Analyses of polymorphisms of intron 2 of OPRK1 (kappa-opioid receptor gene) in association with opioid and cocaine dependence diagnoses in an African-American population

[1]  J. Ott,et al.  Genotype Pattern Mining for Pairs of Interacting Variants Underlying Digenic Traits , 2021, Genes.

[2]  L. Farrer,et al.  Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study. , 2020, JAMA psychiatry.

[3]  M. Stallings,et al.  Genetic Architecture and Molecular Neuropathology of Human Cocaine Addiction , 2020, The Journal of Neuroscience.

[4]  M. Stallings,et al.  Cocaine'omics: Genome‐wide and transcriptome‐wide analyses provide biological insight into cocaine use and dependence , 2020, Addiction biology.

[5]  W. Berrettini,et al.  A review of opioid addiction genetics. , 2019, Current opinion in psychology.

[6]  L. Farrer,et al.  Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans , 2018, Biological Psychiatry.

[7]  J. Ott,et al.  Re-evaluation of the KMSK scales, rapid dimensional measures of self-exposure to specific drugs: Gender-specific features. , 2018, Drug and alcohol dependence.

[8]  J. Rotrosen,et al.  A non-coding CRHR2 SNP rs255105, a cis-eQTL for a downstream lincRNA AC005154.6, is associated with heroin addiction , 2018, PloS one.

[9]  E. Butelman,et al.  Gender-specific association of functional prodynorphin 68 bp repeats with cannabis exposure in an African American cohort , 2018, Neuropsychiatric disease and treatment.

[10]  G. Turecki,et al.  Epigenetic regulation of the kappa opioid receptor gene by an insertion–deletion in the promoter region , 2018, European Neuropsychopharmacology.

[11]  D. Goldman,et al.  Severity of alcohol dependence is associated with the fatty acid amide hydrolase Pro129Thr missense variant , 2018, Addiction biology.

[12]  O. Shaul.  How introns enhance gene expression. , 2017, The international journal of biochemistry & cell biology.

[13]  Sajjad Rezaei,et al.  Association of OPRK1 gene polymorphisms with opioid dependence in addicted men undergoing methadone treatment in an Iranian population , 2017, Journal of addictive diseases.

[14]  M. Meaney,et al.  Epigenetic Regulation of the Kappa Opioid Receptor by Child Abuse , 2017, Biological Psychiatry.

[15]  E. Butelman,et al.  “Effects of the novel relatively short-acting kappa opioid receptor antagonist LY2444296 in behaviors observed after chronic extended-access cocaine self-administration in rats” , 2017, Psychopharmacology.

[16]  A. Rose,et al.  The enduring mystery of intron-mediated enhancement. , 2015, Plant science : an international journal of experimental plant biology.

[17]  J. Ott,et al.  Susceptibility loci for heroin and cocaine addiction in the serotonergic and adrenergic pathways in populations of different ancestry. , 2015, Pharmacogenomics.

[18]  Hongyu Zhao,et al.  Genome-Wide Association Study of Opioid Dependence: Multiple Associations Mapped to Calcium and Potassium Pathways , 2014, Biological Psychiatry.

[19]  R. Maldonado,et al.  Effects of Genetic Deletion of Endogenous Opioid System Components on the Reinstatement of Cocaine-Seeking Behavior in Mice , 2014, Neuropsychopharmacology.

[20]  R. Chung,et al.  The Association of Genetic Polymorphisms in the &kgr;-Opioid Receptor 1 Gene With Body Weight, Alcohol Use, and Withdrawal Symptoms in Patients With Methadone Maintenance , 2014, Journal of clinical psychopharmacology.

[21]  G. Uhl,et al.  Implications of genome wide association studies for addiction: are our a priori assumptions all wrong? , 2013, Pharmacology & therapeutics.

[22]  T. Kosten,et al.  The &kgr;-opioid receptor gene as a predictor of response in a cocaine vaccine clinical trial , 2013, Psychiatric genetics.

[23]  A. Doehring,et al.  Genetic-epigenetic interaction modulates μ-opioid receptor regulation. , 2012, Human molecular genetics.

[24]  Shane J. Neph,et al.  Systematic Localization of Common Disease-Associated Variation in Regulatory DNA , 2012, Science.

[25]  O. Levran,et al.  Estimating ancestral proportions in a multi-ethnic US sample: implications for studies of admixed populations , 2012, Human Genomics.

[26]  O. Levran,et al.  The genetics of the opioid system and specific drug addictions , 2012, Human Genetics.

[27]  K. Anastos,et al.  A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women , 2012, Addiction biology.

[28]  G. Bakalkin,et al.  Prodynorphin CpG‐SNPs associated with alcohol dependence: elevated methylation in the brain of human alcoholics , 2011, Addiction biology.

[29]  Leonardo Fazio,et al.  Stress-Related Methylation of the Catechol-O-Methyltransferase Val158 Allele Predicts Human Prefrontal Cognition and Activity , 2011, The Journal of Neuroscience.

[30]  H. Loh,et al.  Transcriptional and epigenetic regulation of opioid receptor genes: present and future. , 2011, Annual review of pharmacology and toxicology.

[31]  Nicole P. Yuan,et al.  Association of substance use disorders with childhood trauma but not African genetic heritage in an African American cohort. , 2009, The American journal of psychiatry.

[32]  D. Epstein.  Cis-regulatory mutations in human disease. , 2009, Briefings in functional genomics & proteomics.

[33]  G. Koob,et al.  Stress, dysregulation of drug reward pathways, and the transition to drug dependence. , 2007, The American journal of psychiatry.

[34]  L. Bierut,et al.  Association of the κ-opioid system with alcohol dependence , 2006, Molecular Psychiatry.

[35]  J. Pintar,et al.  Prior Activation of Kappa Opioid Receptors by U50,488 Mimics Repeated Forced Swim Stress to Potentiate Cocaine Place Preference Conditioning , 2006, Neuropsychopharmacology.

[36]  James L. Howard,et al.  Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats , 2005, Psychopharmacology.

[37]  J. Ott,et al.  Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. , 2004, Pharmacogenetics.

[38]  M. Kreek,et al.  The Kreek-McHugh-Schluger-Kellogg scale: a new, rapid method for quantifying substance abuse and its possible applications. , 2003, Drug and alcohol dependence.

[39]  E. Butelman,et al.  Pharmacotherapy of addictions , 2002, Nature Reviews Drug Discovery.

[40]  J. Woods,et al.  Stimulation of guanosine-5'-o-(3-[35S]thio)triphosphate binding in digitonin-permeabilized C6 rat glioma cells: evidence for an organized association of mu-opioid receptors and G protein. , 2001, The Journal of pharmacology and experimental therapeutics.

[41]  P. Donnelly,et al.  Inference of population structure using multilocus genotype data. , 2000, Genetics.

[42]  M. Kreek,et al.  Acute intermittent morphine increases preprodynorphin and kappa opioid receptor mRNA levels in the rat brain. , 1999, Brain research. Molecular brain research.

[43]  M. Kreek,et al.  'Binge' cocaine administration induces a sustained increase of prodynorphin mRNA in rat caudate-putamen. , 1993, Brain research. Molecular brain research.

[44]  G. Bell,et al.  Cloning and functional comparison of kappa and delta opioid receptors from mouse brain. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[45]  M. Herkenham,et al.  Influence of a single injection of cocaine, amphetamine or GBR 12909 on mRNA expression of striatal neuropeptides. , 1992, Brain research. Molecular brain research.

[46]  G. Koob,et al.  Dynorphin, Dysphoria, and Dependence: the Stress of Addiction , 2016, Neuropsychopharmacology.

[47]  Y. Benjamini,et al.  Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .