Ebola virus disease: A narrative review.

[1]  A. Garbuglia,et al.  Diagnostics of Ebola virus , 2023, Frontiers in Public Health.

[2]  Zheng Wang,et al.  Development and Clinical Evaluation of a Rapid Point of Care Test for Ebola Virus Infection in Humans , 2023, Viruses.

[3]  S. Goodman,et al.  Bombali Ebolavirus in Mops condylurus Bats (Molossidae), Mozambique , 2022, Emerging infectious diseases.

[4]  T. Kanneganti,et al.  Filoviruses: Innate Immunity, Inflammatory Cell Death, and Cytokines , 2022, Pathogens.

[5]  G. Kobinger,et al.  Ebola Virus Encodes Two microRNAs in Huh7-Infected Cells , 2022, International journal of molecular sciences.

[6]  A. Binagwaho,et al.  Infectious disease outbreaks highlight gender inequity , 2022, Nature Microbiology.

[7]  A. Rizvanov,et al.  Structural and Functional Aspects of Ebola Virus Proteins , 2021, Pathogens.

[8]  E. Ohimain,et al.  The 2013-2016 Ebola virus disease outbreak in West Africa. , 2021, Current opinion in pharmacology.

[9]  J. Quick,et al.  Resurgence of Ebola virus in 2021 in Guinea suggests a new paradigm for outbreaks , 2021, Nature.

[10]  D. Aschenbrenner.  Monoclonal Antibody Approved to Treat Ebola. , 2021, The American Journal of Nursing.

[11]  P. Maes,et al.  Human Diversity of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen Class I Alleles and Ebola Virus Disease Outcomes , 2021, Emerging infectious diseases.

[12]  R. Kennedy,et al.  The role of host genetics in the immune response to SARS‐CoV‐2 and COVID‐19 susceptibility and severity , 2020, Immunological reviews.

[13]  Donald S. Grant,et al.  Ebola-Specific CD8+ and CD4+ T Cell Responses in Sierra Leonean Ebola Virus Survivors with and without Post Viral Sequelae. , 2020, The Journal of infectious diseases.

[14]  L. Mboera,et al.  Forty-two years of responding to Ebola virus outbreaks in Sub-Saharan Africa: a review , 2020, BMJ Global Health.

[15]  J. Kuhn,et al.  Ebola virus disease , 2020, Nature Reviews Disease Primers.

[16]  Walter A Alarcon,et al.  Ebola Virus Disease Outbreak — Democratic Republic of the Congo, August 2018–November 2019 , 2019, MMWR. Morbidity and mortality weekly report.

[17]  J. Anaya,et al.  Ebola virus disease: An emerging and re-emerging viral threat. , 2019, Journal of autoimmunity.

[18]  Michael Proschan,et al.  A Randomized, Controlled Trial of Ebola Virus Disease Therapeutics. , 2019, The New England journal of medicine.

[19]  Justine R. Smith,et al.  Expression of microRNA in human retinal pigment epithelial cells following infection with Zaire ebolavirus , 2019, BMC Research Notes.

[20]  M. Katze,et al.  Ebola virus-mediated T-lymphocyte depletion is the result of an abortive infection , 2019, PLoS pathogens.

[21]  M. Boiro,et al.  Bombali Virus in Mops condylurus Bats, Guinea , 2019, Emerging infectious diseases.

[22]  M. Masika,et al.  Bombali Virus in Mops condylurus Bat, Kenya , 2019, Emerging infectious diseases.

[23]  G. Ippolito,et al.  Inflammatory and Humoral Immune Response during Ebola Virus Infection in Survivor and Fatal Cases Occurred in Sierra Leone during the 2014–2016 Outbreak in West Africa , 2019, Viruses.

[24]  J. Mascola,et al.  Safety, tolerability, pharmacokinetics, and immunogenicity of the therapeutic monoclonal antibody mAb114 targeting Ebola virus glycoprotein (VRC 608): an open-label phase 1 study , 2019, The Lancet.

[25]  S. Günther,et al.  Ebola virus disease , 2019, The Lancet.

[26]  M. Schreiber,et al.  Maximizing the Resilience of Healthcare Workers in Multi-hazard Events: Lessons from the 2014-2015 Ebola Response in Africa. , 2019, Military medicine.

[27]  M. Mateo,et al.  Immune parameters and outcomes during Ebola virus disease. , 2019, JCI insight.

[28]  D. Westreich,et al.  Stigma and Ebola survivorship in Liberia: Results from a longitudinal cohort study , 2018, PloS one.

[29]  A. Fauci,et al.  The Extended Impact of Human Immunodeficiency Virus/AIDS Research , 2018, The Journal of infectious diseases.

[30]  E. Rubin,et al.  The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses , 2018, Nature Microbiology.

[31]  S. Sivapalasingam,et al.  Safety, pharmacokinetics, and immunogenicity of a co-formulated cocktail of three human monoclonal antibodies targeting Ebola virus glycoprotein in healthy adults: a randomised, first-in-human phase 1 study. , 2018, The Lancet. Infectious diseases.

[32]  G. Gao,et al.  Serological Investigation of Laboratory-Confirmed and Suspected Ebola Virus Disease Patients During the Late Phase of the Ebola Outbreak in Sierra Leone , 2018, Virologica Sinica.

[33]  Y. Sakurai,et al.  Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates , 2018, The Journal of infectious diseases.

[34]  J. Qian,et al.  A Rapid Screen for Host-Encoded miRNAs with Inhibitory Effects against Ebola Virus Using a Transcription- and Replication-Competent Virus-Like Particle System , 2018, International journal of molecular sciences.

[35]  M. Martcheva,et al.  Efficacy of control measures in the control of Ebola, Liberia 2014–2015 , 2018, Journal of biological dynamics.

[36]  G. Guyatt,et al.  Evidence-based guidelines for supportive care of patients with Ebola virus disease , 2017, The Lancet.

[37]  P. Formenty,et al.  Ebola RNA Persistence in Semen of Ebola Virus Disease Survivors — Final Report , 2017, The New England journal of medicine.

[38]  A. Levine,et al.  Characteristics and survival of patients with Ebola virus infection, malaria, or both in Sierra Leone: a retrospective cohort study. , 2017, The Lancet. Infectious diseases.

[39]  Desmond E. Williams,et al.  Ebola Virus RNA in Semen from an HIV-Positive Survivor of Ebola , 2017, Emerging infectious diseases.

[40]  F. Kashanchi,et al.  The Role of Exosomal VP40 in Ebola Virus Disease. , 2017, DNA and cell biology.

[41]  D. Medaglini,et al.  Immunomonitoring of human responses to the rVSV-ZEBOV Ebola vaccine. , 2017, Current opinion in virology.

[42]  T. Oduyebo,et al.  Ebola virus disease and pregnancy: A review of the current knowledge of Ebola virus pathogenesis, maternal, and neonatal outcomes , 2017, Birth Defects Research.

[43]  William B. Klimstra,et al.  MicroRNA Regulation of RNA Virus Replication and Pathogenesis , 2016, Trends in Molecular Medicine.

[44]  I. Messaoudi,et al.  Molecular mechanisms of Ebola pathogenesis , 2016, Journal of leukocyte biology.

[45]  D. Bausch,et al.  Ebola Virus Shedding and Transmission: Review of Current Evidence. , 2016, The Journal of infectious diseases.

[46]  Robert J. Fischer,et al.  Plasmodium Parasitemia Associated With Increased Survival in Ebola Virus-Infected Patients. , 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[47]  D. Mead,et al.  Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly From Blood. , 2016, The Journal of infectious diseases.

[48]  P. Formenty,et al.  Analysis of Diagnostic Findings From the European Mobile Laboratory in Guéckédou, Guinea, March 2014 Through March 2015 , 2016, The Journal of infectious diseases.

[49]  S. Günther,et al.  Evaluation of RealStar Reverse Transcription–Polymerase Chain Reaction Kits for Filovirus Detection in the Laboratory and Field , 2016, The Journal of infectious diseases.

[50]  Ian Goodfellow,et al.  Resurgence of Ebola Virus Disease in Guinea Linked to a Survivor With Virus Persistence in Seminal Fluid for More Than 500 Days , 2016, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[51]  O. Azeez-Akande.  Emergence of ebola virus disease and its devastating impact in poor-resourced areas of sub-Saharan Africa , 2016 .

[52]  M. J. Broadhurst,et al.  Diagnosis of Ebola Virus Disease: Past, Present, and Future , 2016, Clinical Microbiology Reviews.

[53]  B. Bell,et al.  Overview, Control Strategies, and Lessons Learned in the CDC Response to the 2014-2016 Ebola Epidemic. , 2016, MMWR supplements.

[54]  D. Bausch,et al.  Sequelae of Ebola virus disease: the emergency within the emergency. , 2016, The Lancet. Infectious diseases.

[55]  G. Gao,et al.  Ebola virus encodes a miR-155 analog to regulate importin-α5 expression , 2016, Cellular and Molecular Life Sciences.

[56]  H. Schuitemaker,et al.  Safety and Immunogenicity of Novel Adenovirus Type 26- and Modified Vaccinia Ankara-Vectored Ebola Vaccines: A Randomized Clinical Trial. , 2016, JAMA.

[57]  S. Bavari,et al.  BCX4430 – A broad-spectrum antiviral adenosine nucleoside analog under development for the treatment of Ebola virus disease , 2016, Journal of Infection and Public Health.

[58]  J. Mascola,et al.  Protective monotherapy against lethal Ebola virus infection by a potently neutralizing antibody , 2016, Science.

[59]  G. Gao,et al.  Two-mAb cocktail protects macaques against the Makona variant of Ebola virus , 2016, Science Translational Medicine.

[60]  M. J. Broadhurst,et al.  Performance of the GeneXpert Ebola Assay for Diagnosis of Ebola Virus Disease in Sierra Leone: A Field Evaluation Study , 2016, PLoS medicine.

[61]  Ruifu Yang,et al.  Pluripotency-associated miR-290/302 family of microRNAs promote the dismantling of naive pluripotency , 2016, Cell Research.

[62]  A. Takada,et al.  Development and Evaluation of Reverse Transcription-Loop-Mediated Isothermal Amplification (RT-LAMP) Assay Coupled with a Portable Device for Rapid Diagnosis of Ebola Virus Disease in Guinea , 2016, PLoS neglected tropical diseases.

[63]  R. Van den Bergh,et al.  Feasibility of Xpert Ebola Assay in Médecins Sans Frontières Ebola Program, Guinea , 2016, Emerging infectious diseases.

[64]  G. Gao,et al.  Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1 , 2016, Cell.

[65]  Jens H Kuhn,et al.  Molecular Evidence of Sexual Transmission of Ebola Virus. , 2015, The New England journal of medicine.

[66]  J. Pawęska,et al.  Comparative Evaluation of the Diagnostic Performance of the Prototype Cepheid GeneXpert Ebola Assay , 2015, Journal of Clinical Microbiology.

[67]  J. Dye,et al.  Novel Small Molecule Entry Inhibitors of Ebola Virus. , 2015, The Journal of infectious diseases.

[68]  S. Sridhar.  Clinical development of Ebola vaccines , 2015, Therapeutic advances in vaccines.

[69]  M. J. Broadhurst,et al.  ReEBOV Antigen Rapid Test kit for point-of-care and laboratory-based testing for Ebola virus disease: a field validation study , 2015, The Lancet.

[70]  Ajeet Kaushik,et al.  Towards detection and diagnosis of Ebola virus disease at point-of-care , 2015, Biosensors and Bioelectronics.

[71]  C. Agrati,et al.  Molecular mechanisms of Ebola virus pathogenesis: focus on cell death , 2015, Cell Death and Differentiation.

[72]  K. Dhama,et al.  Ebola from emergence to epidemic: the virus and the disease, global preparedness and perspectives. , 2015, Journal of infection in developing countries.

[73]  S. Rewar,et al.  Transmission of ebola virus disease: an overview. , 2015, Annals of global health.

[74]  B. Löwe,et al.  Ebola and Psychological Stress of Health Care Professionals , 2015, Emerging infectious diseases.

[75]  P. Shears,et al.  Ebola virus disease in Africa: epidemiology and nosocomial transmission. , 2015, The Journal of hospital infection.

[76]  T. Vogl,et al.  Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care , 2015, The Lancet.

[77]  I. Messaoudi,et al.  Pathophysiology of Ebola Virus Infection: Current Challenges and Future Hopes. , 2015, ACS infectious diseases.

[78]  Jay B. Varkey,et al.  Human Ebola virus infection results in substantial immune activation , 2015, Proceedings of the National Academy of Sciences.

[79]  A. Sher,et al.  Type I interferons in infectious disease , 2015, Nature Reviews Immunology.

[80]  J. Audet,et al.  Immune evasion in ebolavirus infections. , 2015, Viral immunology.

[81]  Pardis C Sabeti,et al.  GB Virus C Coinfections in West African Ebola Patients , 2014, Journal of Virology.

[82]  A. Ansari.  Clinical features and pathobiology of Ebolavirus infection. , 2014, Journal of autoimmunity.

[83]  W. Edmunds,et al.  Potential for large outbreaks of Ebola virus disease , 2014, Epidemics.

[84]  Christopher Dye,et al.  Ebola virus disease in the Democratic Republic of Congo. , 2014, The New England journal of medicine.

[85]  G. Chowell,et al.  Transmission dynamics and control of Ebola virus disease (EVD): a review , 2014, BMC Medicine.

[86]  Hongwei Liang,et al.  Identification of Ebola virus microRNAs and their putative pathological function , 2014, Science China Life Sciences.

[87]  David A. Mead,et al.  A novel thermostable polymerase for RNA and DNA loop-mediated isothermal amplification (LAMP) , 2014, Front. Microbiol..

[88]  Gianluca Pegoraro,et al.  Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430 , 2014, Nature.

[89]  Y H Li,et al.  Evolutionary history of Ebola virus , 2013, Epidemiology and Infection.

[90]  P. Rollin,et al.  Genomic analysis of filoviruses associated with four viral hemorrhagic fever outbreaks in Uganda and the Democratic Republic of the Congo in 2012. , 2013, Virology.

[91]  T. Hope,et al.  Cellular Factors Implicated in Filovirus Entry , 2013, Advances in virology.

[92]  Stuart T. Nichol,et al.  Reemerging Sudan Ebola Virus Disease in Uganda, 2011 , 2012, Emerging infectious diseases.

[93]  J. Wood,et al.  Ebola Virus Antibodies in Fruit Bats, Ghana, West Africa , 2012, Emerging infectious diseases.

[94]  J. Yasuda.  Ebolavirus Replication and Tetherin/BST-2 , 2012, Front. Microbio..

[95]  J. Stapleton,et al.  GB virus C: the good boy virus? , 2012, Trends in microbiology.

[96]  Philip J. L. Gould,et al.  Filovirus outbreak detection and surveillance: lessons from Bundibugyo. , 2011, The Journal of infectious diseases.

[97]  Jens H. Kuhn,et al.  Proposal for a revised taxonomy of the family Filoviridae: classification, names of taxa and viruses, and virus abbreviations , 2010, Archives of Virology.

[98]  B. Prabhakar,et al.  The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide. , 2010, The Journal of general virology.

[99]  Steven B. Bradfute,et al.  Mechanisms and Consequences of Ebolavirus-Induced Lymphocyte Apoptosis , 2009, The Journal of Immunology.

[100]  David F. Smith,et al.  A Novel Mechanism for LSECtin Binding to Ebola Virus Surface Glycoprotein through Truncated Glycans* , 2008, Journal of Biological Chemistry.

[101]  N. Sullivan,et al.  Immunopathology of highly virulent pathogens: insights from Ebola virus , 2007, Nature Immunology.

[102]  B. Berkhout,et al.  The Ebola Virus VP35 Protein Is a Suppressor of RNA Silencing , 2007, PLoS pathogens.

[103]  Peter D. Walsh,et al.  Ebola Outbreak Killed 5000 Gorillas , 2006, Science.

[104]  J. Gonzalez,et al.  Fruit bats as reservoirs of Ebola virus , 2005, Nature.

[105]  Ghislain Moussavou,et al.  The natural history of Ebola virus in Africa. , 2005, Microbes and infection.

[106]  W. Karesh,et al.  Wild Animal Mortality Monitoring and Human Ebola Outbreaks, Gabon and Republic of Congo, 2001–2003 , 2005, Emerging infectious diseases.

[107]  P. Formenty,et al.  Multiple Ebola Virus Transmission Events and Rapid Decline of Central African Wildlife , 2004, Science.

[108]  P. Jahrling,et al.  Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection. , 2003, The American journal of pathology.

[109]  M. Bray,et al.  Ebola hemorrhagic fever and septic shock. , 2003, The Journal of infectious diseases.

[110]  H. Klenk,et al.  The Ebola Virus VP35 Protein Inhibits Activation of Interferon Regulatory Factor 3 , 2003, Journal of Virology.

[111]  B. Pulendran,et al.  Cutting Edge: Impairment of Dendritic Cells and Adaptive Immunity by Ebola and Lassa Viruses1 , 2003, The Journal of Immunology.

[112]  F. Omaswa,et al.  An outbreak of Ebola in Uganda , 2002, Tropical medicine & international health : TM & IH.

[113]  Emiko Suzuki,et al.  Ebola Virus VP40 Drives the Formation of Virus-Like Filamentous Particles Along with GP , 2002, Journal of Virology.

[114]  M. Bray.  The role of the Type I interferon response in the resistance of mice to filovirus infection. , 2001, The Journal of general virology.

[115]  A. Sanchez,et al.  Recombinant RNA replicons derived from attenuated Venezuelan equine encephalitis virus protect guinea pigs and mice from Ebola hemorrhagic fever virus. , 2000, Vaccine.

[116]  A. K. Hansen,et al.  Marburg and Ebola virus infections in laboratory non-human primates: a literature review. , 2000, Comparative medicine.

[117]  J. McCormick,et al.  Diagnosis of Ebola haemorrhagic fever by RT‐PCR in an epidemic setting , 2000, Journal of medical virology.

[118]  P. Debré,et al.  Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients , 1999, Nature Medicine.

[119]  A. Sanchez,et al.  The reemergence of Ebola hemorrhagic fever, Democratic Republic of the Congo, 1995. Commission de Lutte contre les Epidémies à Kikwit. , 1999, The Journal of infectious diseases.

[120]  P. Jahrling,et al.  ELISA for the detection of antibodies to Ebola viruses. , 1999, The Journal of infectious diseases.

[121]  M. Georges-Courbot,et al.  Ebola hemorrhagic fever outbreaks in Gabon, 1994-1997: epidemiologic and health control issues. , 1999, The Journal of infectious diseases.

[122]  C. Boesch,et al.  Ebola virus outbreak among wild chimpanzees living in a rain forest of Côte d'Ivoire. , 1999, The Journal of infectious diseases.

[123]  A. Sanchez,et al.  Persistence and genetic stability of Ebola virus during the outbreak in Kikwit, Democratic Republic of the Congo, 1995. , 1999, The Journal of infectious diseases.

[124]  R. Colebunders,et al.  Ebola outbreak in Kikwit, Democratic Republic of the Congo: discovery and control measures. , 1999, The Journal of infectious diseases.

[125]  P. Jahrling,et al.  Evaluation of immune globulin and recombinant interferon-alpha2b for treatment of experimental Ebola virus infections. , 1999, The Journal of infectious diseases.

[126]  P. Jahrling,et al.  Pathology of experimental Ebola virus infection in African green monkeys. Involvement of fibroblastic reticular cells. , 1997, Archives of pathology & laboratory medicine.

[127]  C. Boesch,et al.  Isolation and partial characterisation of a new strain of Ebola virus , 1995, The Lancet.

[128]  A. Chepurnov,et al.  [The effect of some physical and chemical factors on inactivation of the Ebola virus]. , 1995, Voprosy virusologii.

[129]  G. Neild,et al.  Ultrastructural pathology of experimental ebola haemorrhagic fever virus infection , 1985, Journal of Pathology.

[130]  D. Heymann,et al.  Ebola hemorrhagic fever: Tandala, Zaire, 1977-1978. , 1980, The Journal of infectious diseases.

[131]  T. H. Maugh.  A malaria primer. , 1977, Science.

[132]  Tom Fletcher,et al.  Clinical presentation of patients with Ebola virus disease in Conakry, Guinea. , 2015, The New England journal of medicine.

[133]  K. Laupland,et al.  Ebola virus disease , 2014, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale.

[134]  Heinz Feldmann,et al.  Disease modeling for Ebola and Marburg viruses , 2009, Disease Models & Mechanisms.

[135]  B. Hewlett,et al.  [Outbreak of Ebola hemorrhagic fever in the Republic of the Congo, 2003: a new strategy?]. , 2003, Medecine tropicale : revue du Corps de sante colonial.

[136]  J. McCormick,et al.  Ebola virus disease in southern Sudan: hospital dissemination and intrafamilial spread. , 1983, Bulletin of the World Health Organization.

[137]  Ebola haemorrhagic fever in Sudan, 1976. Report of a WHO/International Study Team. , 1978, Bulletin of the World Health Organization.

[138]  Ebola haemorrhagic fever in Zaire, 1976. , 1978, Bulletin of the World Health Organization.

[139]  E. Leroy,et al.  L es épidémies de fièvre hémorragique due au virus Ebola au Gabon ( 1994-2002 ) : , 2022 .