Long-term Outcome of Kidney Transplantation in 6 Patients With Autoimmune Polyendocrinopathy-candidiasis-ectodermal Dystrophy

polyendocrinopathy-candidiasis-ecto-dermal dystrophy (APECED; autoimmune poly-endocrine syndrome type 1; OMIM 240300) is caused by mutations in the autoimmune regulator gene ( AIRE ) that lead to failure of negative selection of autoreactive T cells and to impaired function of regulatory T cells. 1 Hypoparathyroidism and primary adrenal insufficiency are the most common early endocrinopathies, but new autoimmune manifestations may appear throughout life. are 3 There case reports (KT) in