Diabetes mellitus associated with processed and unprocessed red meat: an overview

Abstract According to American Diabetes Association “as many as 1 in 3 American adults will have diabetes by 2050” imposing a serious burden on healthcare services and highlighting a substantial need to reduce “new-cases” incidence. Diabetes is inextricably linked to diet, in the prevention-spectrum. Red-meat-intake has been positively associated with reduced glycemic control. However, divergence exists among meat subtypes (i.e. fresh and processed) and the magnitude of their impact on diabetes development. The present overview attempted to summarize the latest data regarding red-meat subtypes on the examined association. Four meta-analysis and 10 prospective studies, focusing on the role of fresh and processed red meat in diabetes prevention, were selected. All of studies highlighted the aggravating role of processed meat-products in diabetes incidence, while fresh meat reached significance in only half of them. Therefore, the contribution of fresh red meat on diabetes remains inconclusive. Valid conclusions seem more robust concerning processed-meat-consumption.

[1]  D. Panagiotakos,et al.  Red meat consumption and healthy ageing: A review. , 2016, Maturitas.

[2]  G. Grosso,et al.  A review of recent evidence in human studies of n-3 and n-6 PUFA intake on cardiovascular disease, cancer, and depressive disorders: does the ratio really matter? , 2015, International journal of food sciences and nutrition.

[3]  D. Panagiotakos,et al.  A journey into a Mediterranean diet and type 2 diabetes: a systematic review with meta-analyses , 2015, BMJ Open.

[4]  F. Hu,et al.  Red and processed meat consumption and mortality: dose–response meta-analysis of prospective cohort studies , 2015, Public Health Nutrition.

[5]  P. Clifton,et al.  A review of potential metabolic etiologies of the observed association between red meat consumption and development of type 2 diabetes mellitus. , 2015, Metabolism: clinical and experimental.

[6]  Xingquan Zhao,et al.  The Association between Serum Uric Acid Levels and the Prevalence of Vulnerable Atherosclerotic Carotid Plaque: A Cross-sectional Study , 2015, Scientific Reports.

[7]  T. Norat,et al.  Association between total, processed, red and white meat consumption and all-cause, CVD and IHD mortality: a meta-analysis of cohort studies. , 2014, The British journal of nutrition.

[8]  L. Azadbakht,et al.  Is there a relationship between red or processed meat intake and obesity? A systematic review and meta‐analysis of observational studies , 2014, Obesity reviews : an official journal of the International Association for the Study of Obesity.

[9]  G. Grosso,et al.  Beneficial effects of the Mediterranean diet on metabolic syndrome. , 2014, Current pharmaceutical design.

[10]  J. Trafiałek,et al.  Dietary exposure to meat-related carcinogenic substances: is there a way to estimate the risk? , 2014, International journal of food sciences and nutrition.

[11]  D. Panagiotakos,et al.  The effect of Mediterranean diet on the development of type 2 diabetes mellitus: a meta-analysis of 10 prospective studies and 136,846 participants. , 2014, Metabolism: clinical and experimental.

[12]  S. Larsson,et al.  Systematic Reviews and Meta- and Pooled Analyses Red Meat and Processed Meat Consumption and All-Cause Mortality: A Meta-Analysis , 2014 .

[13]  F. Tinahones,et al.  Inflammation, oxidative stress and metabolic syndrome: dietary modulation. , 2014, Current vascular pharmacology.

[14]  J. Manson,et al.  Changes in red meat consumption and subsequent risk of type 2 diabetes mellitus: three cohorts of US men and women. , 2013, JAMA internal medicine.

[15]  P. Hogan,et al.  Economic Costs of Diabetes in the U , 2013 .

[16]  D. Mozaffarian,et al.  Unprocessed Red and Processed Meats and Risk of Coronary Artery Disease and Type 2 Diabetes – An Updated Review of the Evidence , 2012, Current Atherosclerosis Reports.

[17]  M. Orho-Melander,et al.  High intakes of protein and processed meat associate with increased incidence of type 2 diabetes , 2012, British Journal of Nutrition.

[18]  D. Siscovick,et al.  Associations of processed meat and unprocessed red meat intake with incident diabetes: the Strong Heart Family Study. , 2012, The American journal of clinical nutrition.

[19]  F. Clavel-Chapelon,et al.  Processed and Unprocessed Red Meat Consumption and Incident Type 2 Diabetes Among French Women , 2011, Diabetes Care.

[20]  An Pan,et al.  Red meat consumption and risk of type 2 diabetes: 3 cohorts of US adults and an updated meta-analysis. , 2011, The American journal of clinical nutrition.

[21]  D. Panagiotakos,et al.  The effect of Mediterranean diet on metabolic syndrome and its components: a meta-analysis of 50 studies and 534,906 individuals. , 2011, Journal of the American College of Cardiology.

[22]  L. Kolonel,et al.  Meat consumption and risk of type 2 diabetes: the Multiethnic Cohort , 2010, Public Health Nutrition.

[23]  D. Albanes,et al.  High processed meat consumption is a risk factor of type 2 diabetes in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention study , 2010, British Journal of Nutrition.

[24]  G. Ursin,et al.  Meat consumption and the risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies , 2009, Diabetologia.

[25]  Giuseppe Lippi,et al.  High Serum Uric Acid as a Novel Risk Factor for Type 2 Diabetes , 2008, Diabetes Care.

[26]  M. Entman,et al.  Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction. , 2006, American journal of physiology. Heart and circulatory physiology.

[27]  X. Shu,et al.  The association of meat intake and the risk of type 2 diabetes may be modified by body weight , 2006, International journal of medical sciences.

[28]  N. Clark,et al.  Standards of Medical Care in Diabetes: Response to Power , 2006 .

[29]  A. Krikorian,et al.  Standards of medical care in diabetes--2006. , 2006, Diabetes care.

[30]  D. Mikhailidis,et al.  Awareness, treatment and control of the metabolic syndrome and its components: a multicentre Greek study. , 2005, Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese.

[31]  Walter C Willett,et al.  Dietary patterns, meat intake, and the risk of type 2 diabetes in women. , 2004, Archives of internal medicine.

[32]  J. Manson,et al.  A prospective study of red meat consumption and type 2 diabetes in middle-aged and elderly women: the women's health study. , 2004, Diabetes care.

[33]  Plamen Nikolov,et al.  Economic Costs of Diabetes in the U.S. in 2002 , 2003, Diabetes care.

[34]  D. Alexander.  Red Meat and PRocessed Meat , 2018 .

[35]  Z. Pang,et al.  Red and processed meat consumption and risk of stroke: a meta-analysis of prospective cohort studies , 2013, European Journal of Clinical Nutrition.

[36]  E. Feskens,et al.  Association between dietary meat consumption and incident type 2 diabetes: the EPIC-InterAct study , 2012, Diabetologia.

[37]  A. J. McAfee,et al.  Red meat consumption: an overview of the risks and benefits. , 2010, Meat science.

[38]  D. Giugliano,et al.  Are there specific treatments for the metabolic syndrome? , 2008, The American journal of clinical nutrition.

[39]  D. Panagiotakos,et al.  The relationship between dietary habits, blood glucose and insulin levels among people without cardiovascular disease and type 2 diabetes; the ATTICA study. , 2005, The review of diabetic studies : RDS.

[40]  C. J. McGrath,et al.  Effect of exchange rate return on volatility spill-over across trading regions , 2012 .