Role of sirtuins in attenuating plaque vulnerability in atherosclerosis

[1]  Yashu Liu,et al.  The sirtuin family in health and disease , 2022, Signal Transduction and Targeted Therapy.

[2]  Steffen E. Petersen,et al.  Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank , 2022, Heart.

[3]  Jie Fang,et al.  Oxidative stress and inflammation regulation of sirtuins: New insights into common oral diseases , 2022, Frontiers in Physiology.

[4]  Yaodong Gu,et al.  The Role of SIRT3 in Exercise and Aging , 2022, Cells.

[5]  D. Agrawal,et al.  LPS and oxLDL-induced S100A12 and RAGE expression in carotid arteries of atherosclerotic Yucatan microswine , 2022, Molecular Biology Reports.

[6]  Demao Zhang,et al.  Mammalian Sirtuins and Their Relevance in Vascular Calcification , 2022, Frontiers in Pharmacology.

[7]  Yalan Wu,et al.  Sirtuin 3 Dependent and Independent Effects of NAD+ to Suppress Vascular Inflammation and Improve Endothelial Function in Mice , 2022, Antioxidants.

[8]  Yunwei Wang,et al.  Regulation of SIRT1 and Its Roles in Inflammation , 2022, Frontiers in Immunology.

[9]  K. Vandenbroeck,et al.  Pathophysiology of Atherosclerosis , 2022, International journal of molecular sciences.

[10]  Pei Jiang,et al.  Association of Sirtuin Gene Polymorphisms with Susceptibility to Coronary Artery Disease in a North Chinese Population , 2022, BioMed research international.

[11]  D. Agrawal,et al.  Heterogeneous Population of Immune cells Associated with Early Thrombosis in Arteriovenous Fistula. , 2022, Journal of surgery and research.

[12]  Qiang Li,et al.  Epigenetic Regulation in Pathology of Atherosclerosis: A Novel Perspective , 2021, Frontiers in Genetics.

[13]  S. Hussein,et al.  Sirtuin-1 in Egyptian patients with coronary artery disease , 2021, Beni-Suef University Journal of Basic and Applied Sciences.

[14]  Hui Zheng,et al.  Role of FoxO transcription factors in aging and age-related metabolic and neurodegenerative diseases , 2021, Cell & Bioscience.

[15]  F. Montecucco,et al.  Sirtuin 1 in Endothelial Dysfunction and Cardiovascular Aging , 2021, Frontiers in Physiology.

[16]  K. Fernando,et al.  Sirtuins as Potential Therapeutic Targets for Mitigating Neuroinflammation Associated With Alzheimer’s Disease , 2021, Frontiers in Cellular Neuroscience.

[17]  E. Bezsonov,et al.  Role of Lipid Accumulation and Inflammation in Atherosclerosis: Focus on Molecular and Cellular Mechanisms , 2021, Frontiers in Cardiovascular Medicine.

[18]  Q. Tu,et al.  DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A2 in human vulnerable atherosclerotic plaque , 2021, Clinical Epigenetics.

[19]  A. Orekhov,et al.  Mitochondrial Dysfunction in Vascular Wall Cells and Its Role in Atherosclerosis , 2021, International journal of molecular sciences.

[20]  Q. Tu,et al.  DNA methylome profiling reveals epigenetic regulation of lipoprotein-associated phospholipase A2 in human vulnerable atherosclerotic plaque , 2021, Clinical Epigenetics.

[21]  Ivan Cancarevic,et al.  A Paradigm Shift in the Management of Atherosclerosis: Protective Role of Sirtuins in Atherosclerosis , 2021, Cureus.

[22]  M. Bennett,et al.  SIRT6 Protects Smooth Muscle Cells From Senescence and Reduces Atherosclerosis , 2020, Circulation research.

[23]  V. Jeney,et al.  Regulation of Vascular Calcification by Reactive Oxygen Species , 2020, Antioxidants.

[24]  F. Jiao,et al.  The Beneficial Roles of SIRT1 in Neuroinflammation-Related Diseases , 2020, Oxidative medicine and cellular longevity.

[25]  R. He,et al.  Mitochondrial Sirtuin 3: New emerging biological function and therapeutic target , 2020, Theranostics.

[26]  W. Shen,et al.  SIRT3 (Sirtuin-3) Prevents Ang II (Angiotensin II)-Induced Macrophage Metabolic Switch Improving Perivascular Adipose Tissue Function. , 2020, Arteriosclerosis, thrombosis, and vascular biology.

[27]  P. K. Sharma,et al.  Atherosclerosis. , 2020, The Journal of the Association of Physicians of India.

[28]  Chao-ran Liu,et al.  Low serum level of sirtuin 1 predicts coronary atherosclerosis plaques during computed tomography angiography among an asymptomatic cohort. , 2019, Coronary artery disease.

[29]  P. Cahill,et al.  Reactive Oxygen Species (ROS), Intimal Thickening, and Subclinical Atherosclerotic Disease , 2019, Front. Cardiovasc. Med..

[30]  A. Hafiane.  Vulnerable Plaque, Characteristics, Detection, and Potential Therapies , 2019, Journal of cardiovascular development and disease.

[31]  F. Cao,et al.  Combating cellular senescence by sirtuins: Implications for atherosclerosis. , 2019, Biochimica et biophysica acta. Molecular basis of disease.

[32]  Ying Jin,et al.  Novel Insights Into the NLRP3 Inflammasome in Atherosclerosis , 2019, Journal of the American Heart Association.

[33]  R. Rahbarghazi,et al.  Role of autophagy in atherosclerosis: foe or friend? , 2019, Journal of Inflammation.

[34]  J. Cooke.  Inflammation and Its Role in Regeneration and Repair. , 2019, Circulation research.

[35]  Kyung‐Jin Min,et al.  Sirtuin signaling in cellular senescence and aging , 2019, BMB reports.

[36]  Shuang Zhou,et al.  Sirtuins and Insulin Resistance , 2018, Front. Endocrinol..

[37]  S. Andrabi,et al.  SIRT3 Regulation Under Cellular Stress: Making Sense of the Ups and Downs , 2018, Front. Neurosci..

[38]  U. Kilic,et al.  High Levels of SIRT1 Expression as a Protective Mechanism Against Disease-Related Conditions , 2018, Front. Endocrinol..

[39]  Jong Seong Roh,et al.  Damage-Associated Molecular Patterns in Inflammatory Diseases , 2018, Immune network.

[40]  Shangha Pan,et al.  PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect , 2018, Cell Death & Disease.

[41]  Huixia Lu,et al.  Contribution of TLR4 signaling in intermittent hypoxia-mediated atherosclerosis progression , 2018, Journal of Translational Medicine.

[42]  Qingbo Xu,et al.  Hypoxia inducible factor as a therapeutic target for atherosclerosis. , 2017, Pharmacology & therapeutics.

[43]  Chu-Han Xiang,et al.  SIRT2 decreases atherosclerotic plaque formation in low-density lipoprotein receptor-deficient mice by modulating macrophage polarization. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[44]  S. Santos,et al.  Nuclear sirtuins and inflammatory signaling pathways. , 2017, Cytokine & growth factor reviews.

[45]  W. Yap,et al.  Oxidative Stress in Cardiovascular Diseases: Involvement of Nrf2 Antioxidant Redox Signaling in Macrophage Foam Cells Formation , 2017, International journal of molecular sciences.

[46]  D. Agrawal,et al.  The role of damage- and pathogen-associated molecular patterns in inflammation-mediated vulnerability of atherosclerotic plaques. , 2017, Canadian journal of physiology and pharmacology.

[47]  Jonathan H. Gillard,et al.  Plaque Rupture in Coronary Atherosclerosis Is Associated With Increased Plaque Structural Stress , 2017, JACC. Cardiovascular imaging.

[48]  C. Stefanadis,et al.  Coronary Atherosclerotic Vulnerable Plaque: Current Perspectives , 2017, Journal of the American Heart Association.

[49]  Md. Shahedur Rahman,et al.  Function of the SIRT3 mitochondrial deacetylase in cellular physiology, cancer, and neurodegenerative disease , 2016, Aging cell.

[50]  P. Quax,et al.  Plaque angiogenesis and its relation to inflammation and atherosclerotic plaque destabilization , 2016, Current opinion in lipidology.

[51]  Suowen Xu,et al.  Sirtuins in Cardiovascular Health and Diseases , 2016, Trends in Endocrinology & Metabolism.

[52]  Zhuoming Li,et al.  Deletion of sirtuin 6 accelerates endothelial dysfunction and atherosclerosis in apolipoprotein E-deficient mice. , 2016, Translational research : the journal of laboratory and clinical medicine.

[53]  D. Agrawal,et al.  Data on TREM-1 activation destabilizing carotid plaques , 2016, Data in brief.

[54]  D. Agrawal,et al.  Dendritic Cells Expressing Triggering Receptor Expressed on Myeloid Cells-1 Correlate with Plaque Stability in Symptomatic and Asymptomatic Patients with Carotid Stenosis , 2016, PloS one.

[55]  D. Agrawal,et al.  Tumor necrosis factor-α regulates triggering receptor expressed on myeloid cells-1-dependent matrix metalloproteinases in the carotid plaques of symptomatic patients with carotid stenosis. , 2016, Atherosclerosis.

[56]  P. Little,et al.  SIRT6 protects against endothelial dysfunction and atherosclerosis in mice , 2016, Aging.

[57]  B. Lacey,et al.  Epidemiology of Atherosclerosis and the Potential to Reduce the Global Burden of Atherothrombotic Disease. , 2016, Circulation research.

[58]  C. McCall,et al.  Sirtuins Link Inflammation and Metabolism , 2016, Journal of immunology research.

[59]  M. Russo,et al.  The Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and Progression , 2015, Oxidative medicine and cellular longevity.

[60]  S. Leung.  The Role of Sirtuin 6 in Maintaining Vascular Integrity , 2016 .

[61]  P. Libby,et al.  Inflammation and plaque vulnerability , 2015, Journal of internal medicine.

[62]  P. Conti,et al.  Atherosclerosis: a chronic inflammatory disease mediated by mast cells , 2015, Central-European journal of immunology.

[63]  L. Guarente,et al.  The multifaceted functions of sirtuins in cancer , 2015, Nature Reviews Cancer.

[64]  Zhuo Zhang,et al.  Arsenic Induces Insulin Resistance in Mouse Adipocytes and Myotubes Via Oxidative Stress-Regulated Mitochondrial Sirt3-FOXO3a Signaling Pathway. , 2015, Toxicological sciences : an official journal of the Society of Toxicology.

[65]  B. Morris,et al.  FOXO3: A Major Gene for Human Longevity - A Mini-Review , 2015, Gerontology.

[66]  I. Perrotta,et al.  The Role of Oxidative Stress and Autophagy in Atherosclerosis , 2015, Oxidative medicine and cellular longevity.

[67]  V. Dolinsky,et al.  Sirtuin-3 (SIRT3) Protein Attenuates Doxorubicin-induced Oxidative Stress and Improves Mitochondrial Respiration in H9c2 Cardiomyocytes* , 2015, The Journal of Biological Chemistry.

[68]  Hening Lin,et al.  Sirtuins in Epigenetic Regulation , 2015, Chemical reviews.

[69]  Danny L Wang,et al.  SIRT3 interactions with FOXO3 acetylation, phosphorylation and ubiquitinylation mediate endothelial cell responses to hypoxia. , 2014, The Biochemical journal.

[70]  J. Auwerx,et al.  A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function. , 2014, Cell metabolism.

[71]  G. Paolisso,et al.  Sirtuin 6 Expression and Inflammatory Activity in Diabetic Atherosclerotic Plaques: Effects of Incretin Treatment , 2014, Diabetes.

[72]  P. Tchounwou,et al.  The Renin-Angiotensin-Aldosterone System in Vascular Inflammation and Remodeling , 2014, International journal of inflammation.

[73]  W. Kong,et al.  Age-Related Decrease in the Mitochondrial Sirtuin Deacetylase Sirt3 Expression Associated with ROS Accumulation in the Auditory Cortex of the Mimetic Aging Rat Model , 2014, PloS one.

[74]  E. Falk,et al.  Mechanisms of Plaque Formation and Rupture , 2014 .

[75]  T. Suuronen,et al.  Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders. , 2013, Cellular signalling.

[76]  A. Utsunomiya,et al.  Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy. , 2013, Brain : a journal of neurology.

[77]  Alan D. Lopez,et al.  Measuring the global burden of disease. , 2013, The New England journal of medicine.

[78]  C. Monaco,et al.  Biomechanical factors and macrophages in plaque stability. , 2013, Cardiovascular research.

[79]  C. Monaco,et al.  Toll-Like Receptors in Atherosclerosis , 2013, International journal of molecular sciences.

[80]  M. Bennett,et al.  Vascular Smooth Muscle Cell Sirtuin 1 Protects Against DNA Damage and Inhibits Atherosclerosis , 2013, Circulation.

[81]  J. Mehta,et al.  Oxidant stress in mitochondrial DNA damage, autophagy and inflammation in atherosclerosis , 2013, Scientific Reports.

[82]  M. Oellerich,et al.  FOXOs and Sirtuins in Vascular Growth, Maintenance, and Aging , 2012, Circulation research.

[83]  M. Tschan,et al.  Inhibition of SIRT1 Impairs the Accumulation and Transcriptional Activity of HIF-1α Protein under Hypoxic Conditions , 2012, PloS one.

[84]  E. Verdin,et al.  SIRT3 and cancer: tumor promoter or suppressor? , 2011, Biochimica et biophysica acta.

[85]  Eun Jin Lee,et al.  Tumor necrosis factor α-mediated cleavage and inactivation of SirT1 in human osteoarthritic chondrocytes. , 2011, Arthritis and rheumatism.

[86]  P. Pandolfi,et al.  SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization. , 2011, Cancer cell.

[87]  R. Chen,et al.  Hypoxia Increases Sirtuin 1 Expression in a Hypoxia-inducible Factor-dependent Manner* , 2011, The Journal of Biological Chemistry.

[88]  Wei Yu,et al.  Sirt3 Mediates Reduction of Oxidative Damage and Prevention of Age-Related Hearing Loss under Caloric Restriction , 2010, Cell.

[89]  G. Remuzzi,et al.  Angiotensin II revisited: new roles in inflammation, immunology and aging , 2010, EMBO molecular medicine.

[90]  R. Virmani,et al.  Concept of vulnerable/unstable plaque. , 2010, Arteriosclerosis, thrombosis, and vascular biology.

[91]  Junjie Chen,et al.  Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxia-inducible factor 1alpha. , 2010, Molecular cell.

[92]  L. Polito,et al.  The molecular genetics of sirtuins: association with human longevity and age-related diseases. , 2010, International journal of molecular epidemiology and genetics.

[93]  Yu Wang,et al.  SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aortic Endothelial Cells , 2010, Circulation research.

[94]  C. Deng,et al.  SIRT3 is a mitochondria-localized tumor suppressor required for maintenance of mitochondrial integrity and metabolism during stress. , 2010, Cancer cell.

[95]  Gene Kim,et al.  Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. , 2009, The Journal of clinical investigation.

[96]  Erling Falk,et al.  Pathogenesis of atherosclerosis. , 2006, Journal of the American College of Cardiology.

[97]  S. Nemoto,et al.  Nutrient Availability Regulates SIRT1 Through a Forkhead-Dependent Pathway , 2004, Science.

[98]  P. Libby.  Inflammation in atherosclerosis , 2002, Nature.

[99]  L. Arroyo,et al.  Mechanisms of plaque rupture: mechanical and biologic interactions. , 1999, Cardiovascular research.

[100]  N. Iwai,et al.  Induction of renin in medial smooth muscle cells by balloon injury. , 1997, Hypertension.