The role of UNC5C in Alzheimer's disease.
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L. Tan | Quan Li | Bai-Ling Wang | Fu-Rong Sun | Jieqiong Li | Xipeng Cao
[1] Brian J Cummings,et al. Immunohistochemical evidence for apoptosis in Alzheimer's disease. , 1994, Neuroreport.
[2] J. Mandell,et al. Microtubule-associated proteins, phosphorylation gradients, and the establishment of neuronal polarity. , 1996, Perspectives on developmental neurobiology.
[3] S. Takeda,et al. G Protein-Mediated Neuronal DNA Fragmentation Induced by Familial Alzheimer's Disease-Associated Mutants of APP , 1996, Science.
[4] M. Masu,et al. Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors , 1997, Nature.
[5] S. Ackerman,et al. Cloning and mapping of the UNC5C gene to human chromosome 4q21-q23. , 1998, Genomics.
[6] D. Bredesen,et al. The RET proto‐oncogene induces apoptosis: a novel mechanism for Hirschsprung disease , 2000, The EMBO journal.
[7] F. Llambi,et al. Netrin‐1 acts as a survival factor via its receptors UNC5H and DCC , 2001, The EMBO journal.
[8] P. Mehlen,et al. Inhibition of Neuroepithelial Patched-Induced Apoptosis by Sonic Hedgehog , 2003, Science.
[9] Ken Watanabe,et al. UNC5H1 Induces Apoptosis via Its Juxtamembrane Region through an Interaction with NRAGE* , 2003, The Journal of Biological Chemistry.
[10] Giovanni Romeo,et al. The netrin-1 receptors UNC5H are putative tumor suppressors controlling cell death commitment , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[11] G. Johnson,et al. Tau phosphorylation in neuronal cell function and dysfunction , 2004, Journal of Cell Science.
[12] I. Nishimoto,et al. Transforming Growth Factor (cid:2) 2 Is a Neuronal Death-Inducing Ligand for Amyloid- (cid:2) Precursor Protein , 2005 .
[13] Taylor J. Maxwell,et al. DAPK1 variants are associated with Alzheimer's disease and allele-specific expression. , 2006, Human molecular genetics.
[14] N. Matsubara,et al. Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer. , 2007, Gastroenterology.
[15] E. Bruyneel,et al. Opposing roles of netrin-1 and the dependence receptor DCC in cancer cell invasion, tumor growth and metastasis , 2007, Oncogene.
[16] A. Kimchi,et al. DAP kinase regulates JNK signaling by binding and activating protein kinase D under oxidative stress , 2007, Cell Death and Differentiation.
[17] P. Mehlen,et al. Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B , 2008, Nature Cell Biology.
[18] M. Wilkinson,et al. Epigenetic regulation and downstream targets of the Rhox5 homeobox gene. , 2008, International journal of andrology.
[19] D. Bredesen,et al. Netrin-1 interacts with amyloid precursor protein and regulates amyloid-β production , 2009, Cell Death and Differentiation.
[20] M. Hoshino,et al. Dissecting the Factors Involved in the Locomotion Mode of Neuronal Migration in the Developing Cerebral Cortex* , 2009, The Journal of Biological Chemistry.
[21] I. Bejarano,et al. Caspase-3 and -9 are activated in human myeloid HL-60 cells by calcium signal , 2009, Molecular and Cellular Biochemistry.
[22] P. Mehlen,et al. Netrin-1 and its dependence receptors as original targets for cancer therapy , 2010, Current opinion in oncology.
[23] P. Shannon,et al. Exome sequencing identifies the cause of a Mendelian disorder , 2009, Nature Genetics.
[24] Jin-Tai Yu,et al. Association of DAPK1 genetic variations with Alzheimer's disease in Han Chinese , 2011, Brain Research.
[25] P. Wong,et al. Amyloid precursor protein processing and Alzheimer's disease. , 2011, Annual review of neuroscience.
[26] P. Bosco,et al. APOE and Alzheimer disease: a major gene with semi-dominant inheritance , 2011, Molecular Psychiatry.
[27] S. Ackerman,et al. The UNC5C Netrin Receptor Regulates Dorsal Guidance of Mouse Hindbrain Axons , 2011, The Journal of Neuroscience.
[28] M. Barcikowska,et al. Identification of a late onset Alzheimer's disease candidate risk variant at 9q21.33 in Polish patients. , 2012, Journal of Alzheimer's disease : JAD.
[29] Y. Hashimoto,et al. MOCA is an integrator of the neuronal death signals that are activated by familial Alzheimer's disease-related mutants of amyloid β precursor protein and presenilins. , 2012, The Biochemical journal.
[30] H. Nemoto,et al. Methylation of the HACE1 gene is frequently detected in hepatocellular carcinoma. , 2012, Hepato-gastroenterology.
[31] Jingxia Gao,et al. Expression of unc5 family genes in zebrafish brain during embryonic development. , 2013, Gene expression patterns : GEP.
[32] Y. Oh,et al. Netrin-1 protects hypoxia-induced mitochondrial apoptosis through HSP27 expression via DCC- and integrin α6β4-dependent Akt, GSK-3β, and HSF-1 in mesenchymal stem cells , 2013, Cell Death and Disease.
[33] Y. Hashimoto,et al. A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity , 2014, Journal of neurochemistry.
[34] S. Küry,et al. Evaluation of the colorectal cancer risk conferred by rare UNC5C alleles. , 2014, World journal of gastroenterology.
[35] H. Wood. Alzheimer disease: AD-susceptible brain regions exhibit altered DNA methylation , 2014, Nature Reviews Neurology.
[36] F. Terro,et al. Longitudinal follow-up of autophagy and inflammation in brain of APPswePS1dE9 transgenic mice , 2014, Journal of Neuroinflammation.
[37] A. Kimchi,et al. Death-associated protein kinase 1 has a critical role in aberrant tau protein regulation and function , 2014, Cell Death and Disease.
[38] J. Hardy,et al. Apolipoprotein E in Alzheimer's disease: an update. , 2014, Annual review of neuroscience.
[39] J. Haines,et al. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death , 2014, Nature Medicine.
[40] B. Tang,et al. Investigation of TREM2, PLD3, and UNC5C variants in patients with Alzheimer's disease from mainland China , 2014, Neurobiology of Aging.
[41] N. Grishin,et al. An ancient autoproteolytic domain found in GAIN, ZU5 and Nucleoporin98. , 2014, Journal of molecular biology.
[42] E. Palmesino,et al. Synergistic integration of Netrin and ephrin axon guidance signals by spinal motor neurons , 2015, eLife.
[43] Xiao Zhen Zhou,et al. Pin1 dysregulation helps to explain the inverse association between cancer and Alzheimer's disease. , 2015, Biochimica et biophysica acta.
[44] R. Wilson,et al. Alzheimer's disease: rare variants with large effect sizes. , 2015, Current opinion in genetics & development.
[45] L. Farrer. Expanding the genomic roadmap of Alzheimer's disease , 2015, The Lancet Neurology.
[46] Alzheimer's Disease Neuroimaging Initiative,et al. The Impact of UNC5C Genetic Variations on Neuroimaging in Alzheimer’s Disease , 2016, Molecular Neurobiology.
[47] Y. Sugimoto,et al. Molecular Effects of Polymorphism in the 3’UTR of Unc-5 homolog C Associated with Conception Rate in Holsteins , 2015, PloS one.
[48] [GENETIC AND EPIGENETIC DETERMINANTS OF ALZHEIMER'S DISEASE]. , 2015, Advances in gerontology = Uspekhi gerontologii.
[49] O. Korvatska,et al. R47H Variant of TREM2 Associated With Alzheimer Disease in a Large Late-Onset Family: Clinical, Genetic, and Neuropathological Study. , 2015, JAMA neurology.
[50] Michel Goedert,et al. Alzheimer’s and Parkinson’s diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein , 2015, Science.
[51] The Role of MAPT in Neurodegenerative Diseases: Genetics, Mechanisms and Therapy , 2016, Molecular Neurobiology.
[52] The Role of Reelin Signaling in Alzheimer’s Disease , 2016, Molecular Neurobiology.
[53] J. Sanchez-Mut,et al. Epigenetic Alterations in Alzheimer’s Disease , 2015, Front. Behav. Neurosci..
[54] Y. Kiriyama,et al. The Function of Autophagy in Neurodegenerative Diseases , 2015, International journal of molecular sciences.
[55] M. Tsolaki,et al. Recent Findings in Alzheimer Disease and Nutrition Focusing on Epigenetics. , 2016, Advances in nutrition.
[56] Fei Liu,et al. Tau and neurodegenerative disease: the story so far , 2016, Nature Reviews Neurology.
[57] Xiaolong Wang,et al. The Role of 99mTc-Annexin V Apoptosis Scintigraphy in Visualizing Early Stage Glucocorticoid-Induced Femoral Head Osteonecrosis in the Rabbit , 2016, BioMed research international.
[58] W. Klein,et al. Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology , 2016, Acta Neuropathologica.
[59] M. Urioste,et al. Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis , 2016, Scientific Reports.
[60] Y. Hashimoto,et al. An Alzheimer Disease-linked Rare Mutation Potentiates Netrin Receptor Uncoordinated-5C-induced Signaling That Merges with Amyloid β Precursor Protein Signaling* , 2016, The Journal of Biological Chemistry.
[61] Palaniyandi Ravanan,et al. Death Associated Protein Kinase 1 (DAPK1): A Regulator of Apoptosis and Autophagy , 2016, Front. Mol. Neurosci..
[62] L. Cantley,et al. Death-associated protein kinase 1 phosphorylates NDRG2 and induces neuronal cell death , 2016, Cell Death and Differentiation.
[63] J. Attems,et al. Interactions of pathological proteins in neurodegenerative diseases , 2017, Acta Neuropathologica.
[64] L. Saso,et al. Proteinopathy, oxidative stress and mitochondrial dysfunction: cross talk in Alzheimer’s disease and Parkinson’s disease , 2017, Drug design, development and therapy.
[65] Olivier Rouaud,et al. APP, PSEN1, and PSEN2 mutations in early-onset Alzheimer disease: A genetic screening study of familial and sporadic cases , 2017, PLoS medicine.
[66] M. Korte,et al. Not just amyloid: physiological functions of the amyloid precursor protein family , 2017, Nature Reviews Neuroscience.
[67] T. Hartmann,et al. APP Function and Lipids: A Bidirectional Link , 2017, Front. Mol. Neurosci..
[68] J. Herz,et al. ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease , 2017, Trends in Endocrinology & Metabolism.
[69] L. Megeney,et al. Evolution of caspase-mediated cell death and differentiation: twins separated at birth , 2017, Cell Death and Differentiation.
[70] M. Mendez. Early-Onset Alzheimer Disease. , 2017, Neurologic clinics.
[71] Jie Wu,et al. Methylation of the UNC5C gene and its protein expression in colorectal cancer , 2017, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
[72] Toshitaka Nagao,et al. Plaque formation and the intraneuronal accumulation of β‐amyloid in Alzheimer's disease , 2017, Pathology international.