Radiation‐associated thyroid carcinoma

Since February, 1977, 735 patients having a history of receiving radiation therapy for benign conditions of the head and neck areas during infancy and childhood were examined in a thyroid screening program, and 159 patients were found to have palpable thyroid nodules. These patients had thyroid function tests and indirect laryngoscopy and were followed closely on suppression therapy consisting of either Cytomel or thyroid extract. Thyroidectomy was advised in those in whom the nodules persisted or increased in size. This study documents the incidence of carcinoma and other benign pathological changes and postoperative complications in this group of patients.

[1]  H. Kim,et al.  Radiation-related thyroid carcinoma. , 1978, Archives of surgery.

[2]  L. Ruilope,et al.  INDOMETHACIN AND β-BLOCKERS IN HYPERTENSION , 1978, The Lancet.

[3]  E. Scanlon,et al.  Thyroid disease following irradiation for benign conditions. , 1977, Archives of surgery.

[4]  M E Stachura,et al.  Thyroid cancer occurring as a late consequence of head-and-neck irradiation. Evaluation of 1056 patients. , 1976, The New England journal of medicine.

[5]  V. Marchesi.  Book ReviewPathobiology of Cell Membranes. Vol. 1. , 1976 .

[6]  H. Southwick,et al.  Adult thyroid cancer after head and neck irradiation in infancy and childhood. , 1975, Annals of internal medicine.

[7]  W. Hall,et al.  Neoplasms in persons treated with x-rays in infancy: fourth survey in 20 years. , 1975, Journal of the National Cancer Institute.

[8]  E. Kaplan,et al.  Continuing occurrence of thyroid carcinoma after irradiation to the neck in infancy and childhood. , 1975, The New England journal of medicine.

[9]  J. Sokal,et al.  Suppressive therapy of nontoxic goiter. , 1974, The American journal of medicine.

[10]  B. Modan,et al.  The Lancet: RADIATION-INDUCED HEAD AND NECK TUMOURS , 1974 .

[11]  O. Miettinen,et al.  Neoplasms after childhood irradiation of the thymus gland. , 1971, JAMA.

[12]  C. Key,et al.  Thyroid carcinoma in Hiroshima and Nagasaki. I. Prevalence of thyroid carcinoma at autopsy. , 1969, JAMA.

[13]  L. Hempelmann,et al.  Neoplasms in the Ann Arbor series of thymus-irradiated children; a second survey. , 1968, The American journal of roentgenology, radium therapy, and nuclear medicine.

[14]  T. Sterling,et al.  Neoplasia following therapeutic irradiation for benign conditions in childhood. , 1960, Radiology.

[15]  B. M. Black,et al.  Occult papillary carcinoma of the thyroid gland: a study of 140 cases observed in a 30-year period. , 1960, The Journal of clinical endocrinology and metabolism.

[16]  L. Fuller,et al.  Neoplasia in children treated with X-rays in infancy for thymic enlargement. , 1955, Radiology.

[17]  B. Duffy,et al.  Thyroid cancer in childhood and adolescence. A report on twenty‐eight cases , 1950 .