The Effect of Statins on Blood Gene Expression in COPD
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M. Obeidat | Y. Bossé | P. Paré | B. McManus | R. Ng | D. Sin | B. Miller | S. Rennard | N. Fishbane | S. Tebbutt | Z. Hollander | V. Chen | Yunlong Nie | P. Paré
[1] N. Horita,et al. Statins reduce all-cause mortality in chronic obstructive pulmonary disease: a systematic review and meta-analysis of observational studies , 2014, Respiratory Research.
[2] J. Auwerx,et al. A method to identify and validate mitochondrial modulators using mammalian cells and the worm C. elegans , 2014, Scientific Reports.
[3] Meilan K. Han,et al. Simvastatin for the prevention of exacerbations in moderate-to-severe COPD. , 2014, The New England journal of medicine.
[4] A. Zeki. Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy , 2014, European Respiratory Journal.
[5] T. Steele,et al. Statins inhibit proliferation and cytotoxicity of a human leukemic natural killer cell line , 2013, Biomarker Research.
[6] Fuqiang Wen,et al. Increased Serum ox-LDL Levels Correlated with Lung Function, Inflammation, and Oxidative Stress in COPD , 2013, Mediators of inflammation.
[7] K. Gowdy,et al. Emerging roles for cholesterol and lipoproteins in lung disease. , 2013, Pulmonary pharmacology & therapeutics.
[8] M. Tobin,et al. APOM and high-density lipoprotein cholesterol are associated with lung function and per cent emphysema , 2013, European Respiratory Journal.
[9] Anil Kumar,et al. Synergistical neuroprotection of rofecoxib and statins against malonic acid induced Huntington's disease like symptoms and related cognitive dysfunction in rats. , 2013, European journal of pharmacology.
[10] Bin Chen,et al. Relating genes to function: identifying enriched transcription factors using the ENCODE ChIP-Seq significance tool , 2013, Bioinform..
[11] Jing Wang,et al. WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013 , 2013, Nucleic Acids Res..
[12] J. Kastelein,et al. Identification of a loss-of-function inducible degrader of the low-density lipoprotein receptor variant in individuals with low circulating low-density lipoprotein. , 2013, European heart journal.
[13] M. Decramer,et al. Chronic obstructive pulmonary disease and comorbidities. , 2013, The Lancet. Respiratory medicine.
[14] K. Pinkerton,et al. Simvastatin inhibits smoke-induced airway epithelial injury: implications for COPD therapy , 2012, European Respiratory Journal.
[15] A. Zarbock,et al. CXCR2: From Bench to Bedside , 2012, Front. Immun..
[16] J. D’Armiento,et al. Activation of the TLR4 signaling pathway and abnormal cholesterol efflux lead to emphysema in ApoE-deficient mice. , 2012, American journal of physiology. Lung cellular and molecular physiology.
[17] K. Azzam,et al. Crosstalk between reverse cholesterol transport and innate immunity , 2012, Trends in Endocrinology & Metabolism.
[18] F. Bushman,et al. Cxcr2 and Cxcl5 regulate the IL-17/G-CSF axis and neutrophil homeostasis in mice. , 2012, The Journal of clinical investigation.
[19] Andrew E. Jaffe,et al. Bioinformatics Applications Note Gene Expression the Sva Package for Removing Batch Effects and Other Unwanted Variation in High-throughput Experiments , 2022 .
[20] J. Burgos,et al. Simvastatin modulates the Alzheimer's disease-related gene seladin-1. , 2012, Journal of Alzheimer's disease : JAD.
[21] Jesse M. Engreitz,et al. ProfileChaser: searching microarray repositories based on genome-wide patterns of differential expression , 2011, Bioinform..
[22] R. Kozlov,et al. Serotypes of Streptococcus Pneumoniae in Children of Russian Federation , 2011, Pediatric Research.
[23] D. Massaro,et al. Developmental Alveologenesis: New Roles for ApoE and LDL Receptor , 2011, Pediatric Research.
[24] Steven R. Jones,et al. Advanced chronic obstructive pulmonary disease is associated with high levels of high-density lipoprotein cholesterol. , 2011, The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.
[25] P. Austin. An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational Studies , 2011, Multivariate behavioral research.
[26] C. Culmsee,et al. Statins — increasing or reducing the risk of Parkinson's disease? , 2011, Experimental Neurology.
[27] K. Pahan,et al. Prospects of Statins in Parkinson Disease , 2011, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[28] J. Maurer. Dynamic Hyperinflation During Daily Activities: Does COPD Global Initiative for Chronic Obstructive Lung Disease Stage Matter? , 2011 .
[29] D. Sin,et al. Statin reverses smoke-induced pulmonary hypertension and prevents emphysema but not airway remodeling. , 2011, American journal of respiratory and critical care medicine.
[30] R. Curi,et al. ABCA1 and ABCG1 expressions are regulated by statins and ezetimibe in Caco-2 cells , 2011, Drug metabolism and drug interactions.
[31] G. Hoser,et al. Different statins produce highly divergent changes in gene expression profiles of human hepatoma cells: a pilot study. , 2011, Acta biochimica Polonica.
[32] Rafael A. Irizarry,et al. A framework for oligonucleotide microarray preprocessing , 2010, Bioinform..
[33] A. Remaley,et al. ATP-binding cassette transporter G1 deficiency dysregulates host defense in the lung. , 2010, American journal of respiratory and critical care medicine.
[34] D. Link,et al. CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow. , 2010, The Journal of clinical investigation.
[35] A. Tall,et al. Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses. , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[36] R. Hopkins,et al. Pharmacological actions of statins: potential utility in COPD , 2009, European Respiratory Review.
[37] M. Etminan,et al. Statins in COPD: a systematic review. , 2009, Chest.
[38] G. Marks,et al. Associations between statins and COPD: a systematic review , 2009, BMC pulmonary medicine.
[39] P. Barter,et al. Role of 3&bgr;-Hydroxysteroid-&Dgr;24 Reductase in Mediating Antiinflammatory Effects of High-Density Lipoproteins in Endothelial Cells , 2009, Arteriosclerosis, thrombosis, and vascular biology.
[40] F. V. Álvarez,et al. Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) , 2009 .
[41] S. Hazen,et al. Role of HDL , ABCA 1 , and ABCG 1 Transporters in Cholesterol Efflux and Immune Responses , 2009 .
[42] V. Debari,et al. Statins may reduce episodes of exacerbation and the requirement for intubation in patients with COPD: evidence from a retrospective cohort study , 2008, International journal of clinical practice.
[43] W. MacNee,et al. Evaluation of COPD Longitudinally to Identify Predictive Surrogate End-points (ECLIPSE) , 2008, European Respiratory Journal.
[44] C. Hedrick,et al. A Critical Role for ABCG1 in Macrophage Inflammation and Lung Homeostasis1 , 2008, The Journal of Immunology.
[45] P. Ping,et al. Loss of ABCG1 Results in Chronic Pulmonary Inflammation1 , 2008, The Journal of Immunology.
[46] P. Vokonas,et al. Statin use reduces decline in lung function: VA Normative Aging Study. , 2007, American journal of respiratory and critical care medicine.
[47] John D. Storey,et al. Capturing Heterogeneity in Gene Expression Studies by Surrogate Variable Analysis , 2007, PLoS genetics.
[48] B. Skipper,et al. Influenza and COPD mortality protection as pleiotropic, dose-dependent effects of statins. , 2007, Chest.
[49] J. Growdon,et al. Molecular markers of early Parkinson's disease based on gene expression in blood , 2007, Proceedings of the National Academy of Sciences.
[50] Robert Gentleman,et al. Using GOstats to test gene lists for GO term association , 2007, Bioinform..
[51] Andrew J. Brown,et al. SREBP-2 positively regulates transcription of the cholesterol efflux gene, ABCA1, by generating oxysterol ligands for LXR. , 2006, The Biochemical journal.
[52] Klaus Obermayer,et al. A new summarization method for affymetrix probe level data , 2006, Bioinform..
[53] W. Longmore,et al. Regulation of lung surfactant cholesterol metabolism by serum lipoproteins , 1980, Lipids.
[54] O. Francone,et al. Pulmonary abnormalities due to ABCA1 deficiency in mice. , 2005, American journal of physiology. Lung cellular and molecular physiology.
[55] R V Jensen,et al. Genome-wide expression profiling of human blood reveals biomarkers for Huntington's disease. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[56] F. Mach,et al. Statins Reduce Interleukin-6–Induced C-Reactive Protein in Human Hepatocytes: New Evidence for Direct Antiinflammatory Effects of Statins , 2005, Arteriosclerosis, thrombosis, and vascular biology.
[57] Gordon K Smyth,et al. Statistical Applications in Genetics and Molecular Biology Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments , 2011 .
[58] Susumu Goto,et al. The KEGG resource for deciphering the genome , 2004, Nucleic Acids Res..
[59] R. Atmar,et al. Biopsy neutrophilia, neutrophil chemokine and receptor gene expression in severe exacerbations of chronic obstructive pulmonary disease. , 2003, American journal of respiratory and critical care medicine.
[60] Rafael A Irizarry,et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. , 2003, Biostatistics.
[61] R. Perez,et al. Ubiquinone does not rescue acute myeloid leukemia cells from growth inhibition by statins , 2003, Leukemia.
[62] Y. Friedlander,et al. Sterol-regulatory element-binding protein (SREBP)-2 contributes to polygenic hypercholesterolaemia. , 2002, Atherosclerosis.
[63] AndrewJ. S. Coats. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial , 2002, The Lancet.
[64] W. Bailey,et al. Editorial: Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Guidelines for COPD, Including COVID-19, Climate Change, and Air Pollution , 2023, Medical science monitor : international medical journal of experimental and clinical research.
[65] P. Cassano,et al. Lipids and pulmonary function in the Third National Health and Nutrition Examination Survey. , 2002, American journal of epidemiology.
[66] S. Yusuf. MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20536 high-risk individuals: a randomised placebo-controlled trial. Commentary , 2002 .
[67] R. Evans,et al. Nuclear receptors and lipid physiology: opening the X-files. , 2001, Science.
[68] C. Stancu,et al. Statins: mechanism of action and effects , 2001, Journal of cellular and molecular medicine.
[69] R. Hohl,et al. Interaction of cytosine arabinoside and lovastatin in human leukemia cells. , 2001, Leukemia research.
[70] M. Ashburner,et al. Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.
[71] Alan D. Lopez,et al. Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study , 1997, The Lancet.
[72] Y. Benjamini,et al. Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .
[73] M. Simionescu,et al. Uptake of low density lipoproteins by the hamster lung. Interactions with capillary endothelium. , 1986, The American review of respiratory disease.
[74] S. Grundy,et al. Increased high density lipoprotein cholesterol in obstructive pulmonary disease (predominant emphysematous type). , 1981, Metabolism: clinical and experimental.