Through Upregulation of p21WAF1 Is Not Mediated Through Downregulation of Interleukin-6 Receptors but Growth Inhibition of a Human Myeloma Cell Line by All-transRetinoic Acid

[1]  D. Lavelle,et al.  Inhibition of myeloma cell growth by all-trans retinoic acid is associated with upregulation of p21WAF1 and dephosphorylation of the retinoblastoma protein. , 1999, Leukemia & lymphoma.

[2]  P. L. Bergsagel,et al.  Multiple myeloma: increasing evidence for a multistep transformation process. , 1998, Blood.

[3]  T. Hirano,et al.  Signaling mechanisms through gp130: a model of the cytokine system. , 1997, Cytokine & growth factor reviews.

[4]  M. White,et al.  The IRS-pathway operates distinctively from the Stat-pathway in hematopoietic cells and transduces common and distinct signals during engagement of the insulin or interferon-alpha receptors. , 1997, Blood.

[5]  D. Lavelle,et al.  Modulation of interleukin-6/interleukin-6 receptor cytokine loop in the treatment of multiple myeloma. , 1997, Leukemia & lymphoma.

[6]  K. Anderson,et al.  Interleukin-6 Overcomes p21WAF1 Upregulation and G1 Growth Arrest Induced by Dexamethasone and Interferon-γ in Multiple Myeloma Cells , 1997 .

[7]  D. Levy,et al.  Retinoic acid induces signal transducer and activator of transcription (STAT) 1, STAT2, and p48 expression in myeloid leukemia cells and enhances their responsiveness to interferons. , 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[8]  T. Barbui,et al.  Stat1 is induced and activated by all-trans retinoic acid in acute promyelocytic leukemia cells. , 1997, Blood.

[9]  A. Iavarone,et al.  Transcriptional activation of the human p21(WAF1/CIP1) gene by retinoic acid receptor. Correlation with retinoid induction of U937 cell differentiation. , 1996, The Journal of biological chemistry.

[10]  K. Anderson,et al.  Interleukin-6 promotes multiple myeloma cell growth via phosphorylation of retinoblastoma protein. , 1996, Blood.

[11]  G. Ciliberto,et al.  Interleukin 6 receptor superantagonists are potent inducers of human multiple myeloma cell death. , 1996, Cancer research.

[12]  E. Yang,et al.  Modulation of EGF receptor by tumor necrosis factor-alpha in human hepatocellular carcinoma HepG2 cells. , 1996, Anticancer research.

[13]  E. Borden,et al.  Modulation of Interferon (IFN)-inducible Gene Expression by Retinoic Acid , 1996, The Journal of Biological Chemistry.

[14]  Xin-Yuan Fu,et al.  Cell Growth Arrest and Induction of Cyclin-Dependent Kinase Inhibitor p21WAF1/CIP1 Mediated by STAT1 , 1996, Science.

[15]  M. Colombel,et al.  Retinoic acid modulates the in vivo and in vitro growth of IL‐6 autocrine human myeloma cell lines via induction of apoptosis , 1996, Clinical and experimental immunology.

[16]  Chung Lee,et al.  Modulation of Sensitivity to Transforming Growth Factor-β1 (TGF-β1) and the Level of Type II TGF-β Receptor in LNCaP Cells by Dihydrotestosterone , 1996 .

[17]  P. Desai,et al.  Inhibition of myeloma cell growth by dexamethasone and all-trans retinoic acid: synergy through modulation of interleukin-6 autocrine loop at multiple sites. , 1996, Blood.

[18]  M. White,et al.  Interferon-α Engages the Insulin Receptor Substrate-1 to Associate with the Phosphatidylinositol 3′-Kinase (*) , 1995, The Journal of Biological Chemistry.

[19]  M. Sporn,et al.  Induction of transforming growth factor beta 1 and its receptors during all-trans-retinoic acid (RA) treatment of RA-responsive human neuroblastoma cell lines. , 1995, Cancer research.

[20]  B. Klein,et al.  Interleukin-6 in human multiple myeloma. , 1995, Blood.

[21]  Y. Shima,et al.  Inhibitory effect of all-trans retinoic acid on the growth of freshly isolated myeloma cells via interference with interleukin-6 signal transduction. , 1994, Blood.

[22]  K. Yasukawa,et al.  IL-6-induced homodimerization of gp130 and associated activation of a tyrosine kinase. , 1993, Science.

[23]  M. Baccarini,et al.  IFN-gamma/lipopolysaccharide activation of macrophages is associated with protein kinase C-dependent down-modulation of the colony-stimulating factor-1 receptor. , 1992, Journal of immunology.

[24]  M. Sporn,et al.  Autocrine Secretion—10 Years Later , 1992, Annals of Internal Medicine.

[25]  A. Hasegawa,et al.  Anti‐human interleukin‐6 receptor antibody inhibits human myeloma growth in vivo , 1992, European journal of immunology.

[26]  L. Goldsmith,et al.  Transcriptional control of epidermal growth factor receptor by retinoic acid. , 1992, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[27]  T. Hirano,et al.  Retinoic acid-induced growth inhibition of a human myeloma cell line via down-regulation of IL-6 receptors. , 1991, Journal of immunology.

[28]  S. Jacobsen,et al.  Transforming growth factor-beta trans-modulates the expression of colony stimulating factor receptors on murine hematopoietic progenitor cell lines. , 1991, Blood.

[29]  F. Ruscetti,et al.  Induction of transforming growth factor-beta 1 (TGF-beta 1), receptor expression and TGF-beta 1 protein production in retinoic acid-treated HL-60 cells: possible TGF-beta 1-mediated autocrine inhibition. , 1991, Blood.

[30]  W. Yung,et al.  Inhibition of epidermal growth factor receptor activity by retinoic acid in glioma cells , 1990, Journal of cellular biochemistry.

[31]  H. Asaoku,et al.  Effect of glucocorticoids on the biologic activities of myeloma cells: inhibition of interleukin-1 beta osteoclast activating factor-induced bone resorption. , 1990, Blood.

[32]  H. Balfour,et al.  Human cytomegalovirus infection of kidney glomerular visceral epithelial and tubular epithelial cells in culture. , 1988, Transplantation.

[33]  T. Taniguchi,et al.  Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor. , 1988, Science.

[34]  A. Rizzino Appearance of high affinity receptors for type beta transforming growth factor during differentiation of murine embryonal carcinoma cells. , 1987, Cancer research.

[35]  M. Sporn,et al.  Cellular biology and biochem-istry of the retinoids , 1984 .