Improved oral bioavailability of anticancer drug tamoxifen through complexation with water soluble cyclodextrins: in vitro and in vivo evaluation

[1]  I. Vhora,et al.  Development of Hot Melt Extruded Solid Dispersion of Tamoxifen Citrate and Resveratrol for Synergistic Effects on Breast Cancer Cells , 2018, AAPS PharmSciTech.

[2]  M. Longhi,et al.  Diloxanide furoate binary complexes with β-, methyl-β-, and hydroxypropyl-β-cyclodextrins: inclusion mode, characterization in solution and in solid state and in vitro dissolution studies , 2018, Pharmaceutical development and technology.

[3]  O. Adeoye,et al.  Cyclodextrins as excipients in tablet formulations. , 2018, Drug discovery today.

[4]  O. Adeoye,et al.  Cyclodextrin nanosystems in oral drug delivery: A mini review. , 2017, International journal of pharmaceutics.

[5]  I. Vhora,et al.  Cholecalciferol-PEG Conjugate Based Nanomicelles of Doxorubicin for Treatment of Triple-Negative Breast Cancer , 2017, AAPS PharmSciTech.

[6]  P. Schwartz,et al.  Regulatory Notes on Impact of Excipients on Drug Products and the Maillard Reaction , 2017, AAPS PharmSciTech.

[7]  Feihe Huang,et al.  Enhancing the solubility and bioactivity of anticancer drug tamoxifen by water-soluble pillar[6]arene-based host-guest complexation. , 2017, Chemical communications.

[8]  M. Ebrahimi,et al.  Preparation, characterization and in‐vivo evaluation of microemulsions containing tamoxifen citrate anti‐cancer drug , 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[9]  Sanyog Jain,et al.  Improved Oral Bioavailability, Therapeutic Efficacy, and Reduced Toxicity of Tamoxifen-Loaded Liquid Crystalline Nanoparticles , 2017, AAPS PharmSciTech.

[10]  F. Kesisoglou,et al.  Amorphous Solid Dispersions or Prodrugs: Complementary Strategies to Increase Drug Absorption. , 2016, Journal of pharmaceutical sciences.

[11]  N. Sharma,et al.  Exploring versatile applications of cyclodextrins: an overview , 2016, Drug delivery.

[12]  Peixiang Wang,et al.  A pre-formulation study of a polymeric solid dispersion of paclitaxel prepared using a quasi-emulsion solvent diffusion method to improve the oral bioavailability in rats , 2016, Drug development and industrial pharmacy.

[13]  K. Sawant,et al.  Formulation of cyclodextrin inclusion complex-based orally disintegrating tablet of eslicarbazepine acetate for improved oral bioavailability. , 2016, Materials science & engineering. C, Materials for biological applications.

[14]  Xingwang Zhang,et al.  Nanosuspensions Containing Oridonin/HP-β-Cyclodextrin Inclusion Complexes for Oral Bioavailability Enhancement via Improved Dissolution and Permeability , 2016, AAPS PharmSciTech.

[15]  B. Gidwani,et al.  A Comprehensive Review on Cyclodextrin-Based Carriers for Delivery of Chemotherapeutic Cytotoxic Anticancer Drugs , 2015, BioMed research international.

[16]  B. Alexander,et al.  Preparation of olanzapine and methyl-β-cyclodextrin complexes using a single-step, organic solvent-free supercritical fluid process: An approach to enhance the solubility and dissolution properties. , 2015, International journal of pharmaceutics.

[17]  Mohamed A. Shaker,et al.  Cellular uptake, cytotoxicity and in-vivo evaluation of Tamoxifen citrate loaded niosomes. , 2015, International journal of pharmaceutics.

[18]  B. Alexander,et al.  Influence of the preparation method on the physicochemical properties of indomethacin and methyl-β-cyclodextrin complexes. , 2015, International journal of pharmaceutics.

[19]  V. Junyaprasert,et al.  Nanocrystals for enhancement of oral bioavailability of poorly water-soluble drugs , 2015 .

[20]  S. Jena,et al.  Development of tamoxifen-phospholipid complex: novel approach for improving solubility and bioavailability. , 2014, International journal of pharmaceutics.

[21]  G. Ji,et al.  Development of a myricetin/hydroxypropyl-β-cyclodextrin inclusion complex: preparation, characterization, and evaluation. , 2014, Carbohydrate polymers.

[22]  Shivendra V. Singh,et al.  Cholesterol depletion by methyl-β-cyclodextrin augments tamoxifen induced cell death by enhancing its uptake in melanoma , 2014, Molecular Cancer.

[23]  V. Patravale,et al.  Tamoxifen nanostructured lipid carriers: enhanced in vivo antitumor efficacy with reduced adverse drug effects. , 2014, International journal of pharmaceutics.

[24]  L. Szente,et al.  Methyl-beta-cyclodextrins: the role of number and types of substituents in solubilizing power. , 2014, Journal of pharmaceutical sciences.

[25]  A. Dahan,et al.  Oral Delivery of Lipophilic Drugs: The Tradeoff between Solubility Increase and Permeability Decrease When Using Cyclodextrin-Based Formulations , 2013, PloS one.

[26]  R. Cavalli,et al.  Cyclodextrin-based nanosponges: effective nanocarrier for Tamoxifen delivery , 2013, Pharmaceutical development and technology.

[27]  P. J. Rolim-Neto,et al.  Inclusion complex of methyl-β-cyclodextrin and olanzapine as potential drug delivery system for schizophrenia. , 2012, Carbohydrate polymers.

[28]  J. Irache,et al.  Molecular buckets: cyclodextrins for oral cancer therapy. , 2012, Therapeutic delivery.

[29]  Koichi Wada,et al.  Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: basic approaches and practical applications. , 2011, International journal of pharmaceutics.

[30]  Z. A. Worku,et al.  Oral formulation strategies to improve solubility of poorly water-soluble drugs , 2011, Expert opinion on drug delivery.

[31]  K. Bouchemal,et al.  Cyclodextrin complexed insulin encapsulated hydrogel microparticles: An oral delivery system for insulin. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[32]  B. Mukherjee,et al.  Tamoxifen Citrate Encapsulated Sustained Release Liposomes: Preparation and Evaluation of Physicochemical Properties , 2010, Scientia pharmaceutica.

[33]  N. Jagannathan,et al.  Tamoxifen-2-hydroxylpropyl-beta-cyclodextrin-aggregated nanoassembly for nonbreast estrogen-receptor-positive cancer therapy. , 2009, Nanomedicine.

[34]  O. Abdallah,et al.  Self-nanoemulsifying drug delivery systems of tamoxifen citrate: design and optimization. , 2009, International journal of pharmaceutics.

[35]  Rajeswari Challa,et al.  Cyclodextrins in drug delivery: An updated review , 2005, AAPS PharmSciTech.

[36]  Vaishali A. Kilor,et al.  Evaluation of some Methods for Preparing Gliclazide-β-Cyclodextrin Inclusion Complexes , 2007 .

[37]  B. Suhagia,et al.  Preparation and characterization of etoricoxib-β-cyclodextrin complexes prepared by the kneading method , 2007, Acta pharmaceutica.

[38]  M. Wempe,et al.  Pharmacokinetics of tamoxifen after intravenous and oral dosing of tamoxifen-hydroxybutenyl-beta-cyclodextrin formulations. , 2007, Journal of pharmaceutical sciences.

[39]  M. Šen,et al.  Complexation behavior of antiestrogen drug tamoxifen citrate with natural and modified β-cyclodextrins , 2007 .

[40]  Sang-Chul Shin,et al.  Enhanced bioavailability of tamoxifen after oral administration of tamoxifen with quercetin in rats. , 2006, International journal of pharmaceutics.

[41]  G. Mellgren,et al.  Identification and quantification of tamoxifen and four metabolites in serum by liquid chromatography-tandem mass spectrometry. , 2005, Journal of chromatography. A.

[42]  S. Lesieur,et al.  Cyclodextrin-Mediated Drug Release from Liposomes Dispersed Within a Bioadhesive Gel , 2005, Pharmaceutical Research.

[43]  M. Másson,et al.  Cyclodextrins in drug delivery , 2005, Expert opinion on drug delivery.

[44]  D. Stevenson,et al.  The bioavailability of Tamoplex® (tamoxifen) , 1988, Pharmaceutisch Weekblad.

[45]  Mark E. Davis,et al.  Cyclodextrin-based pharmaceutics: past, present and future , 2004, Nature Reviews Drug Discovery.

[46]  M. Fibbioli,et al.  The degree of predictivity in pilot studies on six subjects in bioequivalence trials. , 2004, Pharmacological research.

[47]  V. Stella,et al.  Effect of Cyclodextrin Charge on Complexation of Neutral and Charged Substrates: Comparison of (SBE)7M-β-CD to HP-β-CD , 2001, Pharmaceutical Research.

[48]  V. Jordan,et al.  Selective estrogen receptor modulators (SERMS) and their roles in breast cancer prevention. , 2002, Trends in molecular medicine.

[49]  V. Stella,et al.  Effect of cyclodextrin charge on complexation of neutral and charged substrates: comparison of (SBE)7M-beta-CD to HP-beta-CD. , 2001, Pharmaceutical research.

[50]  A. Marzo Crossover Design in Tamoxifen Bioequivalence: a Borderline Situation , 1998, The Journal of pharmacy and pharmacology.

[51]  M. Másson,et al.  Stabilisation of ionic drugs through complexation with non-ionic and ionic cyclodextrins , 1998 .

[52]  K. Uekama,et al.  Pharmaceutical applications of cyclodextrins. III. Toxicological issues and safety evaluation. , 1997, Journal of pharmaceutical sciences.

[53]  D O Thompson,et al.  Cyclodextrins--enabling excipients: their present and future use in pharmaceuticals. , 1997, Critical reviews in therapeutic drug carrier systems.

[54]  G. Williams,et al.  Major difference in the hepatocarcinogenicity and DNA adduct forming ability between toremifene and tamoxifen in female Crl:CD(BR) rats. , 1993, Cancer research.

[55]  J. Mcvie,et al.  The bioavailability of Tamoplex (tamoxifen). Part 1. A pilot study. , 1986, Methods and findings in experimental and clinical pharmacology.