HYPOXANTHINE COMPLEXES WITH FIRST ROW TRANSITION METAL PERCHLORATES

Abstract Complexes of hypoxanthine (hxH) with 3d metal perchlorates were synthesized by refluxing mixtures of ligand and metal salt in ethyl acetate-triethyl orthoformate. In all cases investigated, partial substitution of one anionic hx″ for one C104 group occurred. The solid complexes isolated contain also two or three neutral hxH ligands per metal ion, vizM(hx)(hxH)3 (C104)2 (M = Cr, Fe), M(hx)(hxH)3 C104 H2 0 (M = Mn, Cu, Zn), Co(hx)(hxH)3 C104 and M(hx)(hxH)2 C104 H2 0 (M = Fe, Ni). The new complexes appear to be generally polymeric species characterized by a single-bridged -M-hx-J-, backbone, in which bidentate hx' probably binds viaN3 and N7 to adjacent metal ions. The neutral hxH ligands are terminal N7-bound. The Co(II) complex is pentacoordinated with three terminal hxH ligands and ionic C104. The rest of the complexes are hexacoordinated, containing two or three terminal hxH ligands and the following additional ligands; M = Fe2 +, Ni2+ : -OC103, aqua; M = Cr3 +, Fe3+ : -OC103 (also ionic C104);...

[1]  N. Karayannis,et al.  ADDUCTS OF THEOBROMINE WITH 3d METAL PERCHLORATES , 1988 .

[2]  S. Grossman,et al.  Zirconium(IV) oxochloride complexes with xanthines and hypoxanthine , 1987 .

[3]  W. Bensch,et al.  Coordination properties of hypoxanthine: Crystal structures, thermal analysis, IR, and electronic spectral studies of CU(II)(hypoxanthine) SO4·H2O and of ME(II)(hypoxanthine)SO4·5H2O (Me(II) CO(II), Ni(II)) , 1987 .

[4]  S. Grossman,et al.  Hypoxanthine, xanthine and theobromine complexes with palladium(II) and platinum(IV) chlorides , 1987 .

[5]  S. Grossman,et al.  THEOPHYLLINE ADDUCTS WITH 3d METAL PERCHLORATES , 1987 .

[6]  G. Jameson,et al.  Uric acid salts of magnesium: crystal and molecular structures and thermal analysis of two phases of Mg(C5H3N4O3)2•8H2O , 1986 .

[7]  W. Sheldrick,et al.  Characterisation of Metal Binding Sites for 8-Azaguanine and 8-Azahypoxanthine Derivatives Synthesis and X-Ray Structural Analysis of Methylmercury(II) and Zinc(II) Complexes , 1986 .

[8]  N. Karayannis,et al.  Facilitation of the syntheses of metal perchlorate complexes with purines from non-aqueous suspensions by substituting ethyl acetate for ethanol in the interaction medium , 1985 .

[9]  A. Beauchamp,et al.  Reactions of the methylmercury cation with xanthine and crystal structures of μ-(xanthinato-N3,N7,N9)tris(methylmercury(II)) nitrate and μ-(xanthinato-N1,N3,N7,N9)tetrakis(methylmercury(II)) nitrate , 1984 .

[10]  T. Theophanides,et al.  An FT-ir study of cis- and trans-dichlorodiammineplatinum(II) bound to inosine-5'-monophosphate , 1984 .

[11]  N. Karayannis,et al.  Guanine complexes with first row transition metal perchlorates , 1983 .

[12]  N. Karayannis,et al.  Xanthine, hypoxanthine and guanine copper(II) complexes , 1983 .

[13]  N. Katsaros,et al.  The interaction of oxomolybdenum(VI) with nucleic acid bases and nucleosides , 1982 .

[14]  M. Kastner,et al.  Structural correlation and metal ion movement in stable pentaammineruthenium(III)-hypoxanthine complexes , 1981 .

[15]  B. Graves,et al.  METAL ION INTERACTIONS WITH 8-AZAPURINES. SYNTHESIS AND STRUCTURE OF DICHLOROBIS(8-AZAADENINE)MERCURY(II) AND TETRAAQUABIS(8-AZAHYPOXANTHINATO)MERCURY(II) , 1981 .

[16]  N. Karayannis,et al.  Characterization studies of adenine complexes with 3d metal perchlorates , 1981 .

[17]  N. Karayannis,et al.  Purine complexes with divalent 3d metal perchlorates , 1980 .

[18]  N. Karayannis,et al.  Purine complexes with divalent 3d metal chlorides , 1980 .

[19]  C. Beetz,et al.  The low frequency vibrations of pyrimidine and purine bases , 1980 .

[20]  S. Shirotake,et al.  Complexes between Nucleic Acid Bases and Bivalent Metal Ions. II. : Complexes formed by Guanine or Cytosine, and Zinc (II) , 1978 .

[21]  M. Clarke.  Linkage isomers of pentaammineruthenium-hypoxanthine complexes , 1977 .

[22]  M. Inoue,et al.  Magnetic interaction in metal complexes with bridging nitrogen-heterocyclic ligands , 1976 .

[23]  W. Beck,et al.  Neue Übergangsmetallkomplexe mit Nuclein-Basen und Nucleosiden , 1976 .

[24]  E. D. Estes,et al.  Interaction of metal ions with 8-azapurines. II. Synthesis and structure of bis(8-azahypoxanthinato)tetraaquocadmium(II). , 1976, Journal of the American Chemical Society.

[25]  A. Scozzafava,et al.  Single-crystal polarized electronic spectra of the pentakis(2-picoline N-oxide)cobalt(II) perchlorate complex , 1975 .

[26]  J. Driscoll,et al.  Nmr spectral characteristics of N‐H protons in purine derivatives , 1973 .

[27]  G. W. Inman,et al.  Magnetism of methyl-substituted pyrazine complexes of copper(II) , 1972 .

[28]  E. Sletten.  Crystallographic studies of metal–nucleotide base complexes. II. Bis-(6-hydroxypurine)copper(II) chloride trihydrate , 1970 .

[29]  L. Sacconi.  Some factors governing the spin-multiplicity of five-co-ordinate complexes of cobalt(II) and nickel(II) , 1970 .

[30]  M. Labes,et al.  Spin-free and spin-paired transition metal perchlorate complexes of 2,6-lutidine N-oxide , 1969 .

[31]  R. Weiss,et al.  Das komplexchemische Verhalten von Pyrimidinabkömmlingen, XI. Die Stabilitätskonstanten einiger Purin- und Pyrimidin- kupfer(II)-Komplexe , 1969 .

[32]  V. Hrehorovich,et al.  Xanthinuria, psoriasis and arthritis. , 1969, The American journal of medicine.

[33]  A. Lever,et al.  Stereochemistry of amine oxide metal complexes , 1968 .

[34]  R. A. Krause,et al.  Complexes of Nickel(II) with Acetonitrile. Coordination of Perchlorate , 1965 .

[35]  J. Ferraro,et al.  Far‐Infrared Spectra of Anhydrous Metallic Nitrates , 1965 .

[36]  I. Tinoco,et al.  Correlations in the Ultraviolet Spectra of the Purine and Pyrimidine Bases1 , 1965 .

[37]  H. Venner,et al.  [THE COMPLEX CHEMICAL BEHAVIOR OF PYRIMIDINE DERIVATIVES. IV. THE COMPLEX CHEMICAL BEHAVIOR OF HYDROXYPURINES TOWARDS COPPER (II)]. , 1965, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

[38]  T. Shimanouchi,et al.  Infrared absorption spectra of aquo complexes and the nature of co-ordination bonds , 1964 .

[39]  R. Nyholm,et al.  238. Metal–pyrazine complexes. Part I. Compounds with cobalt(II) halides , 1962 .

[40]  A. Underhill,et al.  592. The infrared spectra of some transition-metal perchlorates , 1961 .

[41]  D. J. Brown,et al.  136. Purine studies. Part III. The structure of the monohydroxy- and monomercapto-purines : some thiazole[5 : 4-d]pyrimidines , 1957 .

[42]  E. Blout,et al.  Absorption Spectra. VIII. The Infrared Spectra of Some Purines and Pyrimidines1,2 , 1950 .