Identifying selective inhibitors against the human cytosolic sialidase NEU2 by substrate specificity studies.
暂无分享,去创建一个
Xi Chen | Hai Yu | Yanhong Li | Kam Y. Lau | Hai Yu | Jingyao Qu | Xi Chen | Hongzhi Cao | Vireak Thon | Jingyao Qu | Yanhong Li | Kam Lau | Yi Chen | Hongzhi Cao | Go Sugiarto | V. Thon | Go Sugiarto | Yi Chen
[1] A. Pshezhetsky,et al. Lysosomal multienzyme complex: biochemistry, genetics, and molecular pathophysiology. , 2001, Progress in nucleic acid research and molecular biology.
[2] Mark von Itzstein,et al. Anti-influenza drugs: the development of sialidase inhibitors. , 2009, Handbook of experimental pharmacology.
[3] Tohru Suzuki,et al. Homology modeling of human sialidase enzymes NEU1, NEU3 and NEU4 based on the crystal structure of NEU2: hints for the design of selective NEU3 inhibitors. , 2006, Journal of molecular graphics & modelling.
[4] K. Yamaguchi,et al. Evidence for mitochondrial localization of a novel human sialidase (NEU4). , 2005, The Biochemical journal.
[5] Soichi Wakatsuki,et al. Crystal Structure of the Human Cytosolic Sialidase Neu2 , 2005, Journal of Biological Chemistry.
[6] P. Andrew,et al. Structure of the catalytic domain of Streptococcus pneumoniae sialidase NanA , 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.
[7] A Ballabio,et al. Cloning and characterization of NEU2, a human gene homologous to rodent soluble sialidases. , 1999, Genomics.
[8] A. Pshezhetsky,et al. Neu4, a Novel Human Lysosomal Lumen Sialidase, Confers Normal Phenotype to Sialidosis and Galactosialidosis Cells* , 2004, Journal of Biological Chemistry.
[9] G. Borsani,et al. Identification and expression of NEU3, a novel human sialidase associated to the plasma membrane. , 2000, The Biochemical journal.
[10] F. Colombo,et al. Overexpression of cytosolic sialidase Neu2 induces myoblast differentiation in C2C12 cells , 2003, FEBS letters.
[11] K. Kang,et al. Prenylated pterocarpans as bacterial neuraminidase inhibitors. , 2010, Bioorganic & medicinal chemistry.
[12] Harshal A. Chokhawala,et al. Multifunctionality of Campylobacter jejuni sialyltransferase CstII: characterization of GD3/GT3 oligosaccharide synthase, GD3 oligosaccharide sialidase, and trans-sialidase activities. , 2008, Glycobiology.
[13] S. Crennell,et al. Crystal structure of a bacterial sialidase (from Salmonella typhimurium LT2) shows the same fold as an influenza virus neuraminidase. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[14] A Ballabio,et al. Molecular cloning and characterization of NEU4, the fourth member of the human sialidase gene family. , 2004, Genomics.
[15] E. Neufeld,et al. A rapid and sensitive assay for neuraminidase: Application to cultured flbroblasts , 1979 .
[16] K. Yamaguchi,et al. Down‐regulation of sialidase NEU4 may contribute to invasive properties of human colon cancers , 2007, Cancer science.
[17] Harshal A. Chokhawala,et al. High‐Throughput Substrate Specificity Studies of Sialidases by Using Chemoenzymatically Synthesized Sialoside Libraries , 2007, Chembiochem : a European journal of chemical biology.
[18] G. Borsani,et al. Expression of a novel human sialidase encoded by the NEU2 gene. , 1999, Glycobiology.
[19] R. Schauer. Chemistry, metabolism, and biological functions of sialic acids. , 1982, Advances in carbohydrate chemistry and biochemistry.
[20] R. Dwek,et al. Structural Characterization of the 1918 Influenza Virus H1N1 Neuraminidase , 2008, Journal of Virology.
[21] E Garman,et al. Crystal structure of Vibrio cholerae neuraminidase reveals dual lectin-like domains in addition to the catalytic domain. , 1994, Structure.
[22] Keiko Hata,et al. Limited Inhibitory Effects of Oseltamivir and Zanamivir on Human Sialidases , 2008, Antimicrobial Agents and Chemotherapy.
[23] M. Itzstein. Disease-associated carbohydrate-recognising proteins and structure-based inhibitor design. , 2008 .
[24] Guogang Xu,et al. Crystal structure of the NanB sialidase from Streptococcus pneumoniae. , 2008, Journal of molecular biology.
[25] G. Borsani,et al. Recent Development in Mammalian Sialidase Molecular Biology , 2002, Neurochemical Research.
[26] T. Wada,et al. Cloning, expression, and chromosomal mapping of a human ganglioside sialidase. , 1999, Biochemical and biophysical research communications.
[27] J. Paulson,et al. Resialylated erythrocytes for assessment of the specificity of sialyloligosaccharide binding proteins. , 1987, Methods in enzymology.
[28] S. Tsuiki,et al. Purification and characterization of cytosolic sialidase from rat liver. , 1985, The Journal of biological chemistry.
[29] M. Cantz,et al. Lysosomal and plasma membrane ganglioside GM3 sialidases of cultured human fibroblasts. Differentiation by detergents and inhibitors. , 1991, Biological chemistry Hoppe-Seyler.
[30] M. Itzstein,et al. An investigation of the activity of recombinant rat skeletal muscle cytosolic sialidase , 2005, FEBS letters.
[31] T. Aoyagi,et al. Differential effect of various inhibitors on four types of rat sialidase , 1993, Glycoconjugate Journal.
[32] Harshal A. Chokhawala,et al. Sialidase substrate specificity studies using chemoenzymatically synthesized sialosides containing C5-modified sialic acids. , 2009, Organic & biomolecular chemistry.
[33] Mark von Itzstein,et al. Sialic Acid Recognition by Vibrio cholerae Neuraminidase* , 2004, Journal of Biological Chemistry.
[34] G. Magnusson,et al. Highly Stereoselective .alpha.-Sialylation. Synthesis of GM3-Saccharide and a Bis-Sialic Acid Unit , 1995 .
[35] J. Saludes,et al. Synthesis and structural characterization of sialic acid-glutamic acid hybrid foldamers as conformational surrogates of alpha-2,8-linked polysialic acid. , 2009, Journal of the American Chemical Society.
[36] Nobuhiro Suzuki,et al. Complexity in influenza virus targeted drug design: interaction with human sialidases. , 2010, Journal of medicinal chemistry.
[37] Tohru Suzuki,et al. Human sialidase inhibitors: design, synthesis, and biological evaluation of 4-acetamido-5-acylamido-2-fluoro benzoic acids. , 2009, Bioorganic & medicinal chemistry.
[38] M. Fornerod,et al. Characterization of human lysosomal neuraminidase defines the molecular basis of the metabolic storage disorder sialidosis. , 1996, Genes & development.
[39] R. Drzeniek. Substrate specificity of neuraminidases , 1973, The Histochemical Journal.
[40] P. Mitrasinovic,et al. Advances in the structure-based design of the influenza A neuraminidase inhibitors. , 2010, Current drug targets.
[41] Yanhong Li,et al. Trans-sialidase activity of Photobacterium damsela alpha2,6-sialyltransferase and its application in the synthesis of sialosides. , 2010, Glycobiology.
[42] G. Borsani,et al. Properties of Recombinant Human Cytosolic Sialidase HsNEU2 , 2004, Journal of Biological Chemistry.
[43] E. Monti,et al. Expression of Sialidase Neu2 in Leukemic K562 Cells Induces Apoptosis by Impairing Bcr-Abl/Src Kinases Signaling* , 2007, Journal of Biological Chemistry.
[44] P. Wang,et al. Sialated diazeniumdiolate: a new sialidase-activated nitric oxide donor. , 2004, Organic letters.
[45] J. Kopitz,et al. Substrate Specificity and Inhibitor Studies of a Membrane-Bound Ganglioside Sialidase Isolated from Human Brain Tissue , 2002, Biological chemistry.
[46] A. Boraston,et al. Carbohydrate recognition by a large sialidase toxin from Clostridium perfringens. , 2007, Biochemistry.
[47] Komandoor E. Achyuthan,et al. Comparative enzymology, biochemistry and pathophysiology of human exo-α-sialidases (neuraminidases) , 2001 .
[48] Tohru Suzuki,et al. Design, synthesis, and biological evaluation of human sialidase inhibitors. Part 1: selective inhibitors of lysosomal sialidase (NEU1). , 2008, Bioorganic & medicinal chemistry letters.
[49] Brandi L. Cantarel,et al. The Carbohydrate-Active EnZymes database (CAZy): an expert resource for Glycogenomics , 2008, Nucleic Acids Res..
[50] Weiliang Zhu,et al. Neuraminidase pharmacophore model derived from diverse classes of inhibitors. , 2006, Bioorganic & medicinal chemistry letters.
[51] Keiko Hata,et al. Sialidase and malignancy: A minireview , 2003, Glycoconjugate Journal.
[52] H. Hashimoto,et al. Synthesis of 2-[(2-pyridyl)amino]ethyl beta-D-lactosaminide and evaluation of its acceptor ability for sialyltransferase: a comparison with 4-methylumbelliferyl and dansyl beta-D-lactosaminide. , 2004, Carbohydrate research.
[53] J. Paulson,et al. Synthesis of linkage-specific sialoside substrates for colorimetric assay of neuraminidases. , 1991, Carbohydrate research.
[54] Achim Dickmanns,et al. Crystal structure of the polysialic acid–degrading endosialidase of bacteriophage K1F , 2005, Nature Structural &Molecular Biology.
[55] Daniel Leclerc,et al. Cloning, expression and chromosomal mapping of human lysosomal sialidase and characterization of mutations in sialidosis , 1997, Nature Genetics.
[56] J. Egebjerg,et al. Cloning, expression and characterization of a sialidase gene from Arthrobacter ureafaciens , 2005, Biotechnology and applied biochemistry.
[57] A. Pshezhetsky,et al. Molecular pathology of NEU1 gene in sialidosis , 2003, Human mutation.
[58] M. Obinata,et al. Overexpression of Plasma Membrane-associated Sialidase Attenuates Insulin Signaling in Transgenic Mice* , 2003, Journal of Biological Chemistry.
[59] K. Yamaguchi,et al. Up-regulation of plasma membrane-associated ganglioside sialidase (Neu3) in human colon cancer and its involvement in apoptosis suppression , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[60] J. Paulson,et al. The specificity of viral and bacterial sialidases for α(2–3)- and α(2–6)-linked sialic acids in glycoproteins , 1983 .
[61] Y. Kozutsumi,et al. The Molecular Basis for the Absence ofN-Glycolylneuraminic Acid in Humans* , 1998, The Journal of Biological Chemistry.
[62] A. Varki. Multiple changes in sialic acid biology during human evolution , 2008, Glycoconjugate Journal.