Therapeutic vaccines and immune-based therapies for the treatment of chronic hepatitis B: perspectives and challenges.
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Qiang Deng | M. Mancini-Bourgine | M. Michel | Marie-Louise Michel | Maryline Mancini-Bourgine | Q. Deng
[1] Ding‐Shinn Chen. Hepatitis B vaccination: The key towards elimination and eradication of hepatitis B. , 2009, Journal of hepatology.
[2] Y. Wen,et al. [Advances on antigen-antibody immunogenic complex therapeutic vaccine for viral hepatitis B]. , 2009, Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology.
[3] B. Rehermann. Chronic infections with hepatotropic viruses: mechanisms of impairment of cellular immune responses. , 2007, Seminars in liver disease.
[4] J. Donnelly,et al. DNA Vaccines: Progress and Challenges1 , 2005, The Journal of Immunology.
[5] A. Nagler,et al. Ablation of persistent hepatitis B by bone marrow transplantation from a hepatitis B-immune donor. , 1993, Gastroenterology.
[6] F. Chisari,et al. Oscillating CD8(+) T cell effector functions after antigen recognition in the liver. , 2005, Immunity.
[7] H. Ueno,et al. Harnessing human dendritic cell subsets for medicine , 2010, Immunological reviews.
[8] Alessandro Sette,et al. Rational Design of a Multiepitope Vaccine Encoding T-Lymphocyte Epitopes for Treatment of Chronic Hepatitis B Virus Infections , 2007, Journal of Virology.
[9] Melinda Fitzgerald,et al. Immunol. Cell Biol. , 1995 .
[10] S. Urban,et al. T cells redirected against hepatitis B virus surface proteins eliminate infected hepatocytes. , 2008, Gastroenterology.
[11] T. Mak,et al. Adjuvant IL-7 antagonizes multiple cellular and molecular inhibitory networks to enhance immunotherapies , 2009, Nature Medicine.
[12] E. Wherry,et al. Molecular signature of CD8+ T cell exhaustion during chronic viral infection. , 2007, Immunity.
[13] H. Davis,et al. DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[14] Zheng Zhang,et al. Transfusion of autologous cytokine-induced killer cells inhibits viral replication in patients with chronic hepatitis B virus infection. , 2009, Clinical immunology.
[15] A. Bertoletti,et al. Lamivudine treatment can restore T cell responsiveness in chronic hepatitis B. , 1998, The Journal of clinical investigation.
[16] J. Kwekkeboom,et al. Functional impairment of myeloid and plasmacytoid dendritic cells of patients with chronic hepatitis B , 2004, Hepatology.
[17] C. Gibbs,et al. Antiviral effect of adefovir in combination with a DNA vaccine in the duck hepatitis B virus infection model. , 2003, Journal of hepatology.
[18] A. Prince,et al. Successful nucleic acid based immunization of newborn chimpanzees against hepatitis B virus. , 1997, Vaccine.
[19] A. Bertoletti,et al. Transient restoration of anti-viral T cell responses induced by lamivudine therapy in chronic hepatitis B. , 2003, Journal of hepatology.
[20] Adeeba Kamarulzaman,et al. AIDS Res Hum Retroviruses , 2006 .
[21] Z. Zou,et al. Circulating and Liver Resident CD4+CD25+ Regulatory T Cells Actively Influence the Antiviral Immune Response and Disease Progression in Patients with Hepatitis B1 , 2006, The Journal of Immunology.
[22] E. Rando,et al. Phase I clinical trial in healthy adults of a nasal vaccine candidate containing recombinant hepatitis B surface and core antigens. , 2007, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
[23] A. Boonstra,et al. Dendritic cells in chronic viral hepatitis B and C: victims or guardian angels? , 2009, Gut.
[24] A. Bertoletti,et al. PD‐1/PD‐L1 pathway and T‐cell exhaustion in chronic hepatitis virus infection , 2010, Journal of viral hepatitis.
[25] P. Galle,et al. Clinical and immunological efficacy of intradermal vaccine plus lamivudine with or without interleukin‐2 in patients with chronic hepatitis B , 2002, Journal of medical virology.
[26] M. Maini,et al. The molecular basis of the failed immune response in chronic HBV: therapeutic implications. , 2010, Journal of hepatology.
[27] Y. Hiasa,et al. In vivo immunization by vaccine therapy following virus suppression by lamivudine: a novel approach for treating patients with chronic hepatitis B. , 2005, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.
[28] C. Rouzioux,et al. Interruption of antiretroviral therapy initiated during primary HIV-1 infection: impact of a therapeutic vaccination strategy combined with interleukin (IL)-2 compared with IL-2 alone in the ANRS 095 Randomized Study. , 2007, AIDS research and human retroviruses.
[29] S. Rahman,et al. Combination therapy with antiviral drugs and hepatitis B vaccine in incidentally-detected and asymptomatic chronic hepatitis virus B carriers at Bangladesh. , 2010, Viral immunology.
[30] M. Roggendorf,et al. The woodchuck: a model for therapeutic vaccination against hepadnaviral infection. , 2010, Pathologie-biologie.
[31] H. Senturk,et al. Efficacy of Pre-S-containing HBV Vaccine Combined with Lamivudine in the Treatment of Chronic HBV Infection , 2009, Digestive Diseases and Sciences.
[32] Roger Williams,et al. Modulation of the CD8 -T-Cell Response by CD4 CD25 Regulatory T Cells in Patients with Hepatitis B Virus Infection , 2005 .
[33] A. Untergasser,et al. Dendritic cells take up viral antigens but do not support the early steps of hepatitis B virus infection , 2006, Hepatology.
[34] J. Dienstag,et al. Hepatitis B Virus Infection , 2010 .
[35] K. Lamberth,et al. Breaking tolerance in hepatitis B surface antigen (HBsAg) transgenic mice by vaccination with cross‐reactive, natural HBsAg variants , 2003, European journal of immunology.
[36] Y. Sung,et al. Correlation of antiviral T-cell responses with suppression of viral rebound in chronic hepatitis B carriers: a proof-of-concept study , 2006, Gene Therapy.
[37] L. Nie,et al. Autologus dendritic cell vaccine for chronic hepatitis B carriers: a pilot, open label, clinical trial in human volunteers. , 2010, Vaccine.
[38] E. Kuipers,et al. Regulatory T cells contribute to the impaired immune response in patients with chronic hepatitis B virus infection , 2005, Hepatology.
[39] Lieping Chen,et al. B7-H1 Up-Regulation on Myeloid Dendritic Cells Significantly Suppresses T Cell Immune Function in Patients with Chronic Hepatitis B1 , 2007, The Journal of Immunology.
[40] C. Brander,et al. Host Ethnicity and Virus Genotype Shape the Hepatitis B Virus-Specific T-Cell Repertoire , 2008, Journal of Virology.
[41] Zheng-hong Yuan,et al. A Randomized Controlled Phase IIb Trial of Antigen-Antibody Immunogenic Complex Therapeutic Vaccine in Chronic Hepatitis B Patients , 2008 .
[42] A. Folgori,et al. Prime-boost vectored malaria vaccines: Progress and prospects , 2010, Human vaccines.
[43] F. Zoulim,et al. Hepatitis B virus resistance to nucleos(t)ide analogues. , 2009, Gastroenterology.
[44] M. Massari,et al. Early kinetics of innate and adaptive immune responses during hepatitis B virus infection , 2009, Gut.
[45] Geoffrey Dusheiko,et al. Longitudinal Analysis of CD8+ T Cells Specific for Structural and Nonstructural Hepatitis B Virus Proteins in Patients with Chronic Hepatitis B: Implications for Immunotherapy , 2004, Journal of Virology.
[46] M. Massari,et al. Antiviral intrahepatic T-cell responses can be restored by blocking programmed death-1 pathway in chronic hepatitis B. , 2010, Gastroenterology.
[47] A. Bertoletti,et al. Therapeutic vaccination and novel strategies to treat chronic HBV infection , 2009, Expert review of gastroenterology & hepatology.
[48] Mengji Lu,et al. Immunization of Woodchucks with Plasmids Expressing Woodchuck Hepatitis Virus (WHV) Core Antigen and Surface Antigen Suppresses WHV Infection , 1999, Journal of Virology.
[49] F. Lemonnier,et al. Multiepitopic HLA-A*0201-Restricted Immune Response Against Hepatitis B Surface Antigen After DNA-Based Immunization , 2000, The Journal of Immunology.
[50] C. Bréchot,et al. Efficacy and limitations of a specific immunotherapy in chronic hepatitis B. , 2001, Journal of hepatology.
[51] N. Horiike,et al. Safety and efficacy of hepatitis B surface antigen-pulsed dendritic cells in human volunteers. , 2004, Hepatology research : the official journal of the Japan Society of Hepatology.
[52] B. Tennant,et al. Immunization with Surface Antigen Vaccine Alone and after Treatment with 1-(2-Fluoro-5-Methyl-β-l-Arabinofuranosyl)-Uracil (l-FMAU) Breaks Humoral and Cell-Mediated Immune Tolerance in Chronic Woodchuck Hepatitis Virus Infection , 2002, Journal of Virology.
[53] P. Klenerman,et al. Temporal analysis of early immune responses in patients with acute hepatitis B virus infection. , 2009, Gastroenterology.
[54] D. Ganem,et al. Hepatitis B virus infection--natural history and clinical consequences. , 2004, The New England journal of medicine.
[55] A. Sette,et al. Immunogenicity and Tolerogenicity of Hepatitis B Virus Structural and Nonstructural Proteins: Implications for Immunotherapy of Persistent Viral Infections , 2002, Journal of Virology.
[56] Wei Lu,et al. Therapeutic dendritic-cell vaccine for chronic HIV-1 infection , 2004, Nature Medicine.
[57] G. Freeman,et al. Restoring function in exhausted CD8 T cells during chronic viral infection , 2006, Nature.
[58] E. Wherry,et al. Antigen-independent memory CD8 T cells do not develop during chronic viral infection. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[59] D. Scott‐Algara,et al. Induction or expansion of T‐cell responses by a hepatitis B DNA vaccine administered to chronic HBV carriers , 2004, Hepatology.
[60] G. Lau,et al. Therapeutic vaccination of chronic hepatitis B patients with virus suppression by antiviral therapy: a randomized, controlled study of co-administration of HBsAg/AS02 candidate vaccine and lamivudine. , 2007, Vaccine.
[61] A. Bertoletti,et al. Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection? , 2000, Current opinion in microbiology.
[62] A. Bertoletti,et al. Engineering virus-specific T cells that target HBV infected hepatocytes and hepatocellular carcinoma cell lines. , 2011, Journal of hepatology.
[63] Scott N. Mueller,et al. Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection , 2008, The Journal of experimental medicine.
[64] K. Eguchi,et al. Randomized Controlled Study Investigating Viral Suppression and Serological Response following PreS 1 / PreS 2 / S Vaccine Therapy Combined with Lamivudine Treatment in HBeAg-Positive Patients with Chronic Hepatitis B , 2009 .
[65] E. Kuipers,et al. Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients. , 2008, Clinical immunology.
[66] B. Rehermann,et al. Immunology of hepatitis B virus and hepatitis C virus infection , 2005, Nature Reviews Immunology.
[67] M. Mancini-Bourgine,et al. Hepatitis B virus as a gene delivery vector activating foreign antigenic T cell response that abrogates viral expression in mouse models , 2009, Hepatology.
[68] W. Au,et al. A long-term follow-up study on hepatitis B surface antigen-positive patients undergoing allogeneic hematopoietic stem cell transplantation. , 2005, Blood.
[69] S. Pol,et al. Therapeutic vaccination in chronic hepatitis B virus carriers , 2006, Expert review of vaccines.
[70] N. Leung. Treatment of chronic hepatitis B: Case selection and duration of therapy , 2002, Journal of gastroenterology and hepatology.
[71] P. Kellam,et al. Bim-mediated deletion of antigen-specific CD8 T cells in patients unable to control HBV infection. , 2008, The Journal of clinical investigation.
[72] J. Trojan,et al. Immunological monitoring during therapeutic vaccination as a prerequisite for the design of new effective therapies: induction of a vaccine-specific CD4+ T-cell proliferative response in chronic hepatitis B carriers. , 2002, Vaccine.
[73] Y. Hiasa,et al. Safety and immunogenicity of hepatitis B surface antigen‐pulsed dendritic cells in patients with chronic hepatitis B , 2011, Journal of viral hepatitis.
[74] N. Petrovsky,et al. Development of a nasal vaccine for chronic hepatitis B infection that uses the ability of hepatitis B core antigen to stimulate a strong Th1 response against hepatitis B surface antigen , 2004, Immunology and cell biology.
[75] F. Chisari,et al. Hydrodynamic injection of viral DNA: A mouse model of acute hepatitis B virus infection , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[76] Roger Williams,et al. Lamivudine plus interleukin‐12 combination therapy in chronic hepatitis B: Antiviral and immunological activity , 2005, Hepatology.
[77] N. Horiike,et al. Placebo-controlled trial of vaccination with hepatitis B virus surface antigen in hepatitis B virus transgenic mice. , 1997, Journal of hepatology.
[78] P. Payette,et al. CpG Oligodeoxynucleotides with Hepatitis B Surface Antigen (HBsAg) for Vaccination in HBsAg-Transgenic Mice , 2001, Journal of Virology.
[79] C. Pourcel,et al. Induction of anti‐hepatitis B surface antigen (HBsAg) antibodies in HBsAg producing transgenic mice: A possible way of circumventing “nonresponse” to HBsAg , 1993, Journal of medical virology.
[80] J. Abastado,et al. HBsAg/HLA-A2 transgenic mice: a model for T cell tolerance to hepatitis B surface antigen in chronic hepatitis B virus infection. , 2003, International immunology.
[81] K. Eguchi,et al. Randomized Controlled Study Investigating Viral Suppression and Serological Response following Pre-S1/Pre-S2/S Vaccine Therapy Combined with Lamivudine Treatment in HBeAg-Positive Patients with Chronic Hepatitis B , 2009, Antimicrobial Agents and Chemotherapy.
[82] Se-Hwan Yang,et al. Increase of Plasma IL-12/p40 Ratio Induced by the Combined Therapy of DNA Vaccine and Lamivudine Correlates with Sustained Viremia Control in CHB Carriers , 2009, Immune network.
[83] D. Webster,et al. Synergistic DNA-MVA prime-boost vaccination regimes for malaria and tuberculosis. , 2006, Vaccine.
[84] M. Mondelli,et al. Natural killer cells in viral hepatitis: facts and controversies , 2010, European journal of clinical investigation.
[85] A. Bertoletti,et al. Protection or damage: a dual role for the virus-specific cytotoxic T lymphocyte response in hepatitis B and C infection? , 2000, Current opinion in immunology.
[86] W. M. Lee,et al. Hepatitis B virus infection. , 1997, The New England journal of medicine.
[87] Chung-Che Chang,et al. Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals , 2006, Nature Medicine.
[88] D. Scott‐Algara,et al. Changes to the Natural Killer Cell Repertoire after Therapeutic Hepatitis B DNA Vaccination , 2010, PloS one.
[89] C. Sunyach,et al. Protective and therapeutic effect of DNA-based immunization against hepadnavirus large envelope protein. , 1999, Gastroenterology.
[90] B. Engels,et al. Redirecting T lymphocyte specificity by T cell receptor gene transfer--a new era for immunotherapy. , 2007, Molecular aspects of medicine.