Focus defect and dispersion mismatch in full-field optical coherence microscopy.

Full-field optical coherence microscopy (FFOCM) is an optical technique, based on low-coherence interference microscopy, for tomographic imaging of semi-transparent samples with micrometer-scale spatial resolution. The differences in refractive index between the sample and the immersion medium of the microscope objectives may degrade the FFOCM image quality because of focus defect and optical dispersion mismatch. These phenomena and their consequences are discussed in this theoretical paper. Experimental methods that have been implemented in FFOCM to minimize the adverse effects of these phenomena are summarized and compared.

[1]  Sheng-Lung Huang,et al.  Full-depth epidermis tomography using a Mirau-based full-field optical coherence tomography. , 2014, Biomedical optics express.

[2]  B E Bouma,et al.  Ultrahigh-resolution full-field optical coherence microscopy using InGaAs camera. , 2006, Optics express.

[3]  P. Georges,et al.  Motion artifact suppression in full-field optical coherence tomography. , 2010, Applied optics.

[4]  A. Claude Boccara,et al.  In vivo and in situ cellular imaging full-field optical coherence tomography with a rigid endoscopic probe , 2011, Biomedical optics express.

[5]  Sheng-Hua Lu,et al.  Full-field optical coherence tomography using immersion Mirau interference microscope. , 2013, Applied optics.

[6]  C. Boccara,et al.  Rapid evaluation of fresh ex vivo kidney tissue with full-field optical coherence tomography , 2015, Journal of pathology informatics.

[7]  Martin J Booth,et al.  Image based adaptive optics through optimisation of low spatial frequencies. , 2007, Optics express.

[8]  G. J. Brakenhoff,et al.  Refractive index and axial distance measurements in 3-D microscopy , 1992 .

[9]  V. Ryabukho,et al.  Polychromatic low-coherence interferometry of stratified structures with digital interferogram recording and processing , 2011 .

[10]  Ultrahigh-resolution full-field optical coherence tomography using spatial coherence gating and quasi-monochromatic illumination. , 2012, Optics letters.

[11]  A. Boccara,et al.  Thermal-light full-field optical coherence tomography. , 2002, Optics letters.

[12]  C. Sheppard,et al.  Effects of specimen refractive index on confocal imaging , 1997 .

[13]  H Saint-Jalmes,et al.  Full-field optical coherence microscopy. , 1998, Optics letters.

[14]  C K Hitzenberger,et al.  Dispersion effects in partial coherence interferometry: implications for intraocular ranging. , 1999, Journal of biomedical optics.

[15]  K Grieve,et al.  Three-dimensional cellular-level imaging using full-field optical coherence tomography. , 2004, Physics in medicine and biology.

[16]  C. Boccara,et al.  Ultrahigh-resolution full-field optical coherence tomography. , 2004, Applied optics.

[17]  Marcos Dantus,et al.  Group-velocity dispersion measurements of water, seawater, and ocular components using multiphoton intrapulse interference phase scan. , 2007, Applied optics.

[18]  A. Boccara,et al.  High-resolution full-field optical coherence tomography with a Linnik microscope. , 2002, Applied optics.

[19]  I. Abdulhalim.  Theory for double beam interference microscopes with coherence effects and verification using the linnik microscope , 2001 .

[20]  Antoine Federici,et al.  Three-band, 1.9-μm axial resolution full-field optical coherence microscopy over a 530-1700 nm wavelength range using a single camera. , 2014, Optics letters.

[21]  Antoine Federici,et al.  Full-field optical coherence microscopy with optimized ultrahigh spatial resolution. , 2015, Optics letters.

[22]  Ibrahim Abdulhalim,et al.  Competence between spatial and temporal coherence in full field optical coherence tomography and interference microscopy , 2006 .

[23]  A. Boccara,et al.  Defocus test and defocus correction in full-field optical coherence tomography. , 2009, Optics letters.

[24]  Antonello De Martino,et al.  Full-field optical coherence tomography with thermal light. , 2002, Applied optics.

[25]  W J Tango.  Dispersion in stellar interferometry. , 1990, Applied optics.

[26]  Claude Boccara,et al.  Thermal-light full-field optical coherence tomography in the 1.2 μm wavelength region , 2006 .

[27]  Ibrahim Abdulhalim,et al.  Spatial coherence effect on layer thickness determination in narrowband full-field optical coherence tomography. , 2011, Applied optics.

[28]  D. Salomon,et al.  Full-Field Optical Coherence Tomography: A New Technology for 3D High-Resolution Skin Imaging , 2012, Dermatology.

[29]  J M Schmitt,et al.  Turbulent nature of refractive-index variations in biological tissue. , 1996, Optics letters.

[30]  A. Boccara,et al.  Early chloroplastic alterations analysed by optical coherence tomography during a harpin-induced hypersensitive response. , 2007, The Plant journal : for cell and molecular biology.

[31]  Lingfeng Yu,et al.  Full-color three-dimensional microscopy by wide-field optical coherence tomography. , 2004, Optics express.

[32]  A. Boccara,et al.  Polarization-sensitive full-field optical coherence tomography. , 2007, Optics letters.

[33]  Kate Grieve,et al.  Ocular tissue imaging using ultrahigh-resolution, full-field optical coherence tomography. , 2004, Investigative ophthalmology & visual science.

[34]  B. Devaux,et al.  Imaging of non-tumorous and tumorous human brain tissues with full-field optical coherence tomography☆ , 2013, NeuroImage: Clinical.

[35]  Yu-Min Lin,et al.  Applying RGB LED in full-field optical coherence tomography for real-time full-color tissue imaging. , 2014, Applied optics.

[36]  I. Zeylikovich.  Short coherence length produced by a spatial incoherent source applied for the Linnik-type interferometer. , 2008, Applied optics.

[37]  B L Danielson,et al.  Absolute optical ranging using low coherence interferometry. , 1991, Applied optics.

[38]  Patrick Georges,et al.  Simultaneous dual-band ultra-high resolution full-field optical coherence tomography. , 2008, Optics express.

[39]  High-resolution full-field optical coherence microscopy using a broadband light-emitting diode. , 2016, Optics express.

[40]  G S Kino,et al.  Mirau correlation microscope. , 1990, Applied optics.

[41]  Egidijus Auksorius,et al.  Dark-field full-field optical coherence tomography. , 2015, Optics letters.

[42]  Houssine Makhlouf,et al.  Simultaneous optically sectioned fluorescence and optical coherence microscopy with full-field illumination. , 2012, Optics letters.

[43]  A. Boccara,et al.  Stroboscopic ultrahigh-resolution full-field optical coherence tomography. , 2005, Optics letters.

[44]  S. Hell,et al.  Aberrations in confocal fluorescence microscopy induced by mismatches in refractive index , 1993 .

[45]  C. Boccara,et al.  Spectroscopic ultrahigh-resolution full-field optical coherence microscopy. , 2008, Optics express.

[46]  J. Fujimoto,et al.  In vivo ultrahigh-resolution optical coherence tomography. , 1999, Optics letters.

[47]  Ibrahim Abdulhalim,et al.  Spatial and temporal coherence effects in interference microscopy and full‐field optical coherence tomography , 2012 .