Increased risk of cardiovascular disease in non-alcoholic fatty liver disease: causal effect or epiphenomenon?

[1]  G. Lippi,et al.  NASH Predicts Plasma Inflammatory Biomarkers Independently of Visceral Fat in Men , 2008, Obesity.

[2]  A. Feldstein,et al.  Increased Hepatic and Circulating Interleukin-6 Levels in Human Nonalcoholic Steatohepatitis , 2008, The American Journal of Gastroenterology.

[3]  B. S. Mohammed,et al.  Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. , 2008, Gastroenterology.

[4]  J. Després,et al.  Visceral obesity and plasma glucose-insulin homeostasis: contributions of interleukin-6 and tumor necrosis factor-alpha in men. , 2008, The Journal of clinical endocrinology and metabolism.

[5]  J. Borén,et al.  Fatty liver, insulin resistance, and dyslipidemia , 2008, Current diabetes reports.

[6]  G. Tell,et al.  Molecular basis and mechanisms of progression of non-alcoholic steatohepatitis. , 2008, Trends in molecular medicine.

[7]  P. Scifo,et al.  Increased mediastinal fat and impaired left ventricular energy metabolism in young men with newly found fatty liver , 2007, Hepatology.

[8]  A. Hakkarainen,et al.  Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects. , 2008 .

[9]  L. N. Valenti,et al.  Carotid artery intima-media thickness in nonalcoholic fatty liver disease. , 2008, The American journal of medicine.

[10]  A. Kotronen,et al.  Tissue specificity of insulin resistance in humans: fat in the liver rather than muscle is associated with features of the metabolic syndrome , 2007, Diabetologia.

[11]  G. Bedogni,et al.  Incidence and natural course of fatty liver in the general population: The Dionysos study , 2007, Hepatology.

[12]  K. Pietiläinen,et al.  Liver fat in the metabolic syndrome. , 2007, The Journal of clinical endocrinology and metabolism.

[13]  M. Abouzari,et al.  Liver: an alarm for the heart? , 2007, Liver international : official journal of the International Association for the Study of the Liver.

[14]  N. Lundbom,et al.  Postprandial lipemia associates with liver fat content. , 2007, The Journal of clinical endocrinology and metabolism.

[15]  A. Häkkinen,et al.  Adipose Tissue Inflammation and Increased Ceramide Content Characterize Subjects With High Liver Fat Content Independent of Obesity , 2007, Diabetes.

[16]  Hirokazu Takahashi,et al.  High-sensitivity C-reactive protein is an independent clinical feature of nonalcoholic steatohepatitis (NASH) and also of the severity of fibrosis in NASH , 2007, Journal of Gastroenterology.

[17]  G. Targher,et al.  Differences and similarities in early atherosclerosis between patients with non-alcoholic steatohepatitis and chronic hepatitis B and C. , 2007, Journal of hepatology.

[18]  Manisha Talim,et al.  Prevalence of Nonalcoholic Fatty Liver Disease and Its Association With Cardiovascular Disease Among Type 2 Diabetic Patients , 2007, Diabetes Care.

[19]  G. Musso,et al.  Polymorphism in microsomal triglyceride transfer protein: A link between liver disease and atherogenic postprandial lipid profile in NASH? , 2007, Hepatology.

[20]  Philipp E. Scherer,et al.  Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans , 2007, Diabetes.

[21]  L. Bouter,et al.  Alanine aminotransferase predicts coronary heart disease events: a 10-year follow-up of the Hoorn Study. , 2007, Atherosclerosis.

[22]  J. Takeda,et al.  Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease. , 2007, World journal of gastroenterology.

[23]  R. D'Agostino,et al.  Gamma Glutamyl Transferase and Metabolic Syndrome, Cardiovascular Disease, and Mortality Risk: The Framingham Heart Study , 2007, Arteriosclerosis, thrombosis, and vascular biology.

[24]  C. Block,et al.  Mechanisms linking obesity with cardiovascular disease , 2006, Nature.

[25]  S. Goland,et al.  Cardiac Abnormalities as a New Manifestation of Nonalcoholic Fatty Liver Disease: Echocardiographic and Tissue Doppler Imaging Assessment , 2006, Journal of clinical gastroenterology.

[26]  M. Holmqvist,et al.  Long‐term follow‐up of patients with NAFLD and elevated liver enzymes , 2006, Hepatology.

[27]  D. Jacobs,et al.  Serum gamma-glutamyltransferase predicts non-fatal myocardial infarction and fatal coronary heart disease among 28,838 middle-aged men and women. , 2006, European heart journal.

[28]  D. Mozaffarian,et al.  Elevated serum alanine aminotransferase activity and calculated risk of coronary heart disease in the United States , 2006, Hepatology.

[29]  T. Lehtimäki,et al.  Liver steatosis coexists with myocardial insulin resistance and coronary dysfunction in patients with type 2 diabetes. , 2006, American journal of physiology. Endocrinology and metabolism.

[30]  H. Ginsberg.  REVIEW: Efficacy and mechanisms of action of statins in the treatment of diabetic dyslipidemia. , 2006, The Journal of clinical endocrinology and metabolism.

[31]  C. Day.  From fat to inflammation. , 2006, Gastroenterology.

[32]  G. Zoppini,et al.  Non-alcoholic fatty liver disease is associated with carotid artery wall thickness in diet-controlled Type 2 diabetic patients , 2006, Journal of endocrinological investigation.

[33]  G. Targher,et al.  Nonalcoholic fatty liver disease and risk of future cardiovascular events among type 2 diabetic patients. , 2005, Diabetes.

[34]  H. Concin,et al.  γ-Glutamyltransferase as a Risk Factor for Cardiovascular Disease Mortality: An Epidemiological Investigation in a Cohort of 163 944 Austrian Adults , 2005, Circulation.

[35]  C. Nievergelt,et al.  Histopathology of pediatric nonalcoholic fatty liver disease , 2005, Hepatology.

[36]  H. Lo,et al.  Sonographic fatty liver, overweight and ischemic heart disease. , 2005, World journal of gastroenterology.

[37]  G. Marchesini,et al.  Endothelial dysfunction and cardiovascular risk profile in nonalcoholic fatty liver disease , 2005, Hepatology.

[38]  S. Sanderson,et al.  The natural history of nonalcoholic fatty liver disease: a population-based cohort study. , 2005, Gastroenterology.

[39]  G. Bedogni,et al.  Prevalence of and risk factors for nonalcoholic fatty liver disease: The Dionysos nutrition and liver study , 2005, Hepatology.

[40]  R. Heine,et al.  Liver alanine aminotransferase, insulin resistance and endothelial dysfunction in normotriglyceridaemic subjects with type 2 diabetes mellitus , 2005, European journal of clinical investigation.

[41]  Emilio Ros,et al.  Nonalcoholic Fatty Liver Disease Is Associated With Carotid Atherosclerosis: A Case–Control Study , 2005, Arteriosclerosis, thrombosis, and vascular biology.

[42]  U. John,et al.  Hepatic steatosis is associated with an increased risk of carotid atherosclerosis. , 2005, World journal of gastroenterology.

[43]  G. Marchesini,et al.  Is liver disease a threat to patients with metabolic disorders? , 2005, Annals of medicine.

[44]  Jonathan C. Cohen,et al.  Prevalence of hepatic steatosis in an urban population in the United States: Impact of ethnicity , 2004, Hepatology.

[45]  C. Ahn,et al.  Metabolic significance of nonalcoholic fatty liver disease in nonobese, nondiabetic adults. , 2004, Archives of internal medicine.

[46]  G. Zoppini,et al.  Relation of nonalcoholic hepatic steatosis to early carotid atherosclerosis in healthy men: role of visceral fat accumulation. , 2004, Diabetes care.

[47]  H. Cortez‐Pinto,et al.  Hepatocyte Apoptosis, Expression of Death Receptors, and Activation of NF-κB in the Liver of Nonalcoholic and Alcoholic Steatohepatitis Patients , 2004, The American Journal of Gastroenterology.

[48]  P Christoffersen,et al.  Long term prognosis of fatty liver: risk of chronic liver disease and death , 2004, Gut.

[49]  S. Kihara,et al.  Adiponectin and Metabolic Syndrome , 2004, Arteriosclerosis, thrombosis, and vascular biology.

[50]  J. Olsen,et al.  Prognosis of patients with a diagnosis of fatty liver--a registry-based cohort study. , 2003, Hepato-gastroenterology.

[51]  Z. Bloomgarden,et al.  Inflammation and insulin resistance. , 2003, Diabetes care.

[52]  G. Marchesini,et al.  Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome , 2003, Hepatology.

[53]  M. Manns,et al.  A comparison of fibrosis progression in chronic liver diseases. , 2003, Journal of hepatology.

[54]  G. Brandi,et al.  Prevalence of and Risk Factors for Hepatic Steatosis in Northern Italy , 2000, Annals of Internal Medicine.

[55]  Z. Younossi,et al.  Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. , 1999, Gastroenterology.

[56]  R. de Marco,et al.  Cause-specific mortality in type 2 diabetes. The Verona Diabetes Study. , 1999, Diabetes care.

[57]  S. Ebrahim,et al.  Gamma-glutamyltransferase: determinants and association with mortality from ischemic heart disease and all causes. , 1995, American journal of epidemiology.

[58]  F. Schaffner,et al.  Nonalcoholic fatty liver disease. , 1986, Progress in liver diseases.