An unexpected protective role of low‐affinity allergen‐specific IgG through the inhibitory receptor Fc&ggr;RIIb

[1]  M. Vogel,et al.  A novel bispecific DARPin targeting FcγRIIB and FcεRI‐bound IgE inhibits allergic responses , 2017, Allergy.

[2]  G. Georgiou,et al.  IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions , 2017, Nature Immunology.

[3]  N. Zhong,et al.  The Functional IgE-Blocking Factor Induced by Allergen-Specific Immunotherapy Correlates with IgG4 Antibodies and a Decrease of Symptoms in House Dust Mite-Allergic Children , 2016, International Archives of Allergy and Immunology.

[4]  N. Indrawattana,et al.  A novel IgE-binding epitope of cat major allergen, Fel d 1. , 2016, Biochemical and biophysical research communications.

[5]  E. Enrique,et al.  Immunotherapy (oral and sublingual) for food allergy to fruits. , 2015, The Cochrane database of systematic reviews.

[6]  P. Bruhns,et al.  Mouse and human FcR effector functions , 2015, Immunological reviews.

[7]  M. Jutel,et al.  Allergen Immunotherapy: Past, Present, and Future , 2015, Allergy, asthma & immunology research.

[8]  Ayfer Yukselen,et al.  Role of immunotherapy in the treatment of allergic asthma. , 2014, World journal of clinical cases.

[9]  L. Klimek,et al.  Is The Allergen Really Needed in Allergy Immunotherapy? , 2014, Current Treatment Options in Allergy.

[10]  M. Akdiş New treatments for allergen immunotherapy , 2014, The World Allergy Organization journal.

[11]  T. Kündig,et al.  IgG‐mediated down‐regulation of IgE bound to mast cells: a potential novel mechanism of allergen‐specific desensitization , 2014, Allergy.

[12]  M. Vogel,et al.  Improved FcγRIIb Targeting Functionally Translates into Enhanced Inhibition of Basophil Activation , 2014, International Archives of Allergy and Immunology.

[13]  M. Cragg,et al.  Immunotherapy Targeting Inhibitory Fcγ Receptor IIB (CD32b) in the Mouse Is Limited by Monoclonal Antibody Consumption and Receptor Internalization , 2013, The Journal of Immunology.

[14]  Phillip W Iversen,et al.  Mechanism of Action Assays for Enzymes , 2012 .

[15]  T. Kündig,et al.  Mechanisms of allergen-specific desensitization. , 2010, The Journal of allergy and clinical immunology.

[16]  M. Bachmann,et al.  Isolation of human monoclonal antibodies by mammalian cell display , 2008, Proceedings of the National Academy of Sciences.

[17]  E. Riise,et al.  Several distinct properties of the IgE repertoire determine effector cell degranulation in response to allergen challenge. , 2008, The Journal of allergy and clinical immunology.

[18]  W. Shreffler IgG-Blocking Antibodies Inhibit IgE-Mediated Anaphylaxis in Vivo Through Both Antigen Interception and FcγRIIb Cross-linking , 2007, Pediatrics.

[19]  S. Spector,et al.  Allergen immunotherapy: a practice parameter third update. , 2007, The Journal of allergy and clinical immunology.

[20]  F. Finkelman,et al.  IgG-blocking antibodies inhibit IgE-mediated anaphylaxis in vivo through both antigen interception and FcγRIIb cross-linking , 2006 .

[21]  M. Svenson,et al.  The blocking activity of birch pollen-specific immunotherapy-induced IgG4 is not qualitatively superior to that of other IgG subclasses. , 2004, Molecular immunology.

[22]  J. Cambier,et al.  FcγRIIB activation leads to inhibition of signalling by independently ligated receptors , 2001 .

[23]  J. Oliver,et al.  Negative regulation of FcϵRI signaling by FcγRII costimulation in human blood basophils , 2000 .

[24]  W. Fridman,et al.  Regulation of high-affinity IgE receptor-mediated mast cell activation by murine low-affinity IgG receptors. , 1995, The Journal of clinical investigation.

[25]  J. Dry,et al.  Blocking antibodies to inhalant allergens and asthma. , 1991, Allergie et immunologie.

[26]  K. Roskin,et al.  Single B-cell deconvolution of peanut-specific antibody responses in allergic patients. , 2016, The Journal of allergy and clinical immunology.

[27]  J. Cambier,et al.  Fc gamma RIIB activation leads to inhibition of signalling by independently ligated receptors. , 2003, Biochemical Society transactions.