Cyclical ischaemic preconditioning modulates the adaptive immune response in human limb ischaemia–reperfusion injury

Reperfusion injury (RI) has significant local and systemic consequences. Ischaemic preconditioning (IPC) modulates RI and the innate immune response. This study examined whether IPC attenuates RI‐mediated changes in lymphocyte populations and function following elective surgery.

[1]  Bhagwan Satiani,et al.  No-show rates in the vascular laboratory: analysis and possible solutions. , 2009, Journal of vascular and interventional radiology : JVIR.

[2]  Z. Ali,et al.  Remote Ischemic Preconditioning Reduces Myocardial and Renal Injury After Elective Abdominal Aortic Aneurysm Repair: A Randomized Controlled Trial , 2007, Circulation.

[3]  T. Annecke,et al.  Effects of sevoflurane and propofol on ischaemia-reperfusion injury after thoracic-aortic occlusion in pigs. , 2007, British journal of anaesthesia.

[4]  Yaqin Xu,et al.  Myocardial Infarct–Sparing Effect of Adenosine A2A Receptor Activation Is due to Its Action on CD4+ T Lymphocytes , 2006, Circulation.

[5]  I. Konstantinov,et al.  Randomized controlled trial of the effects of remote ischemic preconditioning on children undergoing cardiac surgery: first clinical application in humans. , 2006, Journal of the American College of Cardiology.

[6]  J. Bonanno,et al.  Hypoxia preconditioning protects corneal stromal cells against induced apoptosis. , 2006, Experimental eye research.

[7]  M. Wadman London's disastrous drug trial has serious side effects for research , 2006, Nature.

[8]  G. Shaw,et al.  Molecular Characterization of Rat Leukocyte P-Selectin Glycoprotein Ligand-1 and Effect of Its Blockade: Protection from Ischemia-Reperfusion Injury in Liver Transplantation1 , 2006, The Journal of Immunology.

[9]  C. Edelstein,et al.  Peripheral CD4 T-Cell Depletion Is Not Sufficient to Prevent Ischemic Acute Renal Failure , 2005, Transplantation.

[10]  H. Rabb,et al.  Effects of Combined T‐ and B‐Cell Deficiency on Murine Ischemia Reperfusion Injury , 2005, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[11]  Bozena Kaminska,et al.  Influence of chemical and ischemic preconditioning on cytokine expression after focal brain ischemia , 2004, Journal of neuroscience research.

[12]  M. D. de Broe,et al.  T cells as mediators in renal ischemia/reperfusion injury. , 2004, Kidney international.

[13]  S. Holland,et al.  Extra-cellular superoxide promotes T cell expansion through inactivation of nitric oxide , 2004, Journal of Neuroimmunology.

[14]  M. Miyazaki,et al.  Interleukin 18 causes hepatic ischemia/reperfusion injury by suppressing anti‐inflammatory cytokine expression in mice , 2004, Hepatology.

[15]  D. Granger,et al.  T‐Lymphocytes Modulate the Microvascular and Inflammatory Responses to Intestinal Ischemia‐Reperfusion , 2002, Microcirculation.

[16]  J. Alexander,et al.  Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes. , 2002, American journal of physiology. Renal physiology.

[17]  P. Vallance,et al.  Ischemic preconditioning prevents endothelial injury and systemic neutrophil activation during ischemia-reperfusion in humans in vivo. , 2001, Circulation.

[18]  M. Raffaelli,et al.  The Hemodynamic and Metabolic Effects of Tourniquet Application During Knee Surgery , 2000, Anesthesia and analgesia.

[19]  J. Mouiel,et al.  Caspase inhibition protects from liver injury following ischemia and reperfusion in rats , 2000, Transplant international : official journal of the European Society for Organ Transplantation.

[20]  G. Zibari,et al.  Both ischemic and pharmacological preconditioning decrease hepatic leukocyte/endothelial cell interactions. , 1999, Transplantation.

[21]  A. Lentsch,et al.  Requirement for interleukin‐12 in the pathogenesis of warm hepatic ischemia/reperfusion injury in mice , 1999, Hepatology.

[22]  J. Martini,et al.  Ischemic preconditioning attenuates ischemia/reperfusion-induced activation of caspases and subsequent cleavage of poly(ADP-ribose) polymerase in rat hearts in vivo. , 1999, Cardiovascular research.

[23]  M. Sugaya,et al.  Interleukins 18 and 12 synergistically upregulate interferon-gamma production by murine dendritic epidermal T cells. , 1999, The Journal of investigative dermatology.

[24]  F. Luscinskas,et al.  Acquisition of Selectin Binding and Peripheral Homing Properties by CD4+ and CD8+ T Cells , 1999, The Journal of experimental medicine.

[25]  D. Yellon,et al.  Myocardial adaptation to ischaemia--the preconditioning phenomenon. , 1999, International journal of cardiology.

[26]  M. Al-Qattan Ischaemia-Reperfusion Injury , 1998 .

[27]  Ethan M. Shevach,et al.  CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 Production , 1998, The Journal of experimental medicine.

[28]  R. Korthuis,et al.  MECHANISMS OF ISCHEMIC PRECONDITIONING , 1997, Shock.

[29]  J. Engelhardt,et al.  CD4(+) T-lymphocytes mediate ischemia/reperfusion-induced inflammatory responses in mouse liver. , 1997, The Journal of clinical investigation.

[30]  P. Norman,et al.  Immunobiology: The immune system in health and disease , 1995 .

[31]  D. Yellon,et al.  Protein kinase C. Its role in ischemic preconditioning in the rat. , 1994, Circulation research.

[32]  D. Lancki,et al.  Differential regulation of murine T lymphocyte subsets. , 1993, Annual review of immunology.

[33]  R. Coffman,et al.  CD4+ T-cell subsets: regulation of differentiation and function. , 1991, Research in immunology.

[34]  R. Berne,et al.  Adenosine stimulates glycolytic flux in isolated perfused rat hearts by A1-adenosine receptors. , 1989, The American journal of physiology.

[35]  M. Grisham,et al.  Adenosine inhibits ischemia-reperfusion-induced leukocyte adherence and extravasation. , 1989, The American journal of physiology.

[36]  J. Mannick,et al.  Noncardiogenic Pulmonary Edema After Abdominal Aortic Aneurysm Surgery , 1989, Annals of surgery.

[37]  C. Valeri,et al.  Reperfusion of ischemic lower limbs increases pulmonary microvascular permeability. , 1988, The Journal of trauma.

[38]  R. Jennings,et al.  Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. , 1986, Circulation.

[39]  I. Clark,et al.  Effect of antioxidants on primary alloantigen-induced T cell activation and proliferation. , 1986, Journal of immunology.

[40]  G. Weissmann,et al.  Adenosine: an endogenous inhibitor of neutrophil-mediated injury to endothelial cells. , 1986, The Journal of clinical investigation.

[41]  S. Miller,et al.  Effects of tourniquet ischemia and postischemic edema on muscle metabolism. , 1979, The Journal of hand surgery.