Fall of blood ionized calcium on watching a provocative TV program and its prevention by active absorbable algal calcium (AAA Ca)

Abstract: In December 1997, more than 680 children developed convulsive seizures while watching a notorious audiovisually provocative TV program, "Pocket Monster." Emotional stimulation via hyperventilation may cause respiratory alkalosis, fall of blood ionized calcium (Ca), and sensitization of the nervous system to excessive emotional stress. A study was therefore undertaken to follow the changes of blood ionized Ca in eight healthy volunteers after watching the "Pocket Monster" and also a quiet program, "Classical Music," as a control for 20 min from 4 p.m. Although neither marked hyperventilation nor convulsions developed in any of these adult volunteers, blood ionized Ca showed a significantly more pronounced fall during and after watching "Pocket Monster," and their plasma intact parathyroid hormone (iPTH) was significantly higher 120 min after the beginning of "Pocket Monster" than the "Classical Music" program. Plasma total Ca, pH, and albumin were free of detectable changes. Ingestion of 600 mg Ca as active absorbable algal Ca (AAA Ca) with high bioavailability completely prevented the fall of ionized Ca and suppressed iPTH. Plama osteocalcin was also significantly suppressed after ingestion of AAA Ca. It may be worthwhile to ingest AAA Ca before anticipated emotional stress such as watching a provocative TV program to prevent possible neuromuscular instability.

[1]  S. Massry,et al.  Calcium metabolism of brain in acute renal failure. Effects of uremia, hemodialysis, and parathyroid hormone. , 1974, The Journal of clinical investigation.

[2]  R. Llinás,et al.  Presynaptic calcium currents and their relation to synaptic transmission: voltage clamp study in squid giant synapse and theoretical model for the calcium gate. , 1976, Proceedings of the National Academy of Sciences of the United States of America.

[3]  S. Kukreja,et al.  Role of adrenergic stimuli in parathyroid hormone secretion in man. , 1975, The Journal of clinical endocrinology and metabolism.

[4]  F. Flach Calcium Metabolism in States of Depression , 1964, British Journal of Psychiatry.

[5]  Y. Fujii,et al.  Overnight Suppression of Parathyroid Hormone and Bone Resorption Markers by Active Absorbable Algae Calcium. A Double-Blind Crossover Study , 1997, Calcified Tissue International.

[6]  A. Hodgkin,et al.  The action of calcium on the electrical properties of squid axons , 1957, The Journal of physiology.

[7]  A. Prasad,et al.  The determination of ultrafiltrable calcium in a variety of clinical conditions. , 1958, The Journal of laboratory and clinical medicine.

[8]  D. Goltzman,et al.  Induction of hypocalcemia by intracerebroventricular injection of calcitonin: evidence for control of blood calcium by the nervous system , 1987, Brain Research.

[9]  M. Blaustein Cellular Calcium: Nervous System , 1988 .

[10]  Carman Js,et al.  Calcium: bivalent cation in the bivalent psychoses. , 1979 .

[11]  R. Wyatt,et al.  Calcium: bivalent cation in the bivalent psychoses. , 1979, Biological psychiatry.

[12]  T. Fujita,et al.  Intestinal absorption of oyster shell electrolysate. , 1988, Bone and mineral.

[13]  B. Frankenhaeuser The effect of calcium on the myelinated nerve fibre , 1957, The Journal of physiology.

[14]  A. Macfie,et al.  Hypocalcaemic myopathy with paranoid psychosis , 1976, Journal of neurology, neurosurgery, and psychiatry.

[15]  S. Massry,et al.  The relationship between the abnormalities in electroencephalogram and blood levels of parathyroid hormone in dialysis patients. , 1980, The Journal of clinical endocrinology and metabolism.

[16]  S. Massry,et al.  Effect of parathyroid hormone and uremia on peripheral nerve calcium and motor nerve conduction velocity. , 1978, The Journal of clinical investigation.

[17]  Prasad As,et al.  The determination of ultrafiltrable calcium in a variety of clinical conditions. , 1958 .