Congenital adrenal cortical hyperplasia--successful long-term treatment.

IT IS ALMOST TWO DECADES since Wilkins and coworkers' first reported the success of cortisor.e treatment of the congenital adrenogenital syndrome with adrenal hyperplasia. Since that time the pathophysiology of this syndrome has been delineated and several variants have been described. The subject was thoroughly reviewed recently by Bongiovanni and Root.2 The number of cases of successful long-term therapy in male children, however, has not been extensive. Experience with such a case, in which the patient was treated with corticosteroids from early childhood for over 15 years, prompts this report.