Collapse and restoration of MHC class-I-dependent immune privilege: exploiting the human hair follicle as a model.

[1]  R. Billingham,et al.  Immunologically Privileged Sites in Transplantation Immunology and Oncology , 2015, Perspectives in biology and medicine.

[2]  R. Paus,et al.  The hair follicle and immune privilege. , 2003, The journal of investigative dermatology. Symposium proceedings.

[3]  M. Diaz,et al.  Role for Id‐1 in immunobiology of normal keratinocytes and in basal cell carcinoma , 2003, Experimental dermatology.

[4]  J. M. Lipton,et al.  &agr;-Melanocyte-stimulating hormone protects the allograft in experimental heart transplantation1 , 2002 .

[5]  I. Alican,et al.  Modulation of the peripheral and central inflammatory responses by alpha-melanocyte stimulating hormone. , 2002, Current protein & peptide science.

[6]  F. Momburg,et al.  Tapasin-the keystone of the loading complex optimizing peptide binding by MHC class I molecules in the endoplasmic reticulum. , 2002, Molecular immunology.

[7]  J. Sundberg,et al.  Interleukin-10-deficient mice are less susceptible to the induction of alopecia areata. , 2002, The Journal of investigative dermatology.

[8]  M. Sospedra,et al.  Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus , 2002, European journal of immunology.

[9]  M. Landau,et al.  Mediation of alopecia areata by cooperation between CD4+ and CD8+ T lymphocytes: transfer to human scalp explants on Prkdc(scid) mice. , 2002, Archives of Dermatology.

[10]  W. Jahnen-Dechent,et al.  Differential regulation of the expression of transporters associated with antigen processing, TAP1 and TAP2, by cytokines and lipopolysaccharide in primary human macrophages , 2002, Inflammation Research.

[11]  C. Heldin,et al.  Mechanisms of TGF-beta signaling in regulation of cell growth and differentiation. , 2002, Immunology letters.

[12]  J. Streilein,et al.  Ocular immune privilege and the impact of intraocular inflammation. , 2002, DNA and cell biology.

[13]  S. Cohen,et al.  Current immunosuppression in liver transplantation. , 2002, American journal of therapeutics.

[14]  R. Rizzo,et al.  HLA‐G expression in early embryos is a fundamental prerequisite for the obtainment of pregnancy , 2002, European journal of immunology.

[15]  K. Jarosinski,et al.  Interferon regulatory factor-1 is required for interferon-γ-induced MHC class I genes in astrocytes , 2002, Journal of Neuroimmunology.

[16]  J. Niederkorn,et al.  IMMUNOLOGY AND IMMUNOMODULATION OF CORNEAL TRANSPLANTATION , 2002, International reviews of immunology.

[17]  R. Dummer,et al.  Decreased intraindividual HLA class I expression is due to reduced transcription in advanced melanoma and does not correlate with HLA-G expression. , 2001, The Journal of investigative dermatology.

[18]  J. Krieger,et al.  Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN‐γ‐inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4+ T‐cell activation , 2001, Glia.

[19]  C. Janeway,et al.  How the immune system protects the host from infection. , 2001, Microbes and infection.

[20]  P. Moore,et al.  Interferon-κ, a Novel Type I Interferon Expressed in Human Keratinocytes* , 2001, The Journal of Biological Chemistry.

[21]  A. Christiano,et al.  Hair follicle predetermination. , 2001, Journal of cell science.

[22]  I. Bellinghausen,et al.  The Role of Interleukin 10 in the Regulation of Allergic Immune Responses , 2001, International Archives of Allergy and Immunology.

[23]  A. Erlebacher Why isn't the fetus rejected? , 2001, Current opinion in immunology.

[24]  A. Lenzi,et al.  Control and impairment of immune privilege in the testis and in semen. , 2001, Human reproduction update.

[25]  C. Akdis,et al.  Mechanisms of interleukin‐10‐mediated immune suppression , 2001, Immunology.

[26]  U. Ritz,et al.  The Transporter Associated With Antigen Processing (TAP): Structural Integrity, Expression, Function, and Its Clinical Relevance , 2001, Molecular medicine.

[27]  T. Bieber,et al.  Human epidermal Langerhans' cells are targets for the immunosuppressive macrolide tacrolimus (FK506). , 2001, The Journal of allergy and clinical immunology.

[28]  J. Dausset,et al.  HLA-G truncated isoforms can substitute for HLA-G1 in fetal survival. , 2000, Human immunology.

[29]  E. Fiebiger,et al.  Major histocompatibility complex class II– fetal skin dendritic cells are potent accessory cells of polyclonal T‐cell responses , 2000, Immunology.

[30]  Gina A. Taylor,et al.  Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis , 2000, Cell.

[31]  D. Tobin,et al.  The human hair follicle immune system: cellular composition and immune privilege , 2000, The British journal of dermatology.

[32]  D. Singer,et al.  Transforming Growth Factor-β1 Down-Regulation of Major Histocompatibility Complex Class I in Thyrocytes: Coordinate Regulation Of Two Separate Elements by Thyroid-Specific as Well as Ubiquitous Transcription Factors , 2000 .

[33]  G. Dotto,et al.  Control of murine hair follicle regression (catagen) by TGF‐β1 in vivo , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[34]  R. Paus,et al.  Immunology of the hair follicle: a short journey into terra incognita. , 1999, The journal of investigative dermatology. Symposium proceedings.

[35]  Lippincott-Schwartz,et al.  5 analysis of secretory protein trafficking within living cells , 1999, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[36]  Bobrow,et al.  9 enhanced tyramide signal amplification immunohistochemical detection , 1999, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[37]  R. Paus,et al.  The Skin POMC System (SPS): Leads and Lessons from the Hair Follicle , 1999, Annals of the New York Academy of Sciences.

[38]  R Paus,et al.  The biology of hair follicles. , 1999, The New England journal of medicine.

[39]  R. Paus,et al.  What controls hair follicle cycling? , 1999, Experimental dermatology.

[40]  Song,et al.  Peptide‐receptive class I major histocompatibility complex molecules on TAP‐deficient and wild‐type cells and their roles in the processing of exogenous antigens , 1999, Immunology.

[41]  J. Mazurkiewicz,et al.  Expression of proopiomelanocortin (POMC)-derived melanocyte-stimulating hormone (MSH) and adrenocorticotropic hormone (ACTH) peptides in skin of basal cell carcinoma patients. , 1999, Human pathology.

[42]  E. Prens,et al.  Interferon‐γ‐induced ICAM‐1 and CD40 expression, complete lack of HLA‐DR and CD80 (B7.1), and inconsistent HLA‐ABC expression in basal cell carcinoma: a possible role for interleukin‐10? , 1999 .

[43]  E. Bandrés,et al.  α-MSH regulates interleukin-10 expression by human keratinocytes , 1998, Archives of Dermatological Research.

[44]  R. Paus,et al.  MHC class I expression in murine skin: developmentally controlled and strikingly restricted intraepithelial expression during hair follicle morphogenesis and cycling, and response to cytokine treatment in vivo. , 1998, The Journal of investigative dermatology.

[45]  S. Eichmüller,et al.  Generation and cyclic remodeling of the hair follicle immune system in mice. , 1998, The Journal of investigative dermatology.

[46]  R. Paus,et al.  Cutaneous Immunomodulation and Coordination of Skin Stress Responses by α‐Melanocyte‐Stimulating Hormone a , 1998 .

[47]  Carina,et al.  Analysis of apoptosis during hair follicle regression (catagen) , 1997, The American journal of pathology.

[48]  T. Kealey,et al.  The role of IGF-I in human skin and its appendages: morphogen as well as mitogen? , 1997, The Journal of investigative dermatology.

[49]  K. McElwee,et al.  Topical FK506: a potent immunotherapy for alopecia areata? Studies using the Dundee experimental bald rat model , 1997, The British journal of dermatology.

[50]  J. Streilein,et al.  Aqueous humor induces transforming growth factor-beta (TGF-beta)-producing regulatory T-cells. , 1997, Current eye research.

[51]  R. Paus,et al.  Hair cycle-dependent changes in the gene expression and protein content of transforming factor β1 and β3 in murine skin , 1997, Archives of Dermatological Research.

[52]  R. Dummer,et al.  Interleukin‐10 is a growth factor for human melanoma cells and down‐regulates HLA class‐I, HLA class‐II and ICAM‐1 molecules , 1997, International journal of cancer.

[53]  J. M. Lipton,et al.  Anti-inflammatory actions of the neuroimmunomodulator α-MSH , 1997 .

[54]  R. Happle,et al.  Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata , 1996, Archives of Dermatological Research.

[55]  A. Gottlieb,et al.  The insulin-like growth factor 1 receptor is expressed by epithelial cells with proliferative potential in human epidermis and skin appendages: correlation of increased expression with epidermal hyperplasia. , 1996, The Journal of investigative dermatology.

[56]  A. Ansari,et al.  Comparative study of the role of professional versus semiprofessional or nonprofessional antigen presenting cells in the rejection of vascularized organ allografts. , 1995, Transplant immunology.

[57]  W. Yeudall,et al.  Effects of transforming growth factor beta-1 on growth-regulatory genes in tumour-derived human oral keratinocytes. , 1995, British Journal of Cancer.

[58]  G. Werther,et al.  Insulin-like growth factor-I and epidermal growth factor regulate insulin-like growth factor binding protein-3 (IGFBP-3) in the human keratinocyte cell line HaCaT. , 1995, The Journal of investigative dermatology.

[59]  H. Matsue,et al.  The effects of cyclosporin A and FK506 on proliferation and IL-8 production of cultured human keratinocytes. , 1995, Journal of dermatological science.

[60]  H. Wu,et al.  Interferon regulatory factor element and interferon regulatory factor 1 in the induction of major histocompatibility complex class I genes in neural cells. , 1995, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

[61]  J. Miyazaki,et al.  Transgenic expression of IL-10 in pancreatic islet A cells accelerates autoimmune insulitis and diabetes in non-obese diabetic mice. , 1994, International immunology.

[62]  S. Eichmüller,et al.  Expression of classical and non‐classical MHC class I antigens in murine hair follicles , 1994, The British journal of dermatology.

[63]  T. Kealey,et al.  Human hair growth in vitro: a model for the study of hair follicle biology. , 1994, Journal of dermatological science.

[64]  T. Kealey,et al.  Effects of insulin and insulin-like growth factors on cultured human hair follicles: IGF-I at physiologic concentrations is an important regulator of hair follicle growth in vitro. , 1994, The Journal of investigative dermatology.

[65]  F. Calzetti,et al.  Interleukin 10 (IL-10) upregulates IL-1 receptor antagonist production from lipopolysaccharide-stimulated human polymorphonuclear leukocytes by delaying mRNA degradation , 1994, The Journal of experimental medicine.

[66]  S. Eichmüller,et al.  Distribution and changing density of gamma‐delta T cells in murine skin during the induced hair cycle , 1994, The British journal of dermatology.

[67]  R. Paus,et al.  Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb? , 1993, The Yale journal of biology and medicine.

[68]  J. Streilein,et al.  Immune privilege as the result of local tissue barriers and immunosuppressive microenvironments. , 1993, Current opinion in immunology.

[69]  R. Paus,et al.  On the potential role of proopiomelanocortin in skin physiology and pathology , 1993, Molecular and Cellular Endocrinology.

[70]  M. Saji,et al.  Hormonal regulation of major histocompatibility complex class I genes in rat thyroid FRTL-5 cells: thyroid-stimulating hormone induces a cAMP-mediated decrease in class I expression. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[71]  W. Gibson,et al.  Immune privilege in hair growth. , 1991, The Journal of investigative dermatology.

[72]  D. Tobin,et al.  Cell Degeneration in Alopecia Areata: An Ultrastructural Study , 1991, The American Journal of dermatopathology.

[73]  M. Green,et al.  Human hair growth in vitro. , 1990, Journal of cell science.

[74]  D. Vergani,et al.  Class I and class II major histocompatibility complex antigen expression on hepatocytes: A study in children with liver disease , 1990, Hepatology.

[75]  T. Mosmann,et al.  Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones , 1989, The Journal of experimental medicine.

[76]  V. Barnaba,et al.  Expression of class I and class II major histocompatibility complex antigens on human hepatocytes , 1988, Hepatology.

[77]  M. Mihm,et al.  Distribution of major histocompatibility antigens in normal skin. , 1986, The British journal of dermatology.

[78]  M. Mihm,et al.  Distribution of major histocompatibility antigens in normal skin , 1983 .

[79]  S. Bernasconi,et al.  The Effect of α-MSH on Plasma Growth Hormone, Cortisol and TSH in Children , 1975 .

[80]  W. Silvers,et al.  A biologist's reflections on dermatology. , 1971, The Journal of investigative dermatology.

[81]  A. Lerner,et al.  Effect of Alpha- and Beta-Melanocyte Stimulating Hormones on the Skin Colour of Man , 1961, Nature.

[82]  E. Weiss,et al.  Allelic variation in HLA-B and HLA-C sequences and the evolution of the HLA-B alleles , 2004, Immunogenetics.

[83]  M. Bouvier Accessory proteins and the assembly of human class I MHC molecules: a molecular and structural perspective. , 2003, Molecular immunology.

[84]  Robert Tampé,et al.  The transporter associated with antigen processing: function and implications in human diseases. , 2002, Physiological reviews.

[85]  J. M. Lipton,et al.  alpha-Melanocyte-stimulating hormone protects the allograft in experimental heart transplantation. , 2002, Transplantation.

[86]  D. Munn,et al.  Immunology at the maternal-fetal interface: lessons for T cell tolerance and suppression. , 2000, Annual review of immunology.

[87]  James T. Elder,et al.  Maintenance of human skin in organ culture: role for insulin-like growth factor-1 receptor and epidermal growth factor receptor , 1999, Archives of Dermatological Research.

[88]  P. Cresswell,et al.  Mechanisms of MHC class I--restricted antigen processing. , 1998, Annual review of immunology.

[89]  S. Kawana,et al.  The FASEB Journal express article 10.1096/fj.01-0254-fje. Published online August 17, 2001. In situ expression of corticotropin-releasing hormone (CRH) and proopiomelanocortin (POMC) genes in human skin , 2022 .