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Stereochemical mechanism of action for thymidylate synthase based on the X-ray structure of the covalent inhibitory ternary complex with 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate.
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D. Matthews
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S. Freer
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C. Janson
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J. E. Villafranca
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W. W. Smith
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K. Welsh
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