Suitability of texture features to assess changes in trabecular bone architecture

The purpose of this study was to determine the ability of texture features to assess changes in trabecular bone architecture as projected in radiographs. Micro-CT datasets of trabecular bone were processed to simulate different changes in architecture. Radiographs were simulated by projecting the 3D-bone structure. Texture features, based on mathematical morphology, determined on the simulated radiographs were able to detect structural changes in the trabecular bone.