Disruption of desmosome assembly by monovalent human pemphigus vulgaris monoclonal antibodies.
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[1] L. Diaz,et al. E-cadherin is an additional immunological target for pemphigus autoantibodies. , 2008, The Journal of investigative dermatology.
[2] V. Faundez,et al. Pemphigus Vulgaris IgG-induced Desmoglein-3 Endocytosis and Desmosomal Disassembly Are Mediated by a Clathrin- and Dynamin-independent Mechanism* , 2008, Journal of Biological Chemistry.
[3] J. Waschke. The desmosome and pemphigus , 2008, Histochemistry and Cell Biology.
[4] C. Kolly,et al. Outside-in signaling through integrins and cadherins: a central mechanism to control epidermal growth and differentiation? , 2008, The Journal of investigative dermatology.
[5] A. Hopkins,et al. Desmoglein-2: a novel regulator of apoptosis in the intestinal epithelium. , 2007, Molecular biology of the cell.
[6] Preety M. Sharma,et al. Beyond steric hindrance: the role of adhesion signaling pathways in the pathogenesis of pemphigus. , 2007, Journal of dermatological science.
[7] D. Siegel,et al. Targeting pemphigus autoantibodies through their heavy-chain variable region genes. , 2007, The Journal of investigative dermatology.
[8] M. Amagai,et al. Anti-desmoglein 3 (Dsg3) Monoclonal Antibodies Deplete Desmosomes of Dsg3 and Differ in Their Dsg3-depleting Activities Related to Pathogenicity* , 2007, Journal of Biological Chemistry.
[9] D. Zillikens,et al. Inhibition of Rho A activity causes pemphigus skin blistering , 2006, The Journal of cell biology.
[10] M. Amagai,et al. Synergistic pathogenic effects of combined mouse monoclonal anti-desmoglein 3 IgG antibodies on pemphigus vulgaris blister formation. , 2006, The Journal of investigative dermatology.
[11] Masayuki Amagai,et al. Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome. , 2006, The New England journal of medicine.
[12] P. Hu,et al. p38MAPK inhibition prevents disease in pemphigus vulgaris mice , 2006, Proceedings of the National Academy of Sciences.
[13] A. de Bruin,et al. Pemphigus vulgaris identifies plakoglobin as key suppressor of c‐Myc in the skin , 2006, The EMBO journal.
[14] L. Cavacini,et al. Pathogenic human monoclonal antibody against desmoglein 3. , 2006, Clinical immunology.
[15] N. Cirillo,et al. Serum from pemphigus vulgaris reduces desmoglein 3 half‐life and perturbs its de novo assembly to desmosomal sites in cultured keratinocytes , 2006, FEBS letters.
[16] M. Amagai,et al. Desmoglein Endocytosis and Desmosome Disassembly Are Coordinated Responses to Pemphigus Autoantibodies* , 2006, Journal of Biological Chemistry.
[17] P. J. Koch,et al. Desmocollin 3 is required for pre-implantation development of the mouse embryo , 2006, Journal of Cell Science.
[18] Qian-chun Yu,et al. “Free‐Floating” Desmosomes in Lipoid Proteinosis: An Inherent Defect in Keratinocyte Adhesion? , 2006, Pediatric dermatology.
[19] E. Shu,et al. Pemphigus vulgaris-IgG reduces the desmoglein 3/desmocollin 3 ratio on the cell surface in cultured keratinocytes as revealed by double-staining immunoelectron microscopy. , 2005, Journal of dermatological science.
[20] Y. Shirakata,et al. In vitro keratinocyte dissociation assay for evaluation of the pathogenicity of anti-desmoglein 3 IgG autoantibodies in pemphigus vulgaris. , 2005, The Journal of investigative dermatology.
[21] Y. Hanakawa,et al. Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display. , 2005, The Journal of clinical investigation.
[22] B. Pelacho,et al. In vivo blockade of pemphigus vulgaris acantholysis by inhibition of intracellular signal transduction cascades , 2004, The British journal of dermatology.
[23] A. Merritt,et al. Regulation of desmocollin gene expression in the epidermis: CCAAT/enhancer-binding proteins modulate early and late events in keratinocyte differentiation. , 2004, The Biochemical journal.
[24] T. Nishikawa,et al. IgG binds to desmoglein 3 in desmosomes and causes a desmosomal split without keratin retraction in a pemphigus mouse model. , 2004, The Journal of investigative dermatology.
[25] K. Green,et al. Working out the strength and flexibility of desmosomes , 2004, Nature Reviews Molecular Cell Biology.
[26] David L Stokes,et al. Untangling Desmosomal Knots with Electron Tomography , 2003, Science.
[27] J. Ott,et al. Desmoglein 4 in Hair Follicle Differentiation and Epidermal Adhesion Evidence from Inherited Hypotrichosis and Acquired Pemphigus Vulgaris , 2003, Cell.
[28] N. Whittock,et al. Genetic evidence for a novel human desmosomal cadherin, desmoglein 4. , 2003, The Journal of investigative dermatology.
[29] Y. Kitajima. Mechanisms of desmosome assembly and disassembly , 2002, Clinical and experimental dermatology.
[30] I. Burdett,et al. Desmosome assembly in MDCK cells: transport of precursors to the cell surface occurs by two phases of vesicular traffic and involves major changes in centrosome and Golgi location during a Ca(2+) shift. , 2002, Experimental cell research.
[31] Stephen R. Martin,et al. Molecular interactions between desmosomal cadherins. , 2002, The Biochemical journal.
[32] K. Bhol,et al. Production of Non-pathogenic Human Monoclonal Antibodies to Desmoglein 3 from Pemphigus Vulgaris Patient , 2002, Autoimmunity.
[33] E. Fuchs,et al. Desmoplakin is essential in epidermal sheet formation , 2001, Nature Cell Biology.
[34] T. Nishikawa,et al. Dominant Autoimmune Epitopes Recognized by Pemphigus Antibodies Map to the N-Terminal Adhesive Region of Desmogleins1 , 2001, The Journal of Immunology.
[35] M. Pittelkow,et al. Antibodies against keratinocyte antigens other than desmogleins 1 and 3 can induce pemphigus vulgaris-like lesions. , 2000, The Journal of clinical investigation.
[36] T. Nishikawa,et al. Use of domain-swapped molecules for conformational epitope mapping of desmoglein 3 in pemphigus vulgaris. , 2000, The Journal of investigative dermatology.
[37] Y. Aoyama,et al. Assembly Pathway of Desmoglein 3 to Desmosomes and Its Perturbation by Pemphigus Vulgaris-IgG in Cultured Keratinocytes, as Revealed by Time-Lapsed Labeling Immunoelectron Microscopy , 2000, Laboratory Investigation.
[38] S. Grando,et al. Pemphigus Vulgaris Antibody Identifies Pemphaxin , 2000, The Journal of Biological Chemistry.
[39] K. Sayama,et al. Different effects of dominant negative mutants of desmocollin and desmoglein on the cell-cell adhesion of keratinocytes. , 2000, Journal of cell science.
[40] T. Nishikawa,et al. Use of autoantigen-knockout mice in developing an active autoimmune disease model for pemphigus. , 2000, The Journal of clinical investigation.
[41] B. Gumbiner,et al. Regulation of Cadherin Adhesive Activity , 2000, The Journal of cell biology.
[42] A. Magee,et al. Molecular map of the desmosomal plaque. , 1999, Journal of cell science.
[43] Zhi Hong Wang,et al. Explanations for the clinical and microscopic localization of lesions in pemphigus foliaceus and vulgaris. , 1999, The Journal of clinical investigation.
[44] T. Nishikawa,et al. The clinical phenotype of pemphigus is defined by the anti-desmoglein autoantibody profile. , 1999, Journal of the American Academy of Dermatology.
[45] E. Fuchs,et al. Desmoplakin Is Required Early in Development for Assembly of Desmosomes and Cytoskeletal Linkage , 1998, The Journal of cell biology.
[46] C. Marcozzi,et al. Coexpression of both types of desmosomal cadherin and plakoglobin confers strong intercellular adhesion. , 1998, Journal of cell science.
[47] X Ding,et al. Mucosal and mucocutaneous (generalized) pemphigus vulgaris show distinct autoantibody profiles. , 1997, The Journal of investigative dermatology.
[48] T. Nishikawa,et al. Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins. , 1997, Journal of immunology.
[49] S. Troyanovsky,et al. Direct Ca2+-dependent Heterophilic Interaction between Desmosomal Cadherins, Desmoglein and Desmocollin, Contributes to Cell–Cell Adhesion , 1997, The Journal of cell biology.
[50] D. Garrod,et al. Distinct desmocollin isoforms occur in the same desmosomes and show reciprocally graded distributions in bovine nasal epidermis. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[51] E. Fuchs,et al. Mice expressing a mutant desmosomal cadherin exhibit abnormalities in desmosomes, proliferation, and epidermal differentiation , 1996, The Journal of cell biology.
[52] C. Grund,et al. Continual assembly of half-desmosomal structures in the absence of cell contacts and their frustrated endocytosis: a coordinated Sisyphus cycle , 1995, The Journal of cell biology.
[53] M. Amagai,et al. Extracellular domain of pemphigus vulgaris antigen (desmoglein 3) mediates weak homophilic adhesion. , 1994, The Journal of investigative dermatology.
[54] M. Pasdar,et al. Regulation of desmosome assembly in epithelial cells: kinetics of synthesis, transport, and stabilization of desmoglein I, a major protein of the membrane core domain , 1989, The Journal of cell biology.
[55] B. Gumbiner,et al. The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex , 1988, The Journal of cell biology.
[56] Y. Kitajima,et al. Effects of pemphigus antibody on the regeneration of cell-cell contact in keratinocyte cultures grown in low to normal Ca++ concentration. , 1987, The Journal of investigative dermatology.
[57] F. Watt,et al. Calcium-induced reorganization of desmosomal components in cultured human keratinocytes , 1984, The Journal of cell biology.
[58] Y. Aoyama,et al. Pemphigus vulgaris-IgG causes a rapid depletion of desmoglein 3 (Dsg3) from the Triton X-100 soluble pools, leading to the formation of Dsg3-depleted desmosomes in a human squamous carcinoma cell line, DJM-1 cells. , 1999, The Journal of investigative dermatology.