Monoisoamyl and mono‐n‐hexyl meso‐2,3‐dimercaptosuccinate in mobilizing 203hg retention in relation to age of rats and route of administration

Monoisoamyl (Mi‐ADMS) and mono‐n‐hexyl (Mn‐HDMS) monoesters of meso‐2,3‐dimercaptosuccinic acid (DMSA) were given orally or parenterally for the mobilization of inorganic mercury in suckling and older rats. Chelators were administered at a dose of 2 × 0.5 mmol kg−1 on two consecutive days 2 weeks after a single 203Hg injection. Six days later, whole‐body, kidney, liver and brain radioactivities were determined in gamma scintillation counters.

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