovalent iron. , 2009, Environmental science & technology.

[80]  Yoon-Seok Chang,et al.  Nano/bio treatment of polychlorinated biphenyls with evaluation of comparative toxicity. , 2015, Journal of hazardous materials.

[81]  Amitava Mukherjee,et al.  In planta genotoxicity of nZVI: influence of colloidal stability on uptake, DNA damage, oxidative stress and cell death , 2017, Mutagenesis.

[82]  Kairong Lin,et al.  Chemical stability and toxicity of nanoscale zero-valent iron in the remediation of chromium-contaminated watershed , 2013 .

[83]  Ecaterina Matei,et al.  Nano-Iron Oxides Used for Environmental Applications , 2013 .

[84]  Daniel W. Elliott,et al.  Zero-Valent Iron Nanoparticles for Abatement of Environmental Pollutants: Materials and Engineering Aspects , 2006 .

[85]  C. Fajardo,et al.  Transcriptional and proteomic stress responses of a soil bacterium Bacillus cereus to nanosized zero-valent iron (nZVI) particles. , 2013, Chemosphere.

[86]  C. Fajardo,et al.  Three Functional Biomarkers for Monitoring the Nanoscale Zero-Valent Iron (nZVI)-Induced Molecular Signature on Soil Organisms , 2016, Water, Air, & Soil Pollution.

[87]  R. Sumitha,et al.  Standardization of Alternative Methods for Nanogenotoxicity Testing in Drosophila melanogaster Using Iron Nanoparticles: A Promising Link to Nanodosimetry , 2016 .

[88]  Yoshiyuki Takeda,et al.  Nanobiotechnology as an emerging research domain from nanotechnology: A bibliometric approach , 2009, Scientometrics.

[89]  Rune Hjorth,et al.  Ecotoxicity testing and environmental risk assessment of iron nanomaterials for sub-surface remediation - Recommendations from the FP7 project NanoRem. , 2017, Chemosphere.

[90]  Dongye Zhao,et al.  Ageing decreases the phytotoxicity of zero-valent iron nanoparticles in soil cultivated with Oryza sativa , 2016, Ecotoxicology.

[91]  Jae-hwan Kim,et al.  Carboxymethyl cellulose coating decreases toxicity and oxidizing capacity of nanoscale zerovalent iron. , 2014, Chemosphere.

[92]  Kelvin B. Gregory,et al.  Impact of nanoscale zero valent iron on geochemistry and microbial populations in trichloroethylene contaminated aquifer materials. , 2010, Environmental science & technology.

[93]  Pedro J J Alvarez,et al.  Adsorbed polymer and NOM limits adhesion and toxicity of nano scale zerovalent iron to E. coli. , 2010, Environmental science & technology.

[94]  E. Joner,et al.  Effects of nano-sized zero-valent iron (nZVI) on DDT degradation in soil and its toxicity to collembola and ostracods. , 2013, Chemosphere.

[95]  Sujit Bhattacharya,et al.  China and India: The two new players in the nanotechnology race , 2012, Scientometrics.

[96]  Hung-Yee Shu,et al.  Enhancement of microbial reductive dechlorination of polychlorinated biphenyls (PCBs) in a marine sediment by nanoscale zerovalent iron (NZVI) particles , 2012 .

[97]  M. Černík,et al.  DDT degradation efficiency and ecotoxicological effects of two types of nano-sized zero-valent iron (nZVI) in water and soil. , 2016, Chemosphere.

[98]  Arturo A. Keller,et al.  Emerging patterns for engineered nanomaterials in the environment: a review of fate and toxicity studies , 2014, Journal of Nanoparticle Research.

[99]  Pedro J J Alvarez,et al.  Effects of nano-scale zero-valent iron particles on a mixed culture dechlorinating trichloroethylene. , 2010, Bioresource technology.

[100]  Alok Sinha,et al.  A review on synthesis, characterization, and applications of nano zero valent iron (nZVI) for environmental remediation , 2016 .

[101]  D. Oughton,et al.  Effects of nano-sized zero-valent iron on DDT degradation and residual toxicity in soil: a column experiment , 2013, Plant and Soil.

[102]  Karl Ritz,et al.  The impact of zero-valent iron nanoparticles upon soil microbial communities is context dependent , 2013, Environmental Science and Pollution Research.

[103]  Pei-Jen Chen,et al.  Stabilization or oxidation of nanoscale zerovalent iron at environmentally relevant exposure changes bioavailability and toxicity in medaka fish. , 2012, Environmental science & technology.