Serotonergic Facilitation of Forelimb Functional Recovery in Rats with Cervical Spinal Cord Injury

[1]  V. Edgerton,et al.  Novel Activity Detection Algorithm to Characterize Spontaneous Stepping During Multimodal Spinal Neuromodulation After Mid-Thoracic Spinal Cord Injury in Rats , 2020, Frontiers in Systems Neuroscience.

[2]  F. Fregni,et al.  Combining Fluoxetine and rTMS in Poststroke Motor Recovery: A Placebo-Controlled Double-Blind Randomized Phase 2 Clinical Trial , 2019, Neurorehabilitation and neural repair.

[3]  Daniel C. Lu,et al.  Engaging cervical spinal circuitry with non-invasive spinal stimulation and buspirone to restore hand function in chronic motor complete patients , 2018, Scientific Reports.

[4]  H. Leblond,et al.  Facilitation of Locomotor Spinal Networks Activity by Buspirone after a Complete Spinal Cord Lesion in Mice. , 2018, Journal of neurotrauma.

[5]  J. Grau,et al.  Ionic plasticity and pain: The loss of descending serotonergic fibers after spinal cord injury transforms how GABA affects pain , 2018, Experimental Neurology.

[6]  Y. Gerasimenko,et al.  And yet it moves: Recovery of volitional control after spinal cord injury , 2018, Progress in Neurobiology.

[7]  V. Reggie Edgerton,et al.  Weight Bearing Over-ground Stepping in an Exoskeleton with Non-invasive Spinal Cord Neuromodulation after Motor Complete Paraplegia , 2017, Front. Neurosci..

[8]  V. Reggie Edgerton,et al.  Electrical neuromodulation of the cervical spinal cord facilitates forelimb skilled function recovery in spinal cord injured rats , 2017, Experimental Neurology.

[9]  H. Neumann,et al.  Reversal Learning in Humans and Gerbils: Dynamic Control Network Facilitates Learning , 2016, Front. Neurosci..

[10]  Mengliang Zhang.  Normal Distribution and Plasticity of Serotonin Receptors after Spinal Cord Injury and Their Impacts on Motor Outputs , 2016 .

[11]  P. Wellman,et al.  Fluoxetine disrupts motivation and GABAergic signaling in adolescent female hamsters , 2016, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[12]  J. Alcorn,et al.  Human drug discrimination: A primer and methodological review. , 2016, Experimental and clinical psychopharmacology.

[13]  Lena H Ting,et al.  Long-term Training Modifies the Modular Structure and Organization of Walking , 2015 .

[14]  V. Reggie Edgerton,et al.  Evaluation of optimal electrode configurations for epidural spinal cord stimulation in cervical spinal cord injured rats , 2015, Journal of Neuroscience Methods.

[15]  Wutian Wu,et al.  Plasticity of motor network and function in the absence of corticospinal projection , 2015, Experimental Neurology.

[16]  T. Yune,et al.  Fluoxetine prevents oligodendrocyte cell death by inhibiting microglia activation after spinal cord injury. , 2015, Journal of neurotrauma.

[17]  V. Edgerton,et al.  Plasticity of subcortical pathways promote recovery of skilled hand function in rats after corticospinal and rubrospinal tract injuries , 2015, Experimental Neurology.

[18]  Jeffrey P. Cheng,et al.  A combined therapeutic regimen of buspirone and environmental enrichment is more efficacious than either alone in enhancing spatial learning in brain-injured pediatric rats. , 2014, Journal of neurotrauma.

[19]  Larry M. Jordan,et al.  5-HT2 and 5-HT7 receptor agonists facilitate plantar stepping in chronic spinal rats through actions on different populations of spinal neurons , 2014, Front. Neural Circuits.

[20]  Baoman Li,et al.  Fluoxetine and all other SSRIs are 5-HT2B Agonists - Importance for their Therapeutic Effects , 2014, Current neuropharmacology.

[21]  L. Abbott,et al.  Presynaptic inhibition of spinal sensory feedback ensures smooth movement , 2014, Nature.

[22]  H. Steinbusch,et al.  Fluoxetine Dose and Administration Method Differentially Affect Hippocampal Plasticity in Adult Female Rats , 2014, Neural plasticity.

[23]  Yohsuke R. Miyamoto,et al.  Temporal structure of motor variability is dynamically regulated and predicts motor learning ability , 2014, Nature Neuroscience.

[24]  Hui Zhong,et al.  Use of quadrupedal step training to re-engage spinal interneuronal networks and improve locomotor function after spinal cord injury. , 2013, Brain : a journal of neurology.

[25]  L. Maffei,et al.  Fluoxetine treatment promotes functional recovery in a rat model of cervical spinal cord injury , 2013, Scientific Reports.

[26]  R. Marcon,et al.  Effects of antidepressant and treadmill gait training on recovery from spinal cord injury in rats , 2013, Spinal Cord.

[27]  P. Whelan,et al.  Serotonin 1A Receptors Alter Expression of Movement Representations , 2013, The Journal of Neuroscience.

[28]  N. Mello,et al.  Effects of Chronic Buspirone Treatment on Nicotine and Concurrent Nicotine+Cocaine Self-Administration , 2013, Neuropsychopharmacology.

[29]  L. Uphouse,et al.  Factors influencing fluoxetine-induced sexual dysfunction in female rats , 2012, Behavioural Brain Research.

[30]  S. Micera,et al.  Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury , 2012, Science.

[31]  P. Guertin,et al.  Functional and Physiological Effects of Treadmill Training Induced by Buspirone, Carbidopa, and L-DOPA in Clenbuterol-Treated Paraplegic Mice , 2012, Neurorehabilitation and neural repair.

[32]  P. Guertin,et al.  Effects on Locomotion, Muscle, Bone, and Blood Induced by a Combination Therapy Eliciting Weight-Bearing Stepping in Nonassisted Spinal Cord–Transected Mice , 2011, Neurorehabilitation and neural repair.

[33]  Jialing Liu,et al.  Fluoxetine increases hippocampal neurogenesis and induces epigenetic factors but does not improve functional recovery after traumatic brain injury. , 2011, Journal of neurotrauma.

[34]  M. Stephens,et al.  Motoneuron excitability and muscle spasms are regulated by 5-HT2B and 5-HT2C receptor activity. , 2011, Journal of neurophysiology.

[35]  A. Tanoue,et al.  Fluoxetine promotes gliogenesis during neural differentiation in mouse embryonic stem cells , 2010, Journal of neuroscience research.

[36]  T. Hortobágyi,et al.  Teager–Kaiser energy operator signal conditioning improves EMG onset detection , 2010, European Journal of Applied Physiology.

[37]  Ian Q. Whishaw,et al.  The Ladder Rung Walking Task: A Scoring System and its Practical Application. , 2009, Journal of visualized experiments : JoVE.

[38]  M. Toth,et al.  Paradoxical anxiogenic response of juvenile mice to fluoxetine , 2009, Neuropsychopharmacology.

[39]  J. Hagan,et al.  Fluoxetine administration modulates the cytoskeletal microtubular system in the rat hippocampus , 2009, Synapse.

[40]  P. Guertin,et al.  Role of spinal 5‐HT2 receptor subtypes in quipazine‐induced hindlimb movements after a low‐thoracic spinal cord transection , 2008, The European journal of neuroscience.

[41]  Sarah A. Dunlop,et al.  Activity-dependent plasticity: implications for recovery after spinal cord injury , 2008, Trends in Neurosciences.

[42]  L. Maffei,et al.  The Antidepressant Fluoxetine Restores Plasticity in the Adult Visual Cortex , 2008, Science.

[43]  Cassie Wilson,et al.  Coordination variability and skill development in expert triple jumpers , 2008, Sports biomechanics.

[44]  Dawn L. Merrett,et al.  Reaching training in rats with spinal cord injury promotes plasticity and task specific recovery. , 2007, Brain : a journal of neurology.

[45]  C. Cotman,et al.  Wheel running and fluoxetine antidepressant treatment have differential effects in the hippocampus and the spinal cord , 2007, Neuroscience.

[46]  O. Kiehn.  Locomotor circuits in the mammalian spinal cord. , 2006, Annual review of neuroscience.

[47]  I. Whishaw,et al.  Limits on recovery in the corticospinal tract of the rat: Partial lesions impair skilled reaching and the topographic representation of the forelimb in motor cortex , 2005, Brain Research Bulletin.

[48]  C. Léránth,et al.  Short‐term treatment with the antidepressant fluoxetine triggers pyramidal dendritic spine synapse formation in rat hippocampus , 2005, The European journal of neuroscience.

[49]  M. A. Haleem,et al.  Somatodendritic and postsynaptic serotonin-1A receptors in the attenuation of haloperidol-induced catalepsy , 2004, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[50]  R. Duman,et al.  Chronic olanzapine or fluoxetine administration increases cell proliferation in hippocampus and prefrontal cortex of adult rat , 2004, Biological Psychiatry.

[51]  B. Pleger,et al.  Fluoxetine facilitates use-dependent excitability of human primary motor cortex , 2004, Clinical Neurophysiology.

[52]  F. Chollet,et al.  Fluoxetine modulates motor performance and cerebral activation of patients recovering from stroke , 2001, Annals of neurology.

[53]  E. Bizzi,et al.  New perspectives on spinal motor systems , 2000, Nature Reviews Neuroscience.

[54]  M. Millan,et al.  Buspirone modulates basal and fluoxetine-stimulated dialysate levels of dopamine, noradrenaline and serotonin in the frontal cortex of freely moving rats: activation of serotonin1A receptors and blockade of α2-adrenergic receptors underlie its actions , 1999, Neuroscience.

[55]  I. Whishaw,et al.  Complete Compensation in Skilled Reaching Success with Associated Impairments in Limb Synergies, after Dorsal Column Lesion in the Rat , 1999, The Journal of Neuroscience.

[56]  V R Edgerton,et al.  Locomotor capacity attributable to step training versus spontaneous recovery after spinalization in adult cats. , 1998, Journal of neurophysiology.

[57]  P. Tonin,et al.  Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy. , 1996, Stroke.

[58]  A. Meneses,et al.  Effect of fluoxetine on learning and memory involves multiple 5-HT systems , 1995, Pharmacology Biochemistry and Behavior.

[59]  P. Hrdina,et al.  Chronic fluoxetine treatment upregulates 5‐HT uptake sites and 5‐HT2 receptors in rat brain: An autoradiographic study , 1993, Synapse.

[60]  I. Whishaw,et al.  Rats (Rattus norvegicus) modulate eating speed and vigilance to optimize food consumption: effects of cover, circadian rhythm, food deprivation, and individual differences. , 1992, Journal of comparative psychology.

[61]  V R Edgerton,et al.  EMG patterns of rat ankle extensors and flexors during treadmill locomotion and swimming. , 1991, Journal of applied physiology.

[62]  L. Jordan,et al.  Serotonin controls initiation of locomotion and afferent modulation of coordination via 5‐HT7 receptors in adult rats , 2017, The Journal of physiology.

[63]  Y. Rossetti,et al.  Improvement of grasping after motor imagery in C6-C7 tetraplegia: A kinematic and MEG pilot study. , 2015, Restorative neurology and neuroscience.

[64]  Ranu Jung,et al.  Activity-dependent plasticity in spinal cord injury. , 2008, Journal of rehabilitation research and development.

[65]  V. Reggie Edgerton,et al.  Neural Darwinism in the Mammalian Spinal Cord , 2001 .

[66]  M. Boyeson.  Effects of fluoxetine and maprotiline on functional recovery in poststroke hemiplegic patients undergoing rehabilitation therapy. , 1996, Stroke.

[67]  Anne W. Schmidt,et al.  The clinical utility of pharmacological agents that act at serotonin receptors. , 1989, The Journal of neuropsychiatry and clinical neurosciences.

[68]  N. A. Bernshteĭn.  The co-ordination and regulation of movements , 1967 .