Rationally engineered Cas9 nucleases with improved specificity
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David A. Scott | Feng Zhang | Linyi Gao | F. Zhang | I. Slaymaker | Bernd Zetsche | Winston X. Yan | L. Gao | David A. Scott
[1] Albert J R Heck,et al. RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions , 2011, Proceedings of the National Academy of Sciences.
[2] Konstantin Severinov,et al. Interference by clustered regularly interspaced short palindromic repeat (CRISPR) RNA is governed by a seed sequence , 2011, Proceedings of the National Academy of Sciences.
[3] Shane S. Sturrock,et al. Geneious Basic: An integrated and extendable desktop software platform for the organization and analysis of sequence data , 2012, Bioinform..
[4] Eli J. Fine,et al. DNA targeting specificity of RNA-guided Cas9 nucleases , 2013, Nature Biotechnology.
[5] M. Rowicka,et al. Nucleotide-resolution DNA double-strand breaks mapping by next-generation sequencing , 2013, Nature Methods.
[6] Feng Zhang,et al. CRISPR-assisted editing of bacterial genomes , 2013, Nature Biotechnology.
[7] Le Cong,et al. Multiplex Genome Engineering Using CRISPR/Cas Systems , 2013, Science.
[8] G. Church,et al. CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering , 2013, Nature Biotechnology.
[9] James E. DiCarlo,et al. RNA-Guided Human Genome Engineering via Cas9 , 2013, Science.
[10] David A. Scott,et al. Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity , 2013, Cell.
[11] J. Keith Joung,et al. High frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells , 2013, Nature Biotechnology.
[12] Martin J. Aryee,et al. Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing , 2014, Nature Biotechnology.
[13] M. Jinek,et al. Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease , 2014, Nature.
[14] David R. Liu,et al. Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification , 2014, Nature Biotechnology.
[15] J. Keith Joung,et al. Improving CRISPR-Cas nuclease specificity using truncated guide RNAs , 2014, Nature Biotechnology.
[16] Feng Zhang,et al. Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA , 2014, Cell.
[17] Ken W. Y. Cho,et al. Targeted genome editing in human cells using CRISPR/Cas nucleases and truncated guide RNAs. , 2014, Methods in enzymology.
[18] Jennifer A. Doudna,et al. DNA interrogation by the CRISPR RNA-guided endonuclease Cas9 , 2014, Nature.
[19] David R. Liu,et al. Small Molecule-Triggered Cas9 Protein with Improved Genome-Editing Specificity , 2015, Nature chemical biology.
[20] David A. Scott,et al. In vivo genome editing using Staphylococcus aureus Cas9 , 2015, Nature.
[21] Martin J. Aryee,et al. GUIDE-Seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases , 2014, Nature Biotechnology.
[22] Feng Zhang,et al. A split-Cas9 architecture for inducible genome editing and transcription modulation , 2015, Nature Biotechnology.