Improving yeast strains using recyclable integration cassettes, for the production of plant terpenoids

[1]  J. Weissman,et al.  A general lack of compensation for gene dosage in yeast , 2010, Molecular systems biology.

[2]  Jens Nielsen,et al.  Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae , 2010, Biotechnology and bioengineering.

[3]  H. Takagi,et al.  Metabolic Engineering of Saccharomyces cerevisiae for Astaxanthin Production and Oxidative Stress Tolerance , 2009, Applied and Environmental Microbiology.

[4]  J. Gershenzon,et al.  Monoterpene and sesquiterpene synthases and the origin of terpene skeletal diversity in plants. , 2009, Phytochemistry.

[5]  R. Hampton,et al.  Geranylgeranyl Pyrophosphate Is a Potent Regulator of HRD-dependent 3-Hydroxy-3-methylglutaryl-CoA Reductase Degradation in Yeast* , 2009, The Journal of Biological Chemistry.

[6]  Andreas Schirmer,et al.  New microbial fuels: a biotech perspective. , 2009, Current opinion in microbiology.

[7]  J. Keasling,et al.  Biosynthesis of plant isoprenoids: perspectives for microbial engineering. , 2009, Annual review of plant biology.

[8]  E. Sakuradani,et al.  Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols , 2009, Applied Microbiology and Biotechnology.

[9]  P. Vasey.  Ovarian cancer: front-line standard treatment in 2008. , 2008, Annals of oncology : official journal of the European Society for Medical Oncology.

[10]  Jay D Keasling,et al.  Redesigning enzymes based on adaptive evolution for optimal function in synthetic metabolic pathways. , 2008, Chemistry & biology.

[11]  Jay D Keasling,et al.  Redirection of flux through the FPP branch‐point in Saccharomyces cerevisiae by down‐regulating squalene synthase , 2008, Biotechnology and bioengineering.

[12]  S. Jennewein,et al.  Metabolic engineering of taxadiene biosynthesis in yeast as a first step towards Taxol (Paclitaxel) production. , 2008, Metabolic engineering.

[13]  Jens Nielsen,et al.  Production of plant sesquiterpenes in Saccharomyces cerevisiae: Effect of ERG9 repression on sesquiterpene biosynthesis , 2008, Biotechnology and bioengineering.

[14]  P. Tsichlis,et al.  Old Yellow Enzymes, Highly Homologous FMN Oxidoreductases with Modulating Roles in Oxidative Stress and Programmed Cell Death in Yeast* , 2007, Journal of Biological Chemistry.

[15]  S. Lindquist,et al.  Phenotypic Diversity and Altered Environmental Plasticity in Arabidopsis thaliana with Reduced Hsp90 Levels , 2007, PloS one.

[16]  A. Makris,et al.  Rational Conversion of Substrate and Product Specificity in a Salvia Monoterpene Synthase: Structural Insights into the Evolution of Terpene Synthase Function[W] , 2007, The Plant Cell Online.

[17]  Shunji Takahashi,et al.  Metabolic engineering of sesquiterpene metabolism in yeast , 2007, Biotechnology and bioengineering.

[18]  Jay D Keasling,et al.  Engineering of the pyruvate dehydrogenase bypass in Saccharomyces cerevisiae for high-level production of isoprenoids. , 2007, Metabolic engineering.

[19]  Jay D Keasling,et al.  Production of isoprenoid pharmaceuticals by engineered microbes , 2006, Nature chemical biology.

[20]  J. Rine,et al.  A Role for Sterol Levels in Oxygen Sensing in Saccharomyces cerevisiae , 2006, Genetics.

[21]  Timothy S. Ham,et al.  Production of the antimalarial drug precursor artemisinic acid in engineered yeast , 2006, Nature.

[22]  Robert M. Long,et al.  Genetic engineering of taxol biosynthetic genes in Saccharomyces cerevisiae. , 2006, Biotechnology and bioengineering.

[23]  Ronald W. Davis,et al.  Mechanisms of Haploinsufficiency Revealed by Genome-Wide Profiling in Yeast , 2005, Genetics.

[24]  A. Makris,et al.  Differential Roles of Tau Class Glutathione S-Transferases in Oxidative Stress* , 2004, Journal of Biological Chemistry.

[25]  J. Dangl,et al.  Cytosolic HSP90 associates with and modulates the Arabidopsis RPM1 disease resistance protein , 2003, The EMBO journal.

[26]  E. O’Shea,et al.  Global analysis of protein localization in budding yeast , 2003, Nature.

[27]  J. Hegemann,et al.  A second set of loxP marker cassettes for Cre-mediated multiple gene knockouts in budding yeast. , 2002, Nucleic acids research.

[28]  S. Jennewein,et al.  Taxol: biosynthesis, molecular genetics, and biotechnological applications , 2001, Applied Microbiology and Biotechnology.

[29]  D. Stillman,et al.  Yeast vectors for integration at the HO locus. , 2001, Nucleic acids research.

[30]  B. M. Lange,et al.  Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[31]  J. Gershenzon,et al.  Development of peltate glandular trichomes of peppermint. , 2000, Plant physiology.

[32]  Johnson,et al.  Genetic variation of volatiles and rosmarinic acid in populations of Salvia fruticosa mill growing in Crete. , 2000, Biochemical systematics and ecology.

[33]  R. Gardner,et al.  A ‘distributed degron’ allows regulated entry into the ER degradation pathway , 1999, The EMBO journal.

[34]  K. Overvad,et al.  Coenzyme Q10 in health and disease , 1999, European Journal of Clinical Nutrition.

[35]  A. Makris,et al.  Evaluation of the genetic diversity of Salvia fruticosa Mill. clones using RAPD markers and comparison with the essential oil profiles , 1999 .

[36]  M. Luo,et al.  Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo. , 1999, Molecular cell.

[37]  Frank Baganz,et al.  Suitability of replacement markers for functional analysis studies inSaccharomyces cerevisiae , 1997, Yeast.

[38]  W. Eisenreich,et al.  Terpenoid biosynthesis from 1-deoxy-D-xylulose in higher plants by intramolecular skeletal rearrangement. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[39]  R. Croteau,et al.  Terpenoid metabolism. , 1995, The Plant cell.

[40]  P. Waterman.  Introduction to ecological biochemistry, 4th Edition: J. B. Harborne, Academic Press, London, 1993. pp. 318+xiv. ISBN 0-12-324686-5. £20.00 , 1994 .

[41]  C. Poulter,et al.  Yeast farnesyl-diphosphate synthase: site-directed mutagenesis of residues in highly conserved prenyltransferase domains I and II. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[42]  J. Rine,et al.  Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast , 1994, The Journal of cell biology.

[43]  E. Zinser,et al.  Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterol metabolism , 1993, Journal of bacteriology.

[44]  G. Robinson,et al.  Molecular cloning and characterization of the yeast gene for squalene synthetase. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[45]  M. Rose,et al.  Loss of BiP/GRP78 function blocks translocation of secretory proteins in yeast , 1990, The Journal of cell biology.

[46]  C. Poulter,et al.  Farnesyl diphosphate synthetase. Molecular cloning, sequence, and expression of an essential gene from Saccharomyces cerevisiae. , 1989, The Journal of biological chemistry.

[47]  R. Kelly,et al.  Interaction of heavy chain binding protein (BiP/GRP78) with adenine nucleotides. , 1989, The EMBO journal.

[48]  M. Basson,et al.  Saccharomyces cerevisiae contains two functional genes encoding 3-hydroxy-3-methylglutaryl-coenzyme A reductase. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[49]  J. Gershenzon,et al.  Cloning and characterization of two different types of geranyl diphosphate synthases from Norway spruce (Picea abies). , 2008, Phytochemistry.

[50]  D. Mavroudis,et al.  Paclitaxel and docetaxel in the treatment of breast cancer. , 2008, Expert opinion on pharmacotherapy.

[51]  J. M.,et al.  Introduction to ecological biochemistry , 2008, Economic Botany.

[52]  M. Morange,et al.  Microbial Cell Factories , 2006 .

[53]  A. Bosabalidis,et al.  Glandular scale development and essential oil secretion in Origanum dictamnus L. , 2004, Planta.

[54]  R. Kaufman,et al.  A trip to the ER: coping with stress. , 2004, Trends in cell biology.

[55]  E. Golemis,et al.  Alternative yeast two-hybrid systems. The interaction trap and interaction mating. , 1997, Methods in molecular biology.

[56]  J. Gershenzon,et al.  Isolation of secretory cells from plant glandular trichomes and their use in biosynthetic studies of monoterpenes and other gland products. , 1992, Analytical biochemistry.