Cryptic MLL-AF10 fusion caused by insertion of duplicated 5' part of MLL into 10p12 in acute leukemia: a case report.

[1]  N. Douet-Guilbert,et al.  Cryptic 5' MLL gene insertion in an X-chromosome in acute myeloblastic leukemia. , 2005, Cancer genetics and cytogenetics.

[2]  C. Bloomfield,et al.  Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies. , 2004, Blood.

[3]  W. Hiddemann,et al.  Cytogenetics, fluorescence in situ hybridization, and reverse transcriptase polymerase chain reaction are necessary to clarify the various mechanisms leading to an MLL-AF10 fusion in acute myelocytic leukemia with 10;11 rearrangement. , 2003, Cancer genetics and cytogenetics.

[4]  S. Korsmeyer,et al.  The role of MLL in hematopoiesis and leukemia , 2002, Current opinion in hematology.

[5]  M. König,et al.  A highly specific and sensitive fluorescence in situ hybridization assay for the detection of t(4;11)(q21;q23) and concurrent submicroscopic deletions in acute leukaemias , 2002, British journal of haematology.

[6]  F. Speleman,et al.  Molecular cytogenetic analysis of 10;11 rearrangements in acute myeloid leukemia , 2002, Leukemia.

[7]  M. Cleary,et al.  Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins , 2001, Oncogene.

[8]  M. Höglund,et al.  Paired multiplex reverse-transcriptase polymerase chain reaction (PMRT-PCR) analysis as a rapid and accurate diagnostic tool for the detection of MLL fusion genes in hematologic malignancies , 2001, Leukemia.

[9]  J. Squire,et al.  Primary chromosomal rearrangements of leukemia are frequently accompanied by extensive submicroscopic deletions and may lead to altered prognosis. , 2001, Blood.

[10]  C. Croce,et al.  Sequence analysis of the breakpoint cluster region in the ALL-1 gene involved in acute leukemia. , 1994, Cancer research.