Postural orthostatic tachycardia syndrome (POTS): State of the science and clinical care from a 2019 National Institutes of Health Expert Consensus Meeting - Part 1

[1]  A. Diedrich,et al.  Postural orthostatic tachycardia syndrome is associated with significant employment and economic loss , 2021, Journal of internal medicine.

[2]  J. Tyberg,et al.  Compression Garment Reduces Orthostatic Tachycardia and Symptoms in Patients With Postural Orthostatic Tachycardia Syndrome. , 2021, Journal of the American College of Cardiology.

[3]  B. Grubb,et al.  New-onset Postural Orthostatic Tachycardia Syndrome Following Coronavirus Disease 2019 Infection , 2020, The Journal of innovations in cardiac rhythm management.

[4]  S. Jaradeh,et al.  A case report of postural tachycardia syndrome after COVID-19 , 2020, Clinical Autonomic Research.

[5]  M. Persson,et al.  Serum Activity Against G Protein–Coupled Receptors and Severity of Orthostatic Symptoms in Postural Orthostatic Tachycardia Syndrome , 2020, Journal of the American Heart Association.

[6]  A. Diedrich,et al.  Splanchnic Venous Compression Enhances the Effects of ß‐Blockade in the Treatment of Postural Tachycardia Syndrome , 2020, Journal of the American Heart Association.

[7]  L. Weinstock,et al.  Mast Cell Activation Syndrome: A Primer for the Gastroenterologist , 2020, Digestive Diseases and Sciences.

[8]  K. L. Yaxley.  Infectious mononucleosis complicated by peritonsillar abscess and postural orthostatic tachycardia syndrome: A case report , 2020, SAGE open medical case reports.

[9]  S. Raj,et al.  Canadian Cardiovascular Society Position Statement on Postural Orthostatic Tachycardia Syndrome (POTS) and Related Disorders of Chronic Orthostatic Intolerance. , 2020, Canadian Journal of Cardiology.

[10]  T. Bernadzikowski,et al.  Family history of associated disorders in patients with postural tachycardia syndrome , 2020, Cardiology in the Young.

[11]  Amy C. Arnold,et al.  Prevalence of hypermobile Ehlers-Danlos syndrome in postural orthostatic tachycardia syndrome , 2020, Autonomic Neuroscience.

[12]  D. Kem,et al.  Adrenergic Autoantibody‐Induced Postural Tachycardia Syndrome in Rabbits , 2019, Journal of the American Heart Association.

[13]  B. Grubb,et al.  Postural Orthostatic Tachycardia Syndrome Is Associated With Elevated G‐Protein Coupled Receptor Autoantibodies , 2019, Journal of the American Heart Association.

[14]  D. Basso,et al.  AT1AA (Angiotensin II Type-1 Receptor Autoantibodies). , 2019, Hypertension.

[15]  A. Diedrich,et al.  Vagal and Sympathetic Function in Neuropathic Postural Tachycardia Syndrome , 2019, Hypertension.

[16]  A. Diedrich,et al.  The face of postural tachycardia syndrome – insights from a large cross‐sectional online community‐based survey , 2019, Journal of internal medicine.

[17]  K. Chu,et al.  Human leukocyte antigen associations in postural tachycardia syndrome , 2019, Annals of clinical and translational neurology.

[18]  J. Moak,et al.  Utility of Diagnostic Studies for Upper Gastrointestinal Symptoms in Children with Orthostatic Intolerance , 2019, The Journal of pediatrics.

[19]  A. Fedorowski.  Postural orthostatic tachycardia syndrome: clinical presentation, aetiology and management , 2018, Journal of internal medicine.

[20]  J. Schofield,et al.  Intravenous Immunoglobulin Therapy in Refractory Autoimmune Dysautonomias: A Retrospective Analysis of 38 Patients. , 2019, American journal of therapeutics.

[21]  S. Raj,et al.  Moving from the present to the future of Postural Tachycardia Syndrome – What we need , 2018, Autonomic Neuroscience.

[22]  L. Stiles,et al.  Autoimmunity in postural orthostatic tachycardia syndrome: Current understanding , 2018, Autonomic Neuroscience.

[23]  J. R. Boris.  Postural orthostatic tachycardia syndrome in children and adolescents , 2018, Autonomic Neuroscience.

[24]  S. Raj,et al.  Pharmacotherapy for postural tachycardia syndrome , 2018, Autonomic Neuroscience.

[25]  B. Goodman.  Evaluation of postural tachycardia syndrome (POTS) , 2018, Autonomic Neuroscience.

[26]  Amy C. Arnold,et al.  Postural tachycardia syndrome – Diagnosis, physiology, and prognosis , 2018, Autonomic Neuroscience.

[27]  C. Francomano,et al.  Postural tachycardia syndrome and other forms of orthostatic intolerance in Ehlers-Danlos syndrome , 2018, Autonomic Neuroscience.

[28]  Λίλιαν Μάντζιαρη,et al.  2018 ESC Guidelines for the diagnosis and management of syncope. , 2018, Revista espanola de cardiologia.

[29]  J. DiBaise,et al.  Postural Tachycardia Syndrome (POTS) and the GI Tract: A Primer for the Gastroenterologist , 2018, The American Journal of Gastroenterology.

[30]  B. Levine,et al.  Exercise and non-pharmacological treatment of POTS , 2018, Autonomic Neuroscience.

[31]  Hongliang Li,et al.  Angiotensin II Type 1 Receptor Autoantibodies in Postural Tachycardia Syndrome , 2018, Journal of the American Heart Association.

[32]  K. Chu,et al.  Efficacy of Propranolol, Bisoprolol, and Pyridostigmine for Postural Tachycardia Syndrome: a Randomized Clinical Trial , 2018, Neurotherapeutics.

[33]  Y. Ando,et al.  Autoimmune postural orthostatic tachycardia syndrome , 2018, Annals of clinical and translational neurology.

[34]  T. Bernadzikowski,et al.  Demographics of a large paediatric Postural Orthostatic Tachycardia Syndrome Program , 2018, Cardiology in the Young.

[35]  Alicia K. Watkins,et al.  Ivabradine for the Treatment of Postural Orthostatic Tachycardia Syndrome: A Systematic Review , 2018, American Journal of Cardiovascular Drugs.

[36]  L. Weinstock,et al.  Successful treatment of postural orthostatic tachycardia and mast cell activation syndromes using naltrexone, immunoglobulin and antibiotic treatment , 2018, BMJ Case Reports.

[37]  B. Grubb,et al.  The role of autoantibodies in the syndromes of orthostatic intolerance: a systematic review , 2017, Scandinavian cardiovascular journal : SCJ.

[38]  L. Harris,et al.  Spectrum of Autonomic Nervous System Impairment in Sjögren Syndrome , 2017, The neurologist.

[39]  B. Grubb,et al.  Effects of intermittent intravenous saline infusions in patients with medication—refractory postural tachycardia syndrome , 2017, Journal of Interventional Cardiac Electrophysiology.

[40]  O. Melander,et al.  Antiadrenergic autoimmunity in postural tachycardia syndrome , 2016, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[41]  D. Sanders,et al.  Is there a relationship between gluten sensitivity and postural tachycardia syndrome? , 2016, European journal of gastroenterology & hepatology.

[42]  B. Levine,et al.  The international POTS registry: Evaluating the efficacy of an exercise training intervention in a community setting. , 2016, Heart rhythm.

[43]  J. Newton,et al.  A profile of patients with postural tachycardia syndrome and their experience of healthcare in the UK , 2016 .

[44]  Y. Shoenfeld,et al.  Postural Orthostatic Tachycardia Syndrome (POTS) – A novel member of the autoimmune family , 2016, Lupus.

[45]  Jessica R Stumbo,et al.  Syncope in an Athlete: a Case of Infectious Mononucleosis-Induced Postural Tachycardia Syndrome , 2016, Current sports medicine reports.

[46]  Y. Liao,et al.  [Relationship between 24-hour urinary sodium and renin-angiotensin-aldosterone system in children with postural tachycardia syndrome]. , 2015, Zhonghua yi xue za zhi.

[47]  Robert S Sheldon,et al.  2015 heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope. , 2015, Heart rhythm.

[48]  S. Blitshteyn.  Autoimmune markers and autoimmune disorders in patients with postural tachycardia syndrome (POTS) , 2015, Lupus.

[49]  Hongxia Li,et al.  Plasma C-Type Natriuretic Peptide as a Predictor for Therapeutic Response to Metoprolol in Children with Postural Tachycardia Syndrome , 2015, PloS one.

[50]  B. Levine,et al.  Exercise in the postural orthostatic tachycardia syndrome , 2015, Autonomic Neuroscience.

[51]  Junbao Du,et al.  Orthostatic plasma norepinephrine level as a predictor for therapeutic response to metoprolol in children with postural tachycardia syndrome , 2014, Journal of Translational Medicine.

[52]  Chao-shu Tang,et al.  Usefulness of plasma copeptin as a biomarker to predict the therapeutic effectiveness of metoprolol for postural tachycardia syndrome in children. , 2014, The American journal of cardiology.

[53]  B. Goodman.  Immunoresponsive Postinfectious Autonomic Neuropathy , 2014, American journal of therapeutics.

[54]  R. D'Agostino,et al.  Effect of Fludrocortisone Acetate on Chronic Unexplained Nausea and Abdominal Pain in Children With Orthostatic Intolerance , 2014, Journal of pediatric gastroenterology and nutrition.

[55]  Philip L. Mar,et al.  Neuronal and hormonal perturbations in postural tachycardia syndrome , 2014, Front. Physiol..

[56]  J. Newton,et al.  Postural tachycardia syndrome is associated with significant symptoms and functional impairment predominantly affecting young women: a UK perspective , 2014, BMJ Open.

[57]  Hongliang Li,et al.  Autoimmune Basis for Postural Tachycardia Syndrome , 2014, Journal of the American Heart Association.

[58]  Y. Liao,et al.  The Value of Acetylcholine Receptor Antibody in Children with Postural Tachycardia Syndrome , 2014, Pediatric Cardiology.

[59]  W. Dupont,et al.  Effects of Norepinephrine Reuptake Inhibition on Postural Tachycardia Syndrome , 2013, Journal of the American Heart Association.

[60]  W. Shen,et al.  Autoimmunoreactive IgGs against cardiac lipid raft-associated proteins in patients with postural orthostatic tachycardia syndrome. , 2013, Translational research : the journal of laboratory and clinical medicine.

[61]  S. Raj.  Postural Tachycardia Syndrome (POTS) , 2013, Circulation.

[62]  H. Tamai,et al.  GNB3 C825T polymorphism is associated with postural tachycardia syndrome in children , 2012, Pediatrics international : official journal of the Japan Pediatric Society.

[63]  E. Benarroch.  Postural tachycardia syndrome: a heterogeneous and multifactorial disorder. , 2012, Mayo Clinic proceedings.

[64]  J. Stewart,et al.  Mechanisms of sympathetic regulation in orthostatic intolerance. , 2012, Journal of applied physiology.

[65]  Laura M. Padilla‐Walker,et al.  Black hawk down?: Establishing helicopter parenting as a distinct construct from other forms of parental control during emerging adulthood , 2012 .

[66]  W. Dupont,et al.  Desmopressin acutely decreases tachycardia and improves symptoms in the postural tachycardia syndrome. , 2012, Heart rhythm.

[67]  S. Shibata,et al.  Short‐term exercise training improves the cardiovascular response to exercise in the postural orthostatic tachycardia syndrome , 2012, The Journal of physiology.

[68]  Y. Liao,et al.  Midregional pro-adrenomedullin as a predictor for therapeutic response to midodrine hydrochloride in children with postural orthostatic tachycardia syndrome. , 2012, Journal of the American College of Cardiology.

[69]  Kuo-Chin Huang,et al.  Consensus Statement , 2012, Asia-Pacific journal of public health.

[70]  John B. Furness,et al.  The enteric nervous system and neurogastroenterology , 2012, Nature Reviews Gastroenterology &Hepatology.

[71]  W. Dupont,et al.  Altered Systemic Hemodynamic and Baroreflex Response to Angiotensin II in Postural Tachycardia Syndrome , 2012, Circulation. Arrhythmia and electrophysiology.

[72]  A. Diedrich,et al.  Neurohumoral and haemodynamic profile in postural tachycardia and chronic fatigue syndromes , 2011, Clinical science.

[73]  A. Owens,et al.  Postural tachycardia syndrome—current experience and concepts , 2012, Nature Reviews Neurology.

[74]  R. Freeman,et al.  Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome , 2011, Autonomic Neuroscience.

[75]  B. Malow,et al.  Sleep disturbances and diminished quality of life in postural tachycardia syndrome. , 2011, Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine.

[76]  Chao-shu Tang,et al.  Midodrine hydrochloride is effective in the treatment of children with postural orthostatic tachycardia syndrome. , 2011, Circulation journal : official journal of the Japanese Circulation Society.

[77]  W. Dupont,et al.  Abnormalities of angiotensin regulation in postural tachycardia syndrome. , 2011, Heart rhythm.

[78]  O. Fagoaga.  Human Leukocyte Antigen , 2011 .

[79]  S. Seslar.  Cardiac Origins of Postural Orthostatic Tachycardia Syndrome , 2010 .

[80]  B. Levine,et al.  Cardiac origins of the postural orthostatic tachycardia syndrome. , 2010, Journal of the American College of Cardiology.

[81]  Lily Wang,et al.  Distal sudomotor findings in postural tachycardia syndrome , 2010, Clinical Autonomic Research.

[82]  R. Kasmani,et al.  Postural Orthostatic Tachycardia Syndrome Associated With Mycoplasma pneumoniae , 2009 .

[83]  W. Dupont,et al.  Propranolol Decreases Tachycardia and Improves Symptoms in the Postural Tachycardia Syndrome: Less Is More , 2009, Circulation.

[84]  J. Stewart,et al.  Defects in Cutaneous Angiotensin-Converting Enzyme 2 and Angiotensin-(1-7) Production in Postural Tachycardia Syndrome , 2009, Hypertension.

[85]  U. Graham,et al.  Postural orthostatic tachycardia syndrome , 2009, BMJ Case Reports.

[86]  P. Fischer,et al.  Outcomes in Adolescents with Postural Orthostatic Tachycardia Syndrome Treated with Midodrine and β‐Blockers , 2009, Pacing and clinical electrophysiology : PACE.

[87]  W. Shen,et al.  Postural Tachycardia Syndrome (POTS) , 1995, Journal of cardiovascular electrophysiology.

[88]  B. Grubb.  Postural tachycardia syndrome. , 2008, Circulation.

[89]  S. Raj,et al.  The hemodynamic and neurohumoral phenotype of postural tachycardia syndrome , 2007, Neurology.

[90]  S. Raj,et al.  Blood volume perturbations in the postural tachycardia syndrome. , 2007, The American journal of the medical sciences.

[91]  W. Shen,et al.  Postural orthostatic tachycardia syndrome: the Mayo clinic experience. , 2007, Mayo Clinic proceedings.

[92]  Hong-Guang Xie,et al.  β2-Adrenoceptor Genotype and Function Affect Hemodynamic Profile Heterogeneity in Postural Tachycardia Syndrome , 2006 .

[93]  J. Stewart,et al.  Increased plasma angiotensin II in postural tachycardia syndrome (POTS) is related to reduced blood flow and blood volume. , 2006, Clinical science.

[94]  L. Montgomery,et al.  Persistent splanchnic hyperemia during upright tilt in postural tachycardia syndrome. , 2006, American journal of physiology. Heart and circulatory physiology.

[95]  L. D. Montgomery,et al.  Body volume changes during simulated microgravity: Auditory changes, segmental fluid redistribution, and regional hemodynamics , 1993, Annals of Biomedical Engineering.

[96]  Hong-Guang Xie,et al.  Beta2-adrenoceptor genotype and function affect hemodynamic profile heterogeneity in postural tachycardia syndrome. , 2006, Hypertension.

[97]  Scott M. Williams,et al.  Endothelial NO Synthase Polymorphisms and Postural Tachycardia Syndrome , 2005, Hypertension.

[98]  N. Charkoudian,et al.  Baroreflex control of muscle sympathetic nerve activity in postural orthostatic tachycardia syndrome. , 2005, American journal of physiology. Heart and circulatory physiology.

[99]  S. Raj,et al.  Renin-Aldosterone Paradox and Perturbed Blood Volume Regulation Underlying Postural Tachycardia Syndrome , 2005, Circulation.

[100]  S. Sullivan,et al.  Gastrointestinal Symptoms Associated with Orthostatic Intolerance , 2005, Journal of pediatric gastroenterology and nutrition.

[101]  S. Raj,et al.  Hyperadrenergic Postural Tachycardia Syndrome in Mast Cell Activation Disorders , 2005, Hypertension.

[102]  O. Costa,et al.  Clinical improvement in patients with orthostatic intolerance after treatment with bisoprolol and fludrocortisone , 2000, Clinical Autonomic Research.

[103]  R. Freeman,et al.  Sympathetic Nerve Activity in Response to Hypotensive Stress in the Postural Tachycardia Syndrome , 2004, Circulation.

[104]  L. Montgomery,et al.  Regional blood volume and peripheral blood flow in postural tachycardia syndrome. , 2004, American journal of physiology. Heart and circulatory physiology.

[105]  H. Calkins,et al.  Neurally mediated hypotension in systemic lupus erythematosus patients with fibromyalgia. , 2004, Rheumatology.

[106]  J. Stewart,et al.  Reflex vascular defects in the orthostatic tachycardia syndrome of adolescents. , 2001, Journal of applied physiology.

[107]  K. Haruma,et al.  Splanchnic-mesenteric capacitance bed in the postural tachycardia syndrome (POTS) , 2000, Autonomic Neuroscience.

[108]  A. Ertl,et al.  The neuropathic postural tachycardia syndrome. , 2000, The New England journal of medicine.

[109]  J. Stewart.  Autonomic Nervous System Dysfunction in Adolescents with Postural Orthostatic Tachycardia Syndrome and Chronic Fatigue Syndrome Is Characterized by Attenuated Vagal Baroreflex and Potentiated Sympathetic Vasomotion , 2000, Pediatric Research.

[110]  R. Blakely,et al.  Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency. , 2000, The New England journal of medicine.

[111]  S. Sonoda,et al.  Heart rate and plasma cyclic AMP responses to isoproterenol infusion and effect of beta-adrenergic blockade in patients with postural orthostatic tachycardia syndrome. , 2000, Journal of cardiovascular pharmacology.

[112]  P. Sandroni,et al.  Postural tachycardia syndrome: clinical features and follow-up study. , 1999, Mayo Clinic proceedings.

[113]  G. Jacob,et al.  Idiopathic orthostatic intolerance and postural tachycardia syndromes. , 1999, The American journal of the medical sciences.

[114]  D. Kosinski,et al.  The Postural Orthostatic Tachycardia Syndrome: A Neurocardiogenic Variant Identified During Head‐Up Tilt Table Testing , 1997, Pacing and clinical electrophysiology : PACE.

[115]  G. Jacob,et al.  Effects of volume loading and pressor agents in idiopathic orthostatic tachycardia. , 1997, Circulation.

[116]  P. Low,et al.  Idiopathic postural orthostatic tachycardia syndrome , 1993, Neurology.

[117]  F. M. Fouad,et al.  Idiopathic hypovolemia. , 1986, Annals of internal medicine.

[118]  H. Barcroft,et al.  POSTHÆMORRHAGIC FAINTING: STUDY BY CARDIAC OUTPUT AND FOREARM FLOW , 1944 .