HLA class II antibodies induce necrotic cell death in human endothelial cells via a lysosomal membrane permeabilization-mediated pathway

[1]  W. Land,et al.  Origin and Consequences of Necroinflammation. , 2018, Physiological reviews.

[2]  E. Reed,et al.  HLA Class II–Triggered Signaling Cascades Cause Endothelial Cell Proliferation and Migration: Relevance to Antibody-Mediated Transplant Rejection , 2018, The Journal of Immunology.

[3]  Dimitri Krainc,et al.  Mitochondria-lysosome contacts regulate mitochondrial fission via Rab7 GTP hydrolysis , 2018, Nature.

[4]  B. Stockwell,et al.  Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease , 2017, Cell.

[5]  E. Reed,et al.  Antibody-mediated rejection across solid organ transplants: manifestations, mechanisms, and therapies , 2017, The Journal of clinical investigation.

[6]  A. Linkermann,et al.  The in vivo evidence for regulated necrosis , 2017, Immunological reviews.

[7]  X. Jouven,et al.  Value of Donor-Specific Anti-HLA Antibody Monitoring and Characterization for Risk Stratification of Kidney Allograft Loss. , 2017, Journal of the American Society of Nephrology : JASN.

[8]  P. Agostinis,et al.  Transplantation and Damage‐Associated Molecular Patterns (DAMPs) , 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[9]  P. Agostinis,et al.  DAMP—Induced Allograft and Tumor Rejection: The Circle Is Closing , 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[10]  D. Richardson,et al.  A mechanism for overcoming P-glycoprotein-mediated drug resistance: novel combination therapy that releases stored doxorubicin from lysosomes via lysosomal permeabilization using Dp44mT or DpC , 2016, Cell Death & Disease.

[11]  P. Boya,et al.  Lysosomal membrane permeabilization in cell death: new evidence and implications for health and disease , 2016, Annals of the New York Academy of Sciences.

[12]  M. Carmagnat,et al.  HLA Class II Antibody Activation of Endothelial Cells Promotes Th17 and Disrupts Regulatory T Lymphocyte Expansion , 2016, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[13]  Hao Jiang,et al.  SAR650984 directly induces multiple myeloma cell death via lysosomal-associated and apoptotic pathways, which is further enhanced by pomalidomide , 2016, Leukemia.

[14]  P. Vandenabeele,et al.  Regulated necrosis: disease relevance and therapeutic opportunities , 2016, Nature Reviews Drug Discovery.

[15]  R. Blasczyk,et al.  Heme Oxygenase-1 Inhibits HLA Class I Antibody-Dependent Endothelial Cell Activation , 2015, PloS one.

[16]  P. Nickerson,et al.  Rates and Determinants of Progression to Graft Failure in Kidney Allograft Recipients With De Novo Donor‐Specific Antibody , 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[17]  S. Jimenez,et al.  Increased Expression of NAPDH Oxidase 4 in Systemic Sclerosis Dermal Fibroblasts: Regulation by Transforming Growth Factor β , 2015, Arthritis & rheumatology.

[18]  I. Gromova,et al.  Sensitive detection of lysosomal membrane permeabilization by lysosomal galectin puncta assay , 2015, Autophagy.

[19]  A. Nègre-Salvayre,et al.  Role of Sphingosine‐1‐Phosphate in Transplant Vasculopathy Evoked by Anti‐HLA Antibody , 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[20]  Deborah A. Flusberg,et al.  Surviving apoptosis: life-death signaling in single cells. , 2015, Trends in cell biology.

[21]  Liping Jiang,et al.  Citreoviridin Induces Autophagy-Dependent Apoptosis through Lysosomal-Mitochondrial Axis in Human Liver HepG2 Cells , 2015, Toxins.

[22]  E. Reed,et al.  Monocyte Recruitment by HLA IgG‐Activated Endothelium: The Relationship Between IgG Subclass and FcγRIIa Polymorphisms , 2015, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[23]  F. Baltazar,et al.  Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria , 2015, Cell Death and Disease.

[24]  Lorenzo Galluzzi,et al.  Metabolic control of cell death , 2014, Science.

[25]  R. Blasczyk,et al.  Semaphorin 3A alters endothelial cell immunogenicity by regulating Class II transactivator activity circuits , 2014, Transfusion.

[26]  P. Vandenabeele,et al.  Regulated necrosis: the expanding network of non-apoptotic cell death pathways , 2014, Nature Reviews Molecular Cell Biology.

[27]  D. Longo,et al.  Necroptosis. , 2014, The New England journal of medicine.

[28]  Andy H. Choi,et al.  Current Perspectives , 2013, Journal of dental research.

[29]  Christer S. Ejsing,et al.  Transformation-associated changes in sphingolipid metabolism sensitize cells to lysosomal cell death induced by inhibitors of acid sphingomyelinase. , 2013, Cancer cell.

[30]  Fatmah M A Naemi,et al.  Anti-Donor HLA Class I Antibodies: Pathways to Endothelial Cell Activation and Cell-Mediated Allograft Rejection , 2013, Transplantation.

[31]  E. Reed,et al.  HLA Class I Antibodies Trigger Increased Adherence of Monocytes to Endothelial Cells by Eliciting an Increase in Endothelial P-Selectin and, Depending on Subclass, by Engaging FcγRs , 2013, The Journal of Immunology.

[32]  J. Papadimitriou,et al.  Endothelial injury in renal antibody-mediated allograft rejection: a schematic view based on pathogenesis. , 2013, Transplantation.

[33]  M. Jäättelä,et al.  Lysosomal cell death at a glance , 2013, Journal of Cell Science.

[34]  J. Vita,et al.  Mitochondria and Endothelial Function , 2013, Circulation research.

[35]  S. Immenschuh,et al.  Antibodies against dengue virus nonstructural protein-1 induce heme oxygenase-1 via a redox-dependent pathway in human endothelial cells. , 2013, Free radical biology & medicine.

[36]  M. Stegall,et al.  The role of complement in antibody-mediated rejection in kidney transplantation , 2012, Nature Reviews Nephrology.

[37]  Mary E. Ziegler,et al.  HLA class I-mediated stress fiber formation requires ERK1/2 activation in the absence of an increase in intracellular Ca2+ in human aortic endothelial cells. , 2012, American journal of physiology. Cell physiology.

[38]  R. Knight,et al.  Necroptosis , 2012, JAK-STAT.

[39]  H. Pelicano,et al.  Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway. , 2012, Blood.

[40]  R. Colvin,et al.  A Novel Pathway of Chronic Allograft Rejection Mediated by NK Cells and Alloantibody , 2012, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[41]  Kathryn J Wood,et al.  Mechanisms of rejection: current perspectives. , 2012, Transplantation.

[42]  D. Glotz,et al.  Immunological function of the endothelial cell within the setting of organ transplantation. , 2011, Immunology letters.

[43]  C. Wiethoff,et al.  Adenovirus Type 5 Rupture of Lysosomes Leads to Cathepsin B-Dependent Mitochondrial Stress and Production of Reactive Oxygen Species , 2011, Journal of Virology.

[44]  N. Banner,et al.  De Novo Donor HLA‐Specific Antibodies after Heart Transplantation Are an Independent Predictor of Poor Patient Survival , 2011, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[45]  S. Alexander,et al.  Rejection of the kidney allograft. , 2010, The New England journal of medicine.

[46]  A. Zylicz,et al.  Hsp70 stabilizes lysosomes and reverts Niemann–Pick disease-associated lysosomal pathology , 2010, Nature.

[47]  E. Reed,et al.  Effect of Antibodies on Endothelium , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[48]  T. Illidge,et al.  Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells. , 2009, The Journal of clinical investigation.

[49]  Michael P. Murphy,et al.  How mitochondria produce reactive oxygen species , 2008, The Biochemical journal.

[50]  S. Tullius,et al.  Impact of innate and adaptive immunity on rejection and tolerance. , 2008, Transplantation.

[51]  F. Gao,et al.  Anti-MHC Class I Antibody Activation of Proliferation and Survival Signaling in Murine Cardiac Allografts1 , 2008, The Journal of Immunology.

[52]  W. Baldwin,et al.  Antibody and complement in transplant vasculopathy. , 2007, Circulation research.

[53]  R. Colvin,et al.  Antibody-mediated organ-allograft rejection , 2005, Nature Reviews Immunology.

[54]  N. Voelkel,et al.  Initial apoptosis is followed by increased proliferation of apoptosis‐resistant endothelial cells , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[55]  J. Soulillou,et al.  Vascular Endothelial Cells Evade Apoptosis Triggered by Human Leukocyte Antigen-DR Ligation Mediated by Allospecific Antibodies , 2004, Transplantation.

[56]  H. Khalil,et al.  Delineation of the HLA-DR Region and the Residues Involved in the Association with the Cytoskeleton* , 2004, Journal of Biological Chemistry.

[57]  W. Baldwin,et al.  Non‐Complement‐ and Complement‐Activating Antibodies Synergize to Cause Rejection of Cardiac Allografts , 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[58]  E. Bröcker,et al.  MHC class II-mediated apoptosis in dendritic cells: a role for membrane-associated and mitochondrial signaling pathways. , 2003, International immunology.

[59]  J. Byrd,et al.  Mitochondria control of cell death induced by anti-HLA-DR antibodies , 2003, Leukemia.

[60]  G. Kroemer,et al.  Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion , 2003, The Journal of experimental medicine.

[61]  D. Charron,et al.  Signaling through HLA‐DR induces PKCβ‐dependent B cell death outside rafts , 2003 .

[62]  D. Charron,et al.  Signaling through HLA-DR induces PKC beta-dependent B cell death outside rafts. , 2003, European journal of immunology.

[63]  Yee‐Shin Lin,et al.  Endothelial Cell Apoptosis Induced by Antibodies Against Dengue Virus Nonstructural Protein 1 Via Production of Nitric Oxide1 , 2002, The Journal of Immunology.

[64]  F. Deist,et al.  HLA class II-mediated death is induced via Fas/Fas ligand interactions in human splenic B lymphocytes. , 1997, Blood.

[65]  D. Pinson,et al.  Regulation by transforming growth factor-beta 1 of expression and function of the receptor for IFN-gamma on mouse macrophages. , 1992, Journal of immunology.

[66]  [The circle is closing]. , 1966, Sairaanhoitaja. Sjukskoterskan.