Human adipose tissue binds and metabolizes the endocannabinoids anandamide and 2-arachidonoylglycerol.
暂无分享,去创建一个
F. Fezza | M. Maccarrone | N. Battista | V. Gasperi | G. Parlongo | B. Spoto | E. Sgrò | C. Zoccali | M. Maccarrone | Carmine Zoccali
[1] F. Fezza,et al. New insights into endocannabinoid degradation and its therapeutic potential. , 2006, Mini reviews in medicinal chemistry.
[2] D. Cota,et al. The emerging role of the endocannabinoid system in endocrine regulation and energy balance. , 2006, Endocrine reviews.
[3] B. Scatton,et al. The Canadian Consortium for the Investigation of Cannabinoids in Human Therapeutics , 2022 .
[4] M. Maccarrone. Fatty acid amide hydrolase: a potential target for next generation therapeutics. , 2006, Current pharmaceutical design.
[5] M. Gonthier,et al. Presence of the cannabinoid receptors, CB1 and CB2, in human omental and subcutaneous adipocytes , 2006, Histochemistry and Cell Biology.
[6] M. Cascio,et al. Endocannabinoid metabolic pathways and enzymes. , 2005, Current drug targets. CNS and neurological disorders.
[7] K. Mackie,et al. Identification functional characterization of brainstem cannabinoid CB2 receptors. , 2022 .
[8] B. Barboni,et al. Characterization of the endocannabinoid system in boar spermatozoa and implications for sperm capacitation and acrosome reaction , 2005, Journal of Cell Science.
[9] Arya M. Sharma,et al. Activation of the peripheral endocannabinoid system in human obesity. , 2005, Diabetes.
[10] P. Casellas,et al. Anandamide induced PPARgamma transcriptional activation and 3T3-L1 preadipocyte differentiation. , 2005, European journal of pharmacology.
[11] A. Gerber,et al. Overweight and obesity associated with a missense polymorphism in fatty acid amide hydrolase (FAAH) , 2005, International Journal of Obesity.
[12] B. Cravatt,et al. Structure and function of fatty acid amide hydrolase. , 2005, Annual review of biochemistry.
[13] M. Maj,et al. Blood Levels of the Endocannabinoid Anandamide are Increased in Anorexia Nervosa and in Binge-Eating Disorder, but not in Bulimia Nervosa , 2005, Neuropsychopharmacology.
[14] K. Mackie,et al. Endocannabinoid activation at hepatic CB1 receptors stimulates fatty acid synthesis and contributes to diet-induced obesity. , 2005, The Journal of clinical investigation.
[15] V. Marzo,et al. Endocannabinoid control of food intake and energy balance , 2005, Nature Neuroscience.
[16] A. Rissanen,et al. Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study , 2005, The Lancet.
[17] M. Kosteljanetz,et al. Endocannabinoid metabolism in human glioblastomas and meningiomas compared to human non‐tumour brain tissue , 2005, Journal of neurochemistry.
[18] F. Fezza,et al. Radiochromatographic assay of N-acyl-phosphatidylethanolamine-specific phospholipase D activity. , 2005, Analytical biochemistry.
[19] M. Stock,et al. Effects of the cannabinoid CB1 receptor antagonist SR141716 on oxygen consumption and soleus muscle glucose uptake in Lepob/Lepob mice , 2005, International Journal of Obesity.
[20] J. Herbert,et al. The anti‐obesity effect of rimonabant is associated with an improved serum lipid profile , 2005, Diabetes, obesity & metabolism.
[21] M. Korbonits,et al. The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin , 2004, British journal of pharmacology.
[22] V. Large,et al. Metabolism of lipids in human white adipocyte. , 2004, Diabetes & metabolism.
[23] V. Marzo,et al. Endovanilloids. Putative endogenous ligands of transient receptor potential vanilloid 1 channels. , 2004 .
[24] F. Fezza,et al. Endocannabinoids and their involvement in the neurovascular system. , 2004, Current neurovascular research.
[25] N. Ueda,et al. Molecular Characterization of a Phospholipase D Generating Anandamide and Its Congeners* , 2004, Journal of Biological Chemistry.
[26] Gareth Williams,et al. Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain , 2003, The Journal of cell biology.
[27] C. Hillard,et al. Cellular accumulation of anandamide: consensus and controversy , 2003, British journal of pharmacology.
[28] C. Newton,et al. The cannabinoid system and immune modulation , 2003, Journal of leukocyte biology.
[29] M. Guzmán,et al. Cannabinoids: potential anticancer agents , 2003, Nature Reviews Cancer.
[30] M. Maccarrone,et al. The endocannabinoid system, anandamide and the regulation of mammalian cell apoptosis , 2003, Cell Death and Differentiation.
[31] N. Stella,et al. Arachidonylcyclopropylamide increases microglial cell migration through cannabinoid CB2 and abnormal-cannabidiol-sensitive receptors. , 2003, European journal of pharmacology.
[32] T. Horvath. Endocannabinoids and the regulation of body fat: the smoke is clearing. , 2003, The Journal of clinical investigation.
[33] C. Flachskamm,et al. The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. , 2003, The Journal of clinical investigation.
[34] A. Finazzi-Agro’,et al. Leptin Activates the Anandamide Hydrolase Promoter in Human T Lymphocytes through STAT3* , 2003, The Journal of Biological Chemistry.
[35] Brian Vastag,et al. Experimental drugs take aim at obesity. , 2003, JAMA.
[36] P. Soubrié,et al. The cannabinoid CB1 receptor antagonist SR141716 increases Acrp30 mRNA expression in adipose tissue of obese fa/fa rats and in cultured adipocyte cells. , 2003, Molecular pharmacology.
[37] A. Howlett. The cannabinoid receptors. , 2002, Prostaglandins & other lipid mediators.
[38] E. Berry,et al. Tetrahydrocannabinol and endocannabinoids in feeding and appetite. , 2002, Pharmacology & therapeutics.
[39] T. Freund,et al. Brain monoglyceride lipase participating in endocannabinoid inactivation , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[40] M. Yamakuchi,et al. Simultaneous measurement of anandamide and 2-arachidonoylglycerol by polymyxin B-selective adsorption and subsequent high-performance liquid chromatography analysis: increase in endogenous cannabinoids in the sera of patients with endotoxic shock. , 2001, Analytical biochemistry.
[41] A. Finazzi-Agro’,et al. The Activity of Anandamide at Vanilloid VR1 Receptors Requires Facilitated Transport across the Cell Membrane and Is Limited by Intracellular Metabolism* , 2001, The Journal of Biological Chemistry.
[42] R. Palmiter,et al. Leptin-regulated endocannabinoids are involved in maintaining food intake , 2001, Nature.
[43] V. Di Marzo,et al. Structure‐activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens , 2001, British journal of pharmacology.
[44] S. Dey,et al. Ligand-receptor signaling with endocannabinoids in preimplantation embryo development and implantation. , 2000, Chemistry and physics of lipids.
[45] A. Makriyannis,et al. Functional CB1 cannabinoid receptors in human vascular endothelial cells. , 2000, The Biochemical journal.
[46] Gerald Maguire,et al. Expression of CB2 cannabinoid receptor mRNA in adult rat retina , 2000, Visual Neuroscience.
[47] D. Julius,et al. Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide , 1999, Nature.
[48] P. Blumberg,et al. Vanilloid (Capsaicin) receptors and mechanisms. , 1999, Pharmacological reviews.
[49] J. Shannon,et al. Expression of a brain-type cannabinoid receptor (CB1) in alveolar Type II cells in the lung: regulation by hydrocortisone. , 1997, European journal of pharmacology.
[50] P. C. Schmid,et al. Metabolism of N-acylethanolamine phospholipids by a mammalian phosphodiesterase of the phospholipase D type. , 1983, The Journal of biological chemistry.
[51] R. Mechoulam,et al. The isolation and structure of delta-1-tetrahydrocannabinol and other neutral cannabinoids from hashish. , 1971, Journal of the American Chemical Society.
[52] F. Fezza,et al. The anandamide membrane transporter and the therapeutic implications of its inhibition , 2005 .
[53] R. Pertwee. Pharmacology of cannabinoid CB1 and CB2 receptors. , 1997, Pharmacology & therapeutics.