Acute Gastroenteritis. The COMMENT Working Group on Acute Diarrhea: Where Are We Now and Where Are We Going?

Recently, the Consensus Group on Outcome Measures Made in Paediatric Enteral Nutrition Clinical Trials (COMMENT) was established. COMMENT agreed that consensus is needed on a core set of outcomes with agreed-upon definitions on what should be measured and reported in nutritional trials. To achieve this goal, 6 working groups were set up, including the working group on Acute Diarrhea. The following 4 steps are needed to complete the work: (1) to identify how outcomes related to acute diarrhea are reported; (2) to decide on the methodology for determining which outcomes to measure in clinical trials; (3) to develop a core outcome set for clinical trials performed in subjects with acute diarrhea; and (4) to determine how to measure the outcomes in the core set. The aim of this paper is to summarize what has been achieved and implemented so far, what is currently being done, and what we aim to achieve in the not so distant future.