An expeditious synthesis of tamoxifen, a representative SERM (selective estrogen receptor modulator), via the three-component coupling reaction among aromatic aldehyde, cinnamyltrimethylsilane, and beta-chlorophenetole.
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M. Ikekita | Y. Nagahara | Akane Sasaki | Isamu Shiina | K. Nakata | Y. Sano | Masahiko Suzuki | Tomomi Miyamoto | Toshikazu Yokoyama | Tomoko Orikasa | Yoshimune Hasome