Cerebral amyloid angiopathy‐related leukoencephalopathy: Successful steroid treatment for neurological deficits and subcortical white matter lesions partly involving the cortical gray matter

A 76‐year‐old woman developed subacute cognitive decline, consciousness impairment and right hemiparesis. Magnetic resonance imaging showed asymmetric white matter or cortical gray matter lesions, and multiple cerebral microbleeds. Pathological studies of biopsied brain specimen disclosed amyloid β‐protein deposits in the vessel walls. Repeated steroid‐pulse therapy improved clinical symptoms and resolved the cortico‐subcortical lesions. Steroid therapy should be considered for patients with amyloid β‐protein deposition in cerebral amyloid angiopathy‐related leukoencephalopathy.