Localized removal of layers of metal, polymer, or biomaterial by ultrasound cavitation bubbles.

We present an ultrasonic device with the ability to locally remove deposited layers from a glass slide in a controlled and rapid manner. The cleaning takes place as the result of cavitating bubbles near the deposited layers and not due to acoustic streaming. The bubbles are ejected from air-filled cavities micromachined in a silicon surface, which, when vibrated ultrasonically at a frequency of 200 kHz, generate a stream of bubbles that travel to the layer deposited on an opposing glass slide. Depending on the pressure amplitude, the bubble clouds ejected from the micropits attain different shapes as a result of complex bubble interaction forces, leading to distinct shapes of the cleaned areas. We have determined the removal rates for several inorganic and organic materials and obtained an improved efficiency in cleaning when compared to conventional cleaning equipment. We also provide values of the force the bubbles are able to exert on an atomic force microscope tip.

[1]  D. Lohse,et al.  Taming acoustic cavitation , 2012, 1210.4016.

[2]  D. Lohse,et al.  Sonoluminescence and sonochemiluminescence from a microreactor. , 2012, Ultrasonics sonochemistry.

[3]  G. Cravotto,et al.  Harnessing mechanochemical effects with ultrasound-induced reactions , 2012 .

[4]  A. Zijlstra Acoustic Surface Cavitation , 2011 .

[5]  S. Curteanu,et al.  Covalent and ionic co-cross-linking--an original way to prepare chitosan-gelatin hydrogels for biomedical applications. , 2011, Journal of biomedical materials research. Part A.

[6]  M. Goosey,et al.  Initial studies into the use of ultrasound to reduce process temperatures and chemical usage in the PCB desmear process , 2011 .

[7]  D. Lohse,et al.  Efficient sonochemistry through microbubbles generated with micromachined surfaces. , 2010, Angewandte Chemie.

[8]  K. Suslick,et al.  Applications of Ultrasound to the Synthesis of Nanostructured Materials , 2010, Advanced materials.

[9]  B C Khoo,et al.  The dynamics of a non-equilibrium bubble near bio-materials , 2009, Physics in medicine and biology.

[10]  S. Bayoudh,et al.  Assessing bacterial adhesion using DLVO and XDLVO theories and the jet impingement technique. , 2009, Colloids and surfaces. B, Biointerfaces.

[11]  D. Lohse,et al.  Nucleation threshold and deactivation mechanisms of nanoscopic cavitation nuclei , 2009, 0906.0556.

[12]  Raffi Karshafian,et al.  Sonoporation by ultrasound-activated microbubble contrast agents: effect of acoustic exposure parameters on cell membrane permeability and cell viability. , 2009, Ultrasound in medicine & biology.

[13]  J. Dutcher,et al.  Absolute quantitation of bacterial biofilm adhesion and viscoelasticity by microbead force spectroscopy. , 2009, Biophysical journal.

[14]  Leslie Y Yeo,et al.  Ultrafast microfluidics using surface acoustic waves. , 2009, Biomicrofluidics.

[15]  A. van den Berg,et al.  Controlled cavitation–cell interaction: trans-membrane transport and viability studies , 2008, Physics in medicine and biology.

[16]  Hans-Curt Flemming,et al.  The EPS Matrix: The “House of Biofilm Cells” , 2007, Journal of bacteriology.

[17]  D. Lohse,et al.  Effect of nuclei concentration on cavitation cluster dynamics. , 2007, The Journal of the Acoustical Society of America.

[18]  W. Coakley,et al.  Applications of ultrasound streaming and radiation force in biosensors. , 2007, Biosensors & bioelectronics.

[19]  Nico de Jong,et al.  Sonoporation from jetting cavitation bubbles. , 2006, Biophysical journal.

[20]  Claus-Dieter Ohl,et al.  Controlled multibubble surface cavitation. , 2006, Physical review letters.

[21]  D. Ørstavik,et al.  The susceptibility of starved, stationary phase, and growing cells of Enterococcus faecalis to endodontic medicaments. , 2005, Journal of endodontics.

[22]  Detlef Lohse,et al.  Sonoluminescence: Cavitation hots up , 2005, Nature.

[23]  Parag R Gogate,et al.  Sonochemical reactors: scale up aspects. , 2004, Ultrasonics sonochemistry.

[24]  C. Ohl,et al.  Detachment and sonoporation of adherent HeLa-cells by shock wave-induced cavitation. , 2003, Biochimica et biophysica acta.

[25]  P. Marmottant,et al.  Controlled vesicle deformation and lysis by single oscillating bubbles , 2003, Nature.

[26]  K. Suslick,et al.  The energy efficiency of formation of photons, radicals and ions during single-bubble cavitation , 2002, Nature.

[27]  Detlef Lohse,et al.  Single bubble sonoluminescence , 2002 .

[28]  W. Dunne,et al.  Bacterial Adhesion: Seen Any Good Biofilms Lately? , 2002, Clinical Microbiology Reviews.

[29]  M. Heyns,et al.  Removal of Submicrometer Particles from Silicon Wafer Surfaces Using HF-Based Cleaning Mixtures , 2001 .

[30]  J J Heijnen,et al.  Two-dimensional model of biofilm detachment caused by internal stress from liquid flow. , 2001, Biotechnology and bioengineering.

[31]  S. Wereley,et al.  Volume illumination for two-dimensional particle image velocimetry , 2000 .

[32]  Yuehuei H. An,et al.  Handbook of Bacterial Adhesion , 2000, Humana Press.

[33]  Z Lewandowski,et al.  Structural deformation of bacterial biofilms caused by short-term fluctuations in fluid shear: an in situ investigation of biofilm rheology. , 1999, Biotechnology and bioengineering.

[34]  C. Kirschner,et al.  The role of intermolecular interactions: studies on model systems for bacterial biofilms. , 1999, International journal of biological macromolecules.

[35]  M. Sharma,et al.  Effect of Surface Hydrophobicity on the Hydrodynamic Detachment of Particles from Surfaces , 1999 .

[36]  Olgert Lindau,et al.  Bubble dynamics, shock waves and sonoluminescence , 1999, Philosophical Transactions of the Royal Society of London. Series A: Mathematical, Physical and Engineering Sciences.

[37]  J. Feder,et al.  Characteristic protein adhesion forces on glass and polystyrene substrates by atomic force microscopy , 1998 .

[38]  Yoon,et al.  Hydrophobic Interactions between Dissimilar Surfaces , 1997, Journal of colloid and interface science.

[39]  T. Okada Relation between impact load and the damage produced by cavitation bubble collapse , 1995 .

[40]  P. Riesz,et al.  Free radical formation induced by ultrasound and its biological implications. , 1992, Free radical biology & medicine.

[41]  K. Suslick Sonochemistry , 1990, Science.

[42]  D. Riemer High-Adhesion Thick-Film Gold Without Glass or Metal-Oxide Powder Additives , 1985 .

[43]  J. Israelachvili,et al.  Measurement of the hydrophobic interaction between two hydrophobic surfaces in aqueous electrolyte solutions , 1984 .

[44]  S. Seltzer,et al.  Endodontic failures--an analysis based on clinical, roentgenographic, and histologic findings. II. , 1967, Oral surgery, oral medicine, and oral pathology.

[45]  P. Benjamin,et al.  Adhesion of metal films to glass , 1960, Proceedings of the Royal Society of London. Series A. Mathematical and Physical Sciences.

[46]  D. Lohse,et al.  Ultrasound artificially nucleated bubbles and their sonochemical radical production. , 2013, Ultrasonics sonochemistry.

[47]  J. Graves,et al.  New evidence for the inverse dependence of mechanical and chemical effects on the frequency of ultrasound. , 2011, Ultrasonics sonochemistry.

[48]  W. Nyborg,et al.  Current status of research on biophysical effects of ultrasound. , 1994, Ultrasound in medicine & biology.

[49]  J. Minford Durability Evaluation of Adhesive Bonded Structures , 1991 .

[50]  Jl Vossen,et al.  Measurements of Film-Substrate Bond Strength by Laser Spallation , 1978 .

[51]  Kl Mittal,et al.  Adhesion measurement: Recent progress, unsolved problems, and prospects , 1978 .