Stress in Acute Coronary Syndrome: A Cross-Sectional Study in Kelantan and Terengganu, Malaysia

Background: Stress often happens in acute coronary syndrome (ACS) patients, especially during hospitalization. Objectives: The current study intended to identify the prevalence of stress and its associated factors among ACS patients in two selected hospitals in the east coast region of Malaysia. Methods: A total of 400 ACS patients in both hospitals participated in this cross-sectional study. Acute coronary syndrome patients above 18 who can read, speak and understand in Malay and obtained informed consent were included in the study. The study excluded those patients who were intubated, had any altered mental status, were mentally retarded, and had psychological problems. Stress among ACS patients was measured using the validated questionnaire of the Malay version of the Depression Anxiety Stress Scale 21. Logistic regression was used for analysis. Results: Of these ACS patients, 58.5% had stress symptoms. A higher frequency of stress was found in patients of male (63.7%), Malay (82.1%), and married (67.1%). Acute coronary syndrome patients with a history of ischemic heart disease were a strong and independent factor associated with stress (adjusted odds ratio: 1.73, 95% confidence interval: 1.14 - 2.63, P = 0.010). Conclusions: The prevalence of stress in the study population was high and significantly associated with a history of ischemic heart disease. Creating awareness regarding the risk factors of stress is recommended. In addition, policies should be implemented to reduce the risk of stress among patients.

[1]  Andrew Steptoe,et al.  Effects of stress on the development and progression of cardiovascular disease , 2018, Nature Reviews Cardiology.

[2]  P. Prabhu,et al.  Autonomic regulation of systemic inflammation in humans: A multi-center, blinded observational cohort study , 2018, Brain, Behavior, and Immunity.

[3]  M. Fauzi,et al.  Associated Factors of Anxiety among Acute Coronary Syndrome Patients in Kelantan and Terengganu , 2017 .

[4]  R. Lampert,et al.  Mental Stress and Ventricular Arrhythmias , 2016, Current Cardiology Reports.

[5]  S. Girotra,et al.  Acute Coronary Syndrome , 2015, Journal of intensive care medicine.

[6]  K. Davidson,et al.  A test of the diathesis-stress model in the emergency department: who develops PTSD after an acute coronary syndrome? , 2014, Journal of psychiatric research.

[7]  Joel Stein,et al.  Executive summary: heart disease and stroke statistics--2014 update: a report from the American Heart Association. , 2014, Circulation.

[8]  K. Davidson,et al.  The association of emergency department crowding during treatment for acute coronary syndrome with subsequent posttraumatic stress disorder symptoms. , 2013, JAMA Internal Medicine.

[9]  K. Davidson,et al.  Emotional triggers in myocardial infarction: do they matter? , 2013, European heart journal.

[10]  Harlan M Krumholz,et al.  Post-hospital syndrome--an acquired, transient condition of generalized risk. , 2013, The New England journal of medicine.

[11]  Ramli Musa,et al.  Translation, validation and psychometric properties of Bahasa Malaysia version of the Depression Anxiety and Stress Scales (DASS) , 2007 .

[12]  C. Mathers,et al.  Projections of Global Mortality and Burden of Disease from 2002 to 2030 , 2006, PLoS medicine.

[13]  S. Yusuf,et al.  Association of psychosocial risk factors with risk of acute myocardial infarction in 11 119 cases and 13 648 controls from 52 countries (the INTERHEART study): case-control study , 2004, The Lancet.

[14]  Peter Libby,et al.  Current Concepts of the Pathogenesis of the Acute Coronary Syndromes , 2001, Circulation.

[15]  N. Frasure-smith,et al.  In-hospital symptoms of psychological stress as predictors of long-term outcome after acute myocardial infarction in men. , 1991, The American journal of cardiology.

[16]  A. Ibrahim,et al.  Acute myocardial infarction. , 2014, Critical care clinics.

[17]  Mark D. Huffman,et al.  Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association. , 2013, Circulation.